Projects
Search from 1158 projects:
1158 Project(s)
AbbVie M14-115
Feb 1, 2015A Multicenter, Randomisierte, Double-Blind Study to Evaluate the Efficacyand Safety of Two Adalimumab Induction Regimens in Subjects with Moderately to Severely Active Crohns Disease and Evidence of Mucosal Ulceration
Clinical Studies - Feb 1, 2015 - Feb 15, 2018
Automatically Closed
Members: Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael, Dora Barbara
Entwicklung und Validierung einer Patienteninformationsbroschüre zur Harnleiterschienung
Jan 18, 2015Entwicklung eines systematischen Validierngsprozesses für Patienteninformationsbroschüren am Beispiel einer Aufklärungsbroschüre für Harnleiterschienen
Clinical Studies - Jan 18, 2015 - Dec 18, 2016
Automatically Closed
Project leader: Abt Dominik
Members: Schmid Hans-Peter, Betschart Patrick, Sauter Rafael, Zumstein Valentin, Staubli Sergej
Prolongation PREFER in AF Registry
Jan 15, 2015The aim of this registry is to prolong the patient observation period and recruit new patients to gain further insights into the long-term use of NOACs, including switching from Vitamin K antagonists (VKAs), to NOACs in a real life setting. This will...
Clinical Studies - Jan 15, 2015 - Mar 31, 2016
Completed
Project leader: Ammann Peter
Members: Gemperle Michaela
Impact of Sarcopenia in Curative Trimodality Therapy for Esophageal Cancer
Jan 13, 2015The aim of the study is to investigate the prevalence and course of sarcopenia in patients undergoing curative trimodality therapy for locally advanced esophageal cancer and to correlate skeletal muscle mass with treatment complications during neoadj...
Clinical Studies - Jan 13, 2015 - Dec 31, 2015
Automatically Closed
Project leader: Panje Cédric, Henke Guido
Members: Blum David
Influenza Vaccination Coverage of Health Care Workers: A Cross-Sectional Study Based on Data from a Swiss Women’s Hospital
Jan 10, 2015
Healthcare Research - Jan 10, 2015 - Feb 21, 2018
Completed
Project leader: Thanner Mirjam
Members: von Perbandt Evelyn, Hornung René
Proteasominhibitor-resistentes Multiples Myelom: Biologie und Therapieoptionen
Jan 5, 2015Proteasom-Inhibitor (PI) Resistenz ist eines der Schlüsselprobleme in der Therapie des Multiplen Myeloms (MM), der häufigsten hämatologischen Neoplasie. Wir haben in Vorarbeiten ein in vitro-Modell des PI-resistenten MM entwickelt und Biologie-basier...
Fundamental Research - Jan 5, 2015 - Dec 31, 2015
Automatically Closed
Project leader: Driessen Christoph
Members: Besse Lenka
Bestimmung der spezifischen zellulären Immunität gegen das Cytomegalovirus (CMV) zur Optimierung der Prävention der CMV-Erkrankung bei Patienten mit Organtransplantat
Jan 1, 2015Hintergrund Die CMV-Infektion ist die häufigste Viruserkrankung nach Transplantation und ist nach wie vor mit einer hohen Morbidität verbunden. Die antiviralen Medikamente haben sich in der Prävention der CMV-Infektion als nützlich erwiesen, vor all...
Clinical Studies - Jan 1, 2015 - Dec 31, 2018
Completed
Project leader: Binet Françoise-Isabelle
STD4free
Jan 1, 2015Studie zur Evaluation einer optimalen Teststrategie auf die wichtigsten sexuell übertragbaren Erkrankungen (STD) bei symptomfreien Personen
Clinical Studies - Jan 1, 2015 - Dec 31, 2015
Automatically Closed
Project leader: Vernazza Pietro
Impact of intestinal stromal cells on the function of innate lymphoid cells in an animal model for inflammatory bowel disease
Jan 1, 2015Intestinal homeostasis requires codependent interactions between the intestinal epithelium, the microbiota and the immune system. Innate lymphoid cells (ILCs) play critical roles in intestinal homeostasis, the regulation of intestinal epithelial cell...
Fundamental Research - Jan 1, 2015 - Dec 31, 2015
Automatically Closed
Project leader: Scandella Elke
Survival, Trigger and Risk, Epigenetic, eNviromental and Genetic Targets for motor neuron Health (STRENGTH)
Jan 1, 2015Dieser Studie wird als internationales Projekt europaweit an verschiedenen spezialisierten ALS-Zentren durchgeführt. Hintergrund ist die Tatsache, dass die genauen Ursachen oder Risikofaktoren, die zu der Erkrankung ALS führen zu einem grossen Teil u...
Clinical Studies - Jan 1, 2015 - Dec 31, 2017
Completed
Project leader: Burkhardt Christian, Weber Markus
Members: Neuwirth Christoph
Galathea
Jan 1, 2015Eine randomisierte, doppelblinde, kontinuierlich verabreichte, placebokontrollierte, multizentrische klinische Prüfung der Phase III zur Untersuchung der Wirksamkeit und Sicherheit von 2 Dosierungen Benralizumab (MEDI-563) bei Pat. mit moderater bis...
