Prospective, National, Multi-Center Registry of Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) in Switzerland (SwissTAVI)

Register - Nov 4, 2024 - Dec 30, 2040

Ongoing

Members: Haager Philipp, Vetsch Susanne, Maeder Micha

Clinical Studies - Oct 1, 2024 - Dec 31, 2029

Scheduled

Project leader: Ehl Niklas
Members: Vetsch Susanne

A multicentre randomised clinical trial comparing two ablation strategies for the treatment of persistent AF (PVI only or PVI+ posterior wall ablation). IC: persistent AF, (N)OAK EC: atrial interventions, o. atrium >60mm, TAVI, Ml, >NYHA III, LVEF...

Clinical Studies - Sep 17, 2024 - Sep 17, 2027

Ongoing

Project leader: Franzeck Florian M
Members: Meier Jessica, Vetsch Susanne

The objective of this project is to evaluate and compare the signal quality of electrocardiogram (ECG) signals acquired by adhesive textile ECG electrodes (Tex) using adhesive gel electrodes (Gel) as a reference system.

Clinical Studies - Jul 1, 2024 - Dec 31, 2024

Ongoing

Project leader: Annaheim Simon, Ammann Peter
Members: Meier Jessica

The present project has several objectives. Our main goal is to evaluate the hemodynamic characteristics in particular the mean pulmonary artery wedge pressure (mPAWP) of patients with versus without bendopnea and those with high (supramedian) vers...

Clinical Studies - Jul 1, 2024 - Jun 30, 2026

Ongoing

Project leader: Maeder Micha
Members: Schneider Irene

To evaluate the continued safety and performance of the Reva Fantom Sirolismus-Eluting Bioresorbable Coronary Scaffold in nativ coronary arteries that includes incorporation of a deformable expansion technologgy and an enhanced scaffold material (Tyr...

Clinical Studies - May 6, 2024 - Jun 30, 2030

Ongoing

Project leader: Rigger Johannes
Members: Fink Karin, Schneider Irene

CARITY: A targeted approach to ensuring CARe and ActivITY persistence in mid- to older-age persons during and after cardiac rehabilitation following a cardiovascular event or intervention

Clinical Studies - Dec 1, 2023 - Dec 1, 2025

Ongoing

Project leader: Buser Marc
Members: Vetsch Susanne

prospective, observational, global, multicenter study: The objective of the VISTA Study is to evaluate the safety and performance of the Navitor valve in a realworld setting. This study is intended to satisfy post-market clinical follow-up require...

Clinical Studies - Oct 23, 2023 - Oct 30, 2030

Ongoing

Project leader: Haager Philipp K.
Members: Vetsch Susanne

A prospective, randomized, multicenter, international, open, clinical study in which the SELUTION DEB strategy was compared with the DES strategy. Study objectives: 1) At 1 year, to demonstrate non-inferiority for TVF of a treatment strategy wi...

Clinical Studies - Sep 28, 2023 - Sep 28, 2028

Ongoing

Project leader: Rigger Johannes
Members: Meier Jessica, Schneider Irene

The main hypothesis underlying the suggested research program is that autoimmune CD4+ T cells cross-reacting with bacteria in the intestinal microbiome drive not only the development of acute cardiac inflammation but maintain the perpetuation of infl...

Clinical Studies - Jul 24, 2023 - Jul 24, 2024

Automatically Closed

Project leader: Ludewig Burkhard
Members: Rickli Hans, Maeder Micha, Vetsch Susanne

The aim of the Swiss-CARE registry is a comprehensive collection of clinical data and a follow-up of patients diagnosed with cardiac amyloidosis. Patients with and without therapy will be included in the registry. This will allow us to better under...

Register - Jul 1, 2023 - Jul 1, 2033

Ongoing

Project leader: Ehl Niklas
Members: Schneider Irene

The rationale of this prospective longitudinal cohort study is to determine the short and long-term effects of an ambulatory cardiac rehabilitation program on key cardiovascular benchmark performance measures and its effects on major adverse cardiova...

Register - Jul 1, 2023 - Dec 31, 2040

Ongoing

Project leader: Buser Marc
Members: Schneider Irene

A multicenter, international, randomized, active comparator-controlled, double-blind, doubledummy, parallel-group, 2-arm, Phase 3 study to compare the efficacy and safety of the oral FXIa inhibitor asundexian (BAY 2433334) with apixaban for the preve...

Clinical Studies - Jun 1, 2023 - Jun 30, 2024

Completed

Project leader: Rickli Hans
Members: Fink Karin, Vetsch Susanne

Prospective, single arm, multi-center, international study to confirm the safety and effectiveness of the AmplatzerTM PFO Occluder and AmplatzerTM TalismanTM PFO Occluder in the post approval setting.

Clinical Studies - Jun 1, 2023 - Jun 1, 2028

Ongoing

Project leader: Chronis Joannis
Members: Meier Jessica, Vetsch Susanne

A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Olpasiran on Major Cardiovascular Events in Patients with Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein (a).

Clinical Studies - May 1, 2023 - Dec 31, 2024

Aborted

Project leader: Bilz Stefan
Members: Räss Andrea, Rickli Hans, Vetsch Susanne

A Multicenter, Cross-sectional Study to Characterize the Distribution of Lipoprotein(a) Levels Among Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD). The purpose of the study is to characterize the distribution o...

Clinical Studies - May 1, 2022 - Mar 31, 2023

Completed

Project leader: Rickli Hans
Members: Vetsch Susanne, Bilz Stefan, Räss Andrea

A longitudinal observational study of patients treated with the MitraClip system in Switzerland

Register - Apr 1, 2022 - Dec 31, 2030

Ongoing

Project leader: Haager Philipp
Members: Schneider Irene

Multi-center, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of self-administered subcutaneous selatogrel for prevention of all-cause death and treatment of acute myocardial infarction in subjec...

Clinical Studies - Jan 10, 2022 - Jan 14, 2026

Ongoing

Project leader: Maeder Micha
Members: Vetsch Susanne, Fink Karin

This study is a single armed, prospective, multi-center, observational study Planned: up to 40 study sites in the EU and selected non-EU-countries

Clinical Studies - Oct 21, 2021 - Dec 31, 2026

Ongoing

Project leader: Rigger Johannes
Members: Vetsch Susanne, Fink Karin

This study is a multinational, multicentre, non-interventional, cohort study of assessment and treatment guideline recommendations in HF patient care in a real-world setting.

Clinical Studies - Sep 30, 2021 - Dec 31, 2025

Completed

Project leader: Maeder Micha
Members: Vetsch Susanne, Schneider Irene