Projects
Search from 1158 projects:
1158 Project(s)
SAKK 63/12 Prospective cohort study with collection of clinical data and serum of patients with prostate disease
Oct 15, 2014Diese Studie umfasst die Erstellung einer Serum- und Gewebebank, sowie die Erhebung zugehöriger klinischer Daten.
Clinical Studies - Oct 15, 2014 - Oct 15, 2024
Automatically Closed
Project leader: Engeler Daniel, Gillessen Sommer Silke
Members: Rothermundt Christian, Omlin Aurelius, Putora Paul Martin, Lengwiler Daniel, Patzl Sigrid, Schaepper Sibylle, Schwab Christoph, Abt Dominik, Templeton Arnoud
Verteilung der Werte des Proliferationsmarkers Ki-67 am Kantonsspital St.Gallen
Oct 15, 20141b.1. Hintergrund Der Proliferationsmarker Ki-67 wird in der Onkologie ubiquitär verwendet. Bei der Behandlung von Brustkrebs hat er ein spezielles Gewicht bekommen, da bei einem häufigen Subtyp von Brustkrebs (Luminal-B) die Indikation für eine adju...
Clinical Studies - Oct 15, 2014 - Sep 26, 2015
Completed
Project leader: Ruhstaller Thomas
Members: Öhlschlegel Christian, Jochum Wolfram, Thürlimann Beat
Timed-up-and-go (TUG) as a generic objective measure of function in neurosurgery. Relationship to subjective measures of pain and function and quality of life
Oct 5, 2014This prospective, observational study examines the relationship between pain, functional disability and health-related quality of life (HRQoL) with the result of a simple test, the “timed-up-and-go”-Test (TUG-test) in patients with lumbar spinal dege...
Clinical Studies - Oct 5, 2014 - Oct 31, 2015
Automatically Closed
Project leader: Stienen Martin N., Corniola Marco V, Smoll Nicolas R., Gautschi Oliver P
Members: Chau Ivan, Joswig Holger, Hildebrandt Gerhard
M13-375SpoA: A Multicenter, Randomized, Double-Blind, Study Comparing the Efficacy and Safety of
Sep 9, 2014Das Ziel dieser Studie ist es, die Wirksamkeit und Sicherheit der Fortsetzung vs. des Abbruchs der Therapie mit Adalimumab 40 mg, das jede zweite Woche subkutan verabreicht wird, in Bezug auf die Aufrechterhaltung der Remission bei Probanden mit nich...
Clinical Studies - Sep 9, 2014 - Apr 7, 2017
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia
Evaluation of a Candidate Vaccine Against Uropathogenic Escherichia Coli in Women With a Clinical History of Recurrent Urinary Tract Infection
Sep 7, 2014Purpose: This Phase I multi-center placebo controlled study is conducted in healthy women with a history of recurrent urinary tract infections (UTI) aged between 18 and 70 years. GlycoVaxyn is a Swiss company that has developed a multivalent bioconju...
Healthcare Research - Sep 7, 2014 - Sep 7, 2015
Completed
Project leader: Hülder Tanja, Hornung René
Airway microbiota resistome in CF - impact on clinical management
Sep 1, 2014Cystic Fibrosis is a deadly genetic disease mainly due to chronic bacterial colonization and recurrent bacterial infections of the lungs. It has often been documented that once a certain microbial species such as Pseudomonas aeruginosa establishes, t...
Fundamental Research - Sep 1, 2014 - Dec 31, 2016
Automatically Closed
Project leader: Baty Florent
Members: Brutsche Martin, Kahlert Christian, Von Mering Christian, Vyas Rounak
PsoA: A phase III, randomized, double-blind, placebo-controlled multicenter
Aug 20, 2014Study to demonstrate the efficacy at 24 weeks and to assess the long term efficacy, safety and tolerability of secukinumab in Active Psoriatic Arthritis
Clinical Studies - Aug 20, 2014 - Aug 16, 2018
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia, Bartz-Batliner Mira, Hutz Carina Liane, Schmidig Kathrin
LVNC: Multicenter Registry for Left Ventricular Non-compaction Cardiomyopathy
Aug 18, 20141. To set up an internet-based multicenter registry for patients with LVNC. 2. To include a minimum of 200 patients with LVNC in the registry. 3. To determine complications (type, incidence, recurrence) and prognosis of patients with LVNC. Obje...
Clinical Studies - Aug 18, 2014 - Mar 31, 2024
Completed
Project leader: Haager Philipp K.
Members: Schneider Irene
ABreak: Abatacept Study to omit weekly subcutaneous injections in RA patients during holiday BREAK
Aug 7, 2014Einmalige Infusion von Abatacept zur Simulation von Ferien bei Patienten mit rheumatoider Arhtritis und Vorbehandlung mit Abatacept (Wechsel von sc auf iv und zurück).
Clinical Studies - Aug 7, 2014 - Dec 7, 2014
Completed
Project leader: Müller Rüdiger
Qualitative Interviews Runder Tisch in palliativer Situation - Teil 1 des Konzeptes Palliative Betreuung
Aug 4, 2014Seit Einführung des Konzeptes Palliative Betreuung (ehemaliger Standard 25) erheben wir vor allem quantitative Daten zur Auswertung des Standards. 2011 wurden die Multiplikatorinnen und Multiplikatoren befragt. Befragungen von Betroffenen zum Runden...
