The aim of the study is to describe clinical characteristics, treatment, and angiographic/clinical follow-up of a contemporary SCAD population in which a large proportion of patients was treated conservatively, i.e. no mechanical revascularization bu...

Clinical Studies - Oct 16, 2014 - Dec 31, 2020

Completed

Project leader: Maeder Micha
Members: Rogowski Sebastian, Schneider Irene

1. To set up an internet-based multicenter registry for patients with LVNC. 2. To include a minimum of 200 patients with LVNC in the registry. 3. To determine complications (type, incidence, recurrence) and prognosis of patients with LVNC. Obje...

Clinical Studies - Aug 18, 2014 - Mar 31, 2024

Completed

Project leader: Haager Philipp K.
Members: Schneider Irene

Ziel dieser Studie ist es, klinische Daten über die Sicherheit und Leistung von ACUITY X4®-Elektroden bei der Anwendung im klinischen Alltag zu erheben. Für die Zwecke der PMCF (Post Market Clinical Follow-up) werden die Erfolgsrate der Implantation...

Clinical Studies - Jul 28, 2014 - Nov 1, 2016

Completed

Project leader: Ammann Peter
Members: Gemperle Michaela

A multicenter, randomized, double-blind, placebocontrolled phase III study to evaluate the efficacy, safety and tolerability of Serelaxin when added to standard therapy in acute heart failure patients The purpose of this study is to evaluate the eff...

Clinical Studies - Jun 20, 2014 - Mar 22, 2017

Completed

Project leader: Maeder Micha
Members: Gall Christian, Gemperle Michaela

To increase our knowledge on structural brain damage and its changes over time in patients with AF 2. To gain additional insights on the incidence and underlying mechanisms of cognitive decline in patients with AF 3. To improve long term risk pre...

Clinical Studies - Jun 12, 2014 - Jan 1, 2032

Ongoing

Project leader: Ammann Peter
Members: Altmann David, Gemperle Michaela, Kopp Sebastian, Fink Karin, Brenner Roman, Vetsch Susanne

GLORIA-AF: Global Registry on Long-Term Oral Anti-thrombotic Treatment in Patients with Atrial Fibrillation (Phase II/III – India and Switzerland) International, multicenter, prospective observational study for patients with newly diagnosed non-valvu...

Clinical Studies - Feb 14, 2014 - Nov 30, 2019

Completed

Project leader: Rickli Hans

Double-Blind, Randomized, Multi-Center, Placebo-Controlled, Parallel Group Study to Determine the Effects of Evolocumab (AMG 145) Treatment on Atherosclerotic Disease Burden As Measured By Intravascular Ultrasound in Subjects Undergoing Coronary Cath...

Clinical Studies - Jan 9, 2014 - Jan 9, 2018

Completed

Project leader: Rickli Hans
Members: Weilenmann Daniel, Gemperle Michaela, Rigger Johannes

A Multicenter Open-label Extension (OLE) Study to Assess the Long-term Safety and Efficacy of AMG 145 Study Phase: 3 Indication: Primary hyperlipidemia and mixed dyslipidemia Primary Objective: To characterize the safety and tolerability of long-ter...

Clinical Studies - Sep 20, 2013 - Sep 20, 2017

Completed

Project leader: Rickli Hans
Members: Gemperle Michaela, Rigger Johannes

A global post-market registry of patients with de novo lesions in previously untreated vessels treated with Absorb BVS per IFU (on-label use)

Clinical Studies - Jul 10, 2013 - Oct 1, 2015

Completed

Project leader: Weilenmann Daniel
Members: Vollenbroich Rene, Gemperle Michaela

Canakinumab for the prevention of recurrences after electrical cardioversion in patients with persistent atrial fibrillation (CONVERT-AF) trial Primary objective: To determine the effect of canakinumab on atrial fibrillation (AF) recurrences withi...

Clinical Studies - Jun 20, 2013 - Jun 20, 2017

Aborted

Project leader: Ammann Peter
Members: Altmann David, Gemperle Michaela

Die Behandlung von koronaren Läsionen mit PRO-Kinetic Energy Kobalt-Chrom Metall Stent (BIOHELIX II) Das primäre Ziel dieser Studie ist der Nachweis der klinischen Leistungsfähigkeit des PRO-Kinetic Energy Stents bei Patienten mit Atherosklerose in...

