A Phase I and stratified, multicenter Phase II trial of trans-dermal CR1447 (4-OH-testosterone) in endocrine respon-sive-HER2 negative and triple negative-androgen receptor positive metastatic or locally advanced breast cancer

Project

A Phase I and stratified, multicenter Phase II trial of trans-dermal CR1447 (4-OH-testosterone) in endocrine respon-sive-HER2 negative and triple negative-androgen receptor positive metastatic or locally advanced breast cancer

Automatically Closed · 2014 until 2017

Riniker Salome, Thürlimann Beat, Ruhstaller Thomas, Weder Patrik, Diem Stefan, Gueller Ulrich

Type

Clinical Studies

Range

Multicentric, KSSG as participating partner

Units

Medizinische Onkologie und Hämatologie, Brustzentrum St.Gallen

Status

Automatically Closed

Start Date

2014

End Date

2017

Financing

Others

Study Design

Phase I/II

Keywords

Phase I, Phase II, CR1447, 4-OH-testosterone, breast cancer

Brief description/objective

Neue Therapieoption durch endokrin wirksame Substanz bei Mammakarzinom. Neue Applikationsart als Crème, potentiell gut verträglich. Weitere endokrine Therapielinie bei Progress unter Aromataseinhibitoren, mögliche Thera-pieoption bei TNBC.