Projects
Search from 1158 projects:
1158 Project(s)
A Multicenter Phase III Randomized study with second line chemotherapy plus or minus Bevacizumab in patients with Plati-num sensitive Epithelial ovarian cancer recurrence after a Bevacizumab/chemotherapy first line
May 27, 2014Das Ovarialkarzinom (OK) stellt die sechsthäufigste Krebser-krankung bei Frauen dar und ist die weltweit achthäufigste krebsbezogene Todesursache bei Frauen. Die Methode der Wahl ist die Operation mit dem Ziel, den Tumor möglichst vollständig zu entf...
Clinical Studies - May 27, 2014 - Jun 27, 2016
Automatically Closed
Project leader: Weder Patrik
Members: Hasler-Strub Ursula, Riniker Salome, Diem Stefan, Ruhstaller Thomas
Etablierung eines humanisierten Maus-Myelom-Modells
May 1, 2014Das Labor für experimentelle Onkologie befasst sich schwerpunktmässig mit dem Einsatz von Proteasominhibitoren bei der Behandlung des Multiplen Myeloms und anderer hämatologischer Neoplasien. Bisher werden als Modellsystem Monokultur-Systeme unter Ve...
Fundamental Research - May 1, 2014 - Dec 31, 2015
Automatically Closed
Project leader: Driessen Christoph
Members: Silzle Tobias
Bern Cohort study of patients with hepatocellular carcinoma
Apr 16, 2014This is a cohort study in consecutive patients with diagnosed HCC referred to a tertiary care hospital with follow-ups every 3 months until death or transplantation.
Clinical Studies - Apr 16, 2014 - Apr 16, 2023
Automatically Closed
Project leader: Semela David
Members: Weinmann Sabine, Künzler-Heule Patrizia, Borovicka Jan, Frei Remus, Sawatzki Mikael, Semadeni Gian-Marco, Sulz Michael
Is absorption of irrigation fluid a problem in Thulium laser vaporization of the prostate? A prospective investigation using the expired breath ethanol test
Apr 15, 2014Mehr und mehr Patienten, welche eine transurethrale Resektion der Prostata aufgrund einer Blasenentleerungsproblematik benötigen, sind auf eine Antikoagulation bzw. eine Thrombozytenaggregations-hemmung angewiesen. Da bei endoskopischen Resektionen d...
Clinical Studies - Apr 15, 2014 - Apr 15, 2015
Completed
Project leader: Engeler Daniel
Members: Abt Dominik, Schwab Christoph, Filipovic Miodrag
A Phase I and stratified, multicenter Phase II trial of trans-dermal CR1447 (4-OH-testosterone) in endocrine respon-sive-HER2 negative and triple negative-androgen receptor positive metastatic or locally advanced breast cancer
Apr 14, 2014Neue Therapieoption durch endokrin wirksame Substanz bei Mammakarzinom. Neue Applikationsart als Crème, potentiell gut verträglich. Weitere endokrine Therapielinie bei Progress unter Aromataseinhibitoren, mögliche Thera-pieoption bei TNBC.
Clinical Studies - Apr 14, 2014 - Jul 23, 2017
Automatically Closed
Project leader: Riniker Salome
Members: Thürlimann Beat, Ruhstaller Thomas, Weder Patrik, Diem Stefan, Gueller Ulrich
Deutschsprachige Validierung des Ureteral Stent Symptom Questionnaire (USSQ)
Apr 3, 2014Die vorliegende Studie soll eine bereits (gemäss ausführlichem Studienprotokoll) erarbeitete Übersetzung des Fragebogens USSQ validieren. Hiermit könnte künftig auch im deutschsprachigen Raum die Morbidi-tät einliegender Harnleiterschienen erfasst we...
Clinical Studies - Apr 3, 2014 - Dec 21, 2015
Completed
Project leader: Abt Dominik, Engeler Daniel
Evaluation of a Candidate Vaccine Against Uropathogenic Escherichia Coli in Women with a Clinical History of Recurrent Urinary Tract Infection
Apr 1, 2014
Clinical Studies - Apr 1, 2014 - Sep 30, 2017
Automatically Closed
Dreidimensionale Messung der Schulterbewegung vor und nach Implantation einer inversen Schulterprothese im Vergleich zu einer gesunden Kontrollgruppe
Apr 1, 2014Zielsetzung Das Ziel des Projekts ist die prä- und postoperative Erfassung der scapulo-thorakalen Kinematik bei Patienten mit inverser Schulterprothese. Forschungsstand Bisher ist sehr wenig über die dreidimensionale Bewegung der Scapula nach Implant...
Clinical Studies - Apr 1, 2014 - Dec 1, 2017
Automatically Closed
Project leader: Jost Bernhard
Members: Zdravkovic Vilijam, Erschbamer Matthias
Disease-specific profiles of decision-making processes at multidisciplinary team conferences
Mar 14, 2014Disease-specific profiles of decision-making processes at multidisciplinary team conferences Background: The core of multidisciplinary taeam conferences (MTC) is a decision-making process depending on interaction of MTC participants. Best use of le...
Fundamental Research - Mar 14, 2014 - Dec 14, 2014
Automatically Closed
Project leader: Hitz Felicitas
Members: Ruhstaller Thomas
Blood pressure variability during the 6-minute walk test in patients with Chronic Obstructive Pulmonary Disease (COPD): A case-control study
Mar 10, 2014The proposed study will compare vSBP values during physical exercise between patients with COPD and age- and gender-matched controls. We hypothesize that vSBP during the 6MWT is increased in patients with COPD compared to age- and gender matched cont...