Clinical Studies - Jan 1, 2015 - Jan 1, 2016
Automatically Closed
Project leader: Brutsche Martin
Members: Benz Gabriel
Predictive and prognostic value of integrated exon-level expression to approach drug-response and resistance to EGFR-targeted treatment in non-small cell lung cancer
Jan 1, 2015Activating mutations in lung cancer are targeted by a series of molecularly targeted therapies. Patients harboring such mutations can receive significant benefit from these therapies. However a proportion of patients without activating mutations can...
Fundamental Research - Jan 1, 2015 - Dec 31, 2016
Automatically Closed
Project leader: Baty Florent
Members: Franzini Anca, Früh Martin, Jörger Markus, Brutsche Martin
GA28950/Hickory
Jan 1, 2015PHASE III, BLINDED, PLACEBO-CONTROLLED, MULTICENTER STUDY OF THE EFFICACY AND SAFETY OF ETROLIZUMAB DURING INDUCTION AND MAINTENANCE IN PATIENTS WITH MODERATE TO SEVERE ACTIVE ULCERATIVE COLITIS WHO ARE REFRACTORY TO OR INTOLERANT OF TNF INHIBITORS
Clinical Studies - Jan 1, 2015 - Dec 31, 2017
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
SINGLE ARM OPEN LABLE PHASE II PILOT STUDY OF CARBOPLATIN
Dec 2, 2014Study design: For the pilot trial a single stage phase II design was chosen. All patients that meet the eligibility criteria will receive carboplatin AUC3 until progression (radiological or clinical). A total of 25 patients are required for this stud...
Clinical Studies - Dec 2, 2014 - Dec 31, 2017
Automatically Closed
Project leader: Omlin Aurelius
Members: Gillessen Sommer Silke, Haile Sarah, Jochum Wolfram
Fibromyalgie: A Randomized, Double-Blind, Placebo- and Active-Controlled Study of DS-5565 for Treatment of Pain Associated with Fibromyalgia
Nov 16, 2014This is a randomized, double-blind, double-dummy, placebo- and active controlled, multi-center study of DS-5565 in subjects with pain associated with FM. Eligible subjects will be randomized in the ratio of 1:1:1:1 to receive 13 weeks of treatment wi...
Clinical Studies - Nov 16, 2014 - May 31, 2017
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia
Clinical impact of multiplex realtime PCR in respiratory tract infections
Nov 15, 2014Pathogen detection in respiratory tract infections is challenging due to lack of diagnostic gold standard with sufficient sensitivity and specificity. Viral infections likely contribute to a considerable portion of respiratory tract infections partic...
Clinical Studies - Nov 15, 2014 - Dec 31, 2015
Automatically Closed
Project leader: Albrich Werner
Members: Kahlert Christian, Rassouli Frank, Mayer Lena
"Mechanisms of Evasive Resitance in Cancer (MERiC)"
Nov 1, 2014-prospektive Beobachtungsstudie von Patienten mit HCC -Leberbiopsie vom Leberrundherd, Re-Biopsie bei Tumorprogression nach jeder Behandlung (TACE etc.) bis Behandlungsende HCC
Clinical Studies - Nov 1, 2014 - Nov 1, 2020
Automatically Closed
Project leader: Semela David
Members: Alfter Christine, Pérez Shibayama Christian Ivan
A national palliative care database: A tool to better define the needs of palliative care patients in Switzerland - SwissPALL
Nov 1, 2014
Clinical Studies - Nov 1, 2014 - Jan 1, 2016
Completed
Project leader: Büche Daniel, Strasser Florian
Members: Domeisen Benedetti Franzisca, Forster Michaela
MP0250; A phase I multi-centre, open-label, repeated-dose, dose-escalation study to assess safety, tolerability and pharmacokinetics of MP0250 in patients with advanced solid tumours
Oct 23, 2014Dies ist die erste Studie zur Anwendung des neuen Medikaments MP0250 am Menschen. Das Hauptziel ist es, dessen Sicherheit und Verträglichkeit bei Krebs-Patienten zu untersuchen. Diese Studie wird auch prüfen, wie das Medikament durch den Körper verä...
Clinical Studies - Oct 23, 2014 - Sep 30, 2016
Automatically Closed
Project leader: Omlin Aurelius
Members: Hess Dagmar, Jörger Markus, Bickel Angelika
SCAD: Spontaneous coronary artery dissection: single centre study with systematic angiographic and clinical follow-up
Oct 16, 2014The aim of the study is to describe clinical characteristics, treatment, and angiographic/clinical follow-up of a contemporary SCAD population in which a large proportion of patients was treated conservatively, i.e. no mechanical revascularization bu...
Clinical Studies - Oct 16, 2014 - Dec 31, 2020
Completed
Project leader: Maeder Micha
Members: Rogowski Sebastian, Schneider Irene