Clinical Studies - May 24, 2013 - May 24, 2017

Aborted

Project leader: Rickli Hans
Members: Schneider Irene

A Double-blind, Randomized, Placebo and Ezetimibe Controlled, Multicenter Study to Evaluate Safety, Tolerability and Efficacy of AMG 145 on LDL-C in Combination With Statin Therapy in Subjects With Primary Hypercholesterolemia and Mixed Dyslipidemia;

Clinical Studies - Apr 1, 2013 - Mar 3, 2014

Completed

Project leader: Rickli Hans
Members: Schefer Mirjam, Vollenbroich Rene

The main objective of this study is to evaluate the safety and effectiveness of the COBRA PzF Coronary Stent System in the treatment of de novo lesions in native coronary arteries. The COBRA PzF Coronary Stent System is a balloon-expandable bare met...

Clinical Studies - Mar 22, 2013 - Mar 31, 2021

Completed

Project leader: Weilenmann Daniel
Members: Schneider Irene, Schefer Mirjam

Eine prospektive Studie zur Prognostizierbarkeit der Therapie Qualität mit Priorität auf die schmerzfreie ATP Therapie Das Ziel dieser klinischen Studie ist es, die Effektivität und die Auftretungshäufigkeit der vom ICD-Gerät (Implantierbarer Kardio...

Clinical Studies - Jan 3, 2013 - Dec 31, 2015

Completed

Project leader: Ammann Peter
Members: Altmann David, Rohner Franziska, Gemperle Michaela, Schefer Mirjam

Importance of Long-Term Follow-up of the ORIGIN Participants, the ORIGINALE (ORIGIN and Legacy Effects) Study

Clinical Studies - Nov 19, 2012 - Nov 19, 2016

Completed

Project leader: Brändle Michael
Members: Rickli Hans, Gemperle Michaela

Rechts- versus links apikale transvenöse Stimulation bei Patienten mit erhaltener links ventrikulärer systolischer Funktion, Bei Patienten die einen Herzschrittmacher benötigen wird die ventrikuläre Elektrode herkömmlicherweise apikal implantiert,...

Clinical Studies - Aug 16, 2012 - Aug 16, 2016

Aborted

Project leader: Ammann Peter
Members: Gemperle Michaela, Schefer Mirjam, Haager Philipp K.

Clinical Evaluation of new Terumo drug eluting coronary stent system in the treatment of patients with coronary artery disease.

Clinical Studies - Jul 2, 2012 - Jul 2, 2016

Completed

Project leader: Weilenmann Daniel
Members: Schneider Irene

Die Studie ist eine prospektive invasive, longitudinale Pilot Studie an hyperthyreoten Patienten mit Frage nach pulmonaler Hypertonie; 2.1 Häufigkeit der pulmonalen Hypertonie bei Patienten mit Hyperthyreose 2.1.1. Definition der pulmonalen Hyper...

Clinical Studies - Jun 1, 2012 - Dec 31, 2022

Completed

Project leader: Ammann Peter, Brändle Michael
Members: Locher Rebecca, Gemperle Michaela, Drescher Tilman, Vetsch Susanne, Schneider Irene, Brenner Roman

Europäische Multinationale Studie zur Prävention von Thromboembolien bei Vorhofflimmern DSE-EAF-01-11 Vorhofflimmern (VHF) ist die häufigste Herzrhythmusstörung im klinischen Alltag, von der ca.1-2% der allgemeinen Bevölkerung betroffen sind.1, 2 Die...

Clinical Studies - May 31, 2012 - Dec 31, 2013

Completed

Project leader: Ammann Peter
Members: Gemperle Michaela

Ein randomisierter Vergleich zwischen einem Sirolimus-freisetzenden Koronarstent mit bioderadierbarem Polymer und einem Everolimusbeschichteten Koronarstent mit einem nicht bioresorbierbaren Polymer bei Patienten mit einer koronaren Herzkrankheit, be...

Clinical Studies - May 29, 2012 - May 29, 2016

Completed

Project leader: Weilenmann Daniel
Members: Schefer Mirjam, Schneider Irene