Fundamental Research - Mar 10, 2014 - Jun 1, 2015
Completed
Project leader: van Gestel Arnoldus J R
Members: Baty Florent, Brutsche Martin, Gajic Andreja
Warum Ärzte den Chefarztposten aufgeben: Eine explorative Untersuchung zu Motiven und Rahmenbedingungen der chefärztlichen Tätigkeit
Mar 8, 2014Das Projekt will beschreiben helfen, aus welchen Gründen Ärzte den Chefarztposten aufgeben. Darüber hinaus sollen Erkenntnisse zum beruflichen Idealbild von Chefärzten sowie zur erfolgreichen Rekrutierung und Bindung von ärztlichen Führungspersonen i...
Healthcare Research - Mar 8, 2014 - Jan 31, 2017
Completed
Project leader: Hornung René
Members: Thanner Mirjam, Milojkovic Kristina
GLORIA -AF
Feb 14, 2014GLORIA-AF: Global Registry on Long-Term Oral Anti-thrombotic Treatment in Patients with Atrial Fibrillation (Phase II/III – India and Switzerland) International, multicenter, prospective observational study for patients with newly diagnosed non-valvu...
Clinical Studies - Feb 14, 2014 - Nov 30, 2019
Completed
Project leader: Rickli Hans
Prospective Swiss pilot study using Endocuff-assisted colonoscopy in a screening population
Feb 10, 2014Introduction The adenoma detection rate (ADR) is one of the quality measures in screening colonoscopy and crucial for reducing colorectal cancer morbidity and mortality. Up to 25% of adenomas are missed during colonoscopy. Endocuff is an easy to use...
Clinical Studies - Feb 10, 2014 - Dec 23, 2014
Completed
Project leader: Sawatzki Mikael
Members: Meyenberger Christa, Frei Remus
Prostatic Artery Embolization vs. conventional TUR-P in the Treatment of Benign Prostatic Hyperplasia: A prospective randomized trial
Feb 5, 2014
Clinical Studies - Feb 5, 2014 - Apr 5, 2023
Automatically Closed
Project leader: Engeler Daniel, Abt Dominik
Members: Schmid Hans-Peter, Hechelhammer Lukas, Patzl Sigrid, Lengwiler Daniel, Haile Sarah, Maier Reinhard, Schulz Thomas
Cachexia and Toxicity: cachexia-based dosing vs. standard of care (CAT-Trial)
Jan 23, 2014Cancer cachexia is a frequent condition, characterized by muscle loss not reversible by nutrition only, caused by procatabolic (inflammatory) and hypoanabolic mechanism, with an impact on quality of life, function and survival. An association of musc...
Clinical Studies - Jan 23, 2014 - Nov 30, 2014
Automatically Closed
Project leader: Strasser Florian
Members: Blum David, Jörger Markus, Fornaro Jürgen, Magayakalbermatten N, Behnke Nadine
LUNA Studie
Jan 21, 2014Lungenkrebs ist die dritthäufigste Krebsart weltweit. Der aktuelle therapeutische Ansatz und die einzige kurative Behandlung von pulmonalen neuroendokrine Tumoren (pNET) ist eine operative Entfernung, bei der so viel wie möglich vom normalem Lungenge...
Clinical Studies - Jan 21, 2014 - Jan 21, 2014
Completed
Project leader: Brändle Michael
Members: Krull Ina
AMG 145 20120153 GLAGOV
Jan 9, 2014Double-Blind, Randomized, Multi-Center, Placebo-Controlled, Parallel Group Study to Determine the Effects of Evolocumab (AMG 145) Treatment on Atherosclerotic Disease Burden As Measured By Intravascular Ultrasound in Subjects Undergoing Coronary Cath...
Clinical Studies - Jan 9, 2014 - Jan 9, 2018
Completed
Project leader: Rickli Hans
Members: Weilenmann Daniel, Gemperle Michaela, Rigger Johannes
Human airway epithelia and pneumococcus. Polarized in vitro cell culture model to study interaction between human airway epithelia and pneumococcus
Jan 1, 2014This project aims to extend the existing human airway epithelial model to enable studies on the most relevant and lethal respiratory bacterial pathogen, Streptococcus pneumoniae (SP). The primary goal of this proposal is to show the feasibility of th...
Fundamental Research - Jan 1, 2014 - Dec 31, 2014
Automatically Closed
Project leader: Albrich Werner, Kahlert Christian
Impact of HPV on outcome in surgically treated patients with OPSCC
Jan 1, 2014Impact of HPV positivity (based on detection of p16 protein and high risk HPV-DNA in tumor tissue samples) in relation to tumor stage, grade of differentiation, gender, age and other risk factors (smoking habits, alcohol consumption, T- and N-categor...
Clinical Studies - Jan 1, 2014 - Dec 31, 2014
Completed
Project leader: Broglie Däppen Martina
Members: Stöckli Sandro, Jochum Wolfram
Structural brain changes and dysphagia in Parkinson's disease
Jan 1, 2014
Clinical Studies - Jan 1, 2014 - Dec 31, 2015
Automatically Closed
Project leader: Kägi Georg
Members: Galovic Marian, Brugger Florian, Stöckli Sandro, Müller Marlise