Projects
Search from 1158 projects:
1158 Project(s)
A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of AMG 334 in Migraine Prevention (ARISE-Study)
Jun 1, 2015To evaluate the effect of AMG 334 compared to placebo on the change from baseline in monthly migraine days, in subjects with episodic migraine
Clinical Studies - Jun 1, 2015 - Dec 31, 2017
Automatically Closed
Project leader: Flügel Dominique
Members: Zieglgänsberger Dominik, Müller Anna
Outcome after operative treatment of intra-articular calcaneal fractures
May 15, 2015Among all the bones in the foot the calcaneus is the most commonly fractured one, counting for 1 – 2% of all fractures. Calcaneus fractures are very complex injuries with regard to the damage of the bone, the cartilage of the subtalar joint and the s...
Clinical Studies - May 15, 2015 - Dec 31, 2016
Automatically Closed
Project leader: Schirm Andreas
aSCore: LONG-TERM EXPERIENCE WITH ABATACEPT SC IN ROUTINE CLINICAL
May 6, 2015STUDY DESIGN Overview of Study Design This is a non-interventional, multicenter, study consisting of 2 prospective cohorts of patients diagnosed with moderate to severe active RA and initiated/treated with abatacept SC. In some countries, patients ca...
Clinical Studies - May 6, 2015 - Oct 6, 2017
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia, Schmidig Kathrin, Bartz-Batliner Mira, Hutz Carina Liane
A phase III, open-label, multicenter, randomized study to investigate the efficacy and safety of MPDL3280A (ANTI−PD-L1 ANTIBODY) compared with chemotherapy in patients with locally advanced or metastatic urothelial bladder cancer after failure with platinum-containing chem-otherapy. GO29294
Apr 2, 2015Dies ist eine globale, multizentrische, offene, zweiarmige, randomisierte, kontrollierte Phase-III Studie zur Beurteilung der Wirksamkeit und Sicherheit von MPDL3280A im Ver-gleich mit Chemotherapie bei Patienten mit lokal fortge-schrittenem oder met...
Clinical Studies - Apr 2, 2015 - Dec 1, 2016
Automatically Closed
Project leader: Gillessen Sommer Silke
Members: Templeton Arnoud, Rothermundt Christian, Omlin Aurelius, Desax Marie-Claire
Evaluation and verification of serological activity markers in systemic lupus erythematosus
Apr 1, 2015Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease. So far, there is little evidence for the existence of specific biologic markers reliably indicating clinical activity and a rather wide panel of unspecific markers indica...
Fundamental Research - Apr 1, 2015 - Mar 31, 2018
Automatically Closed
Project leader: von Kempis Johannes
Members: Schmiedeberg Kristin
Modeling human neurodegenerative disease by iPS cell-derived neurons
Apr 1, 2015Gewinnung von kutanen Stammzellen mittels Stanzbiopsie bei Patienten mit genetischer amyotropher Lateralsklerose sowie asymptomatischen Angehörigen mit und ohne Mutationsnachweis.
Fundamental Research - Apr 1, 2015 - Dec 31, 2017
Completed
Project leader: Weber Markus
Improving the activity of proteasome inhibitors for potential treatment of
Mar 31, 2015Traditional chemotherapy fails to cure renal cell carcinoma (RCC), hence novel approaches and mechanisms need to be exploited.Proteotoxic stress-induced apoptosis can be induced in cancer cells by interfering with the homeostasis of protein biosynthe...
Fundamental Research - Mar 31, 2015 - Dec 7, 2018
Automatically Closed
Project leader: Abt Dominik
Members: Engeler Daniel, Driessen Christoph, Kraus Marianne, Bader Jürgen
OPTIMIS - Beobachtung der Behandlung mit oder ohne Nexavar von Patienten mit HCC nach erfolgter TACE und des Einschlusses des zeitlichen Beginns der nexavartherapie
Mar 30, 2015
Clinical Studies - Mar 30, 2015 - Sep 30, 2017
Completed
Members: Alfter Christine, Bernsmeier Christine, Künzler-Heule Patrizia, Semela David
Nutzen der wiederholten transkraniellen Doppler-Mikroemboliedetektion beim akuten ischämischen Schlaganfall
Mar 30, 2015Der Schlaganfall ist die zweithäufigste Todesursache und die häufigste Ursache einer erworbenenBehinderung im Erwachsenenalter. Für die meisten Patienten ist eine effiziente Sekundärprophylaxe die wirksamste Prävention um die Häufigkeit von Schlaganf...
Clinical Studies - Mar 30, 2015 - Mar 31, 2016
Completed
Project leader: Kägi Georg
Members: Vehoff Jochen
Abbvie M14-423 An Open Label, Multicenter Study to Evaluate Long-Term Outcomes With ABT-450/Ritonavir/ABT-267 and ABT-333 With or Without Ribavirin in Adults With Genotyp 1 Chronic Hepatitis C Infection
Mar 26, 2015
Clinical Studies - Mar 26, 2015 - Mar 31, 2020
Automatically Closed
Project leader: Semela David
Members: Bernsmeier Christine, Künzler-Heule Patrizia, Stillhard Roman
SENIOR
Mar 26, 2015Kurzzeitige duale Thrombozytenaggregationshemmer-Therapie mit Everolimus freisetzenden Stents Synergy® II bei Patienten über 75 Jahren, die eine perkutane Koronarrevaskularisierung erhalten. Ziele: Nachweis der Wirksamkeit und Sicherheit der Everol...
Clinical Studies - Mar 26, 2015 - Nov 30, 2018
Completed
Project leader: Weilenmann Daniel
Members: Schneider Irene
PneumRx CLN0014 - Europäisches RePneu Register
Mar 24, 2015Register-Studie Emphysema
Clinical Studies - Mar 24, 2015 - Mar 24, 2017
Aborted
Project leader: Schneider Tino
Members: Brutsche Martin, Kapfer Sarah, Schlotter Sandra
LONGACT study
Mar 24, 2015A prospective multicenter study to assess the coreelation of LONGterm wrist ACTigraphy recorded physical Performance and 6-minute walk distance in patients with pulmonary arterial Hypertension newly initiating endothelin receptor antagonist therapy
Clinical Studies - Mar 24, 2015