Clinical Studies - Aug 4, 2014 - Dec 1, 2015
Completed
Project leader: Büche Daniel, Grossenbacher-Gschwend Barbara, Domeisen Benedetti Franzisca
Members: Mettler Mona
A structured early palliative care intervention for patients with advanced cancer – a randomized controlled trial with a nested qualitative study - SENS Trial
Aug 1, 2014Dieses Studienprojekt, der SENS-Trial, möchte untersuchen, inwiefern eine systematische Diskussion dieser Fragen, zu einem möglichst frühen Zeitpunkt im Krankheitsverlauf zu einer erkennbaren Stressreduktion sowohl bei den Patienten, aber auch bei de...
Clinical Studies - Aug 1, 2014 - Dec 31, 2016
Automatically Closed
Project leader: Eychmuller Steffen, Nestor Karen
Members: Domeisen Benedetti Franzisca, Forster Michaela
RALLY X4
Jul 28, 2014Ziel dieser Studie ist es, klinische Daten über die Sicherheit und Leistung von ACUITY X4®-Elektroden bei der Anwendung im klinischen Alltag zu erheben. Für die Zwecke der PMCF (Post Market Clinical Follow-up) werden die Erfolgsrate der Implantation...
Clinical Studies - Jul 28, 2014 - Nov 1, 2016
Completed
Project leader: Ammann Peter
Members: Gemperle Michaela
Prevention of symptomatic skeletal events with denosumab administered every 4 weeks versus every 12 weeks: A noninferiority phase III trial (SAKK 96/12, REDUSE)
Jul 7, 2014Background: Denosumab, a monoclonal antibody against RANK-Ligand has been shown to be superior to zoledronic acid in delaying time to a first on-study skeletal-related event (SRE) in patients with solid tumors, with no effects on disease progression...
Clinical Studies - Jul 7, 2014 - Dec 31, 2026
Ongoing
Project leader: Fischer Stefanie
Members: Sakic Miranda, Quinter Janine
Phase III international, randomized study of Trabectedin plus Pegylated Liposomal Doxorubicin (PLD) versus Car-boplatin plus PLD in patients with ovarian cancer progress-ing within 6-12 months of last platinum
Jul 4, 2014Es sind keine Vergleichsdaten für Trabectedin und PLD vs. pla-tin-basierte Chemotherapie vorhanden. Ausgehend von den Ergebnissen der Studien OVA-301 und CALYPSO zielt das INOVATYON-Projekt darauf ab, die Rolle einer nicht Platin-basierten, therapeut...
Clinical Studies - Jul 4, 2014 - Apr 16, 2021
Automatically Closed
Project leader: Riniker Salome
Members: Gueller Ulrich, Ruhstaller Thomas, Weder Patrik, Thürlimann Beat, Hasler-Strub Ursula
Tobramycin
Jul 1, 2014An open-label, crossover, interventional Phase IV study to compare the ease of use of tobramycin inhalation solution and nebulized colistimethate for the treatment of pulmonary Pseudomonas aeruginosa in patients with CF
Clinical Studies - Jul 1, 2014 - Mar 18, 2015
Completed
Project leader: Brutsche Martin
Members: Finger Rebekka
GA28951
Jun 28, 2014GA28951: AN OPEN-LABEL EXTENSION AND SAFETY MONITORING STUDY OF MODERATE TO SEVERE ULCERATIVE COLITIS PATIENTS PREVIOUSLY ENROLLED IN ETROLIZUMAB PHASE III STUDIES
Clinical Studies - Jun 28, 2014 - Jun 28, 2020
Completed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
RELAX - RLX030A
Jun 20, 2014A multicenter, randomized, double-blind, placebocontrolled phase III study to evaluate the efficacy, safety and tolerability of Serelaxin when added to standard therapy in acute heart failure patients The purpose of this study is to evaluate the eff...
Clinical Studies - Jun 20, 2014 - Mar 22, 2017
Completed
Project leader: Maeder Micha
Members: Gall Christian, Gemperle Michaela
Patient-centred personalised palliative cancer care: A pilot feasibility study of patient-derived clinical benefit-guided chemotherapy in advanced non-small cell lung cancer (NSCLC) patients with a performance status (PS) of 2-3 due to lung cancer (Phönix)
Jun 16, 2014Performance status has shown to be a major negative prognostic factor in lung cancer. Because of the limited time expectancy of these patients, individual clinical benefit (Koeberle) of any intervention should be the main focus. This contrasts the ma...
Clinical Studies - Jun 16, 2014 - Dec 31, 2014
Completed
Project leader: Früh Martin
Members: Strasser Florian, Magayakalbermatten N, Behnke Nadine
SWISS AF - Swiss Atrial Fibrillation Cohort Study
Jun 12, 2014To increase our knowledge on structural brain damage and its changes over time in patients with AF 2. To gain additional insights on the incidence and underlying mechanisms of cognitive decline in patients with AF 3. To improve long term risk pre...
Clinical Studies - Jun 12, 2014 - Jan 1, 2032
Ongoing
Project leader: Ammann Peter
Members: Altmann David, Gemperle Michaela, Kopp Sebastian, Fink Karin, Brenner Roman, Vetsch Susanne
RICE: An open label, randomized study to compare the efficacy of Certolizumab pegol (CZP) plus a dynamic or fixed dose treatment strategy in patients with Rheumatoid Arthritis, a phase II study
Jun 7, 2014randomisierte Studie bei fortgeschrittener rheumatoider Arthritis mit Certolizumab, Standardtherapie DMARD/Prednison plus Certolizumab vs Therapieeskalation DMARD/Prednison mit Certolizumab und Gelenksinfiltration.
Clinical Studies - Jun 7, 2014 - Aug 31, 2018
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia, Bartz-Batliner Mira, Schmidig Kathrin, Hutz Carina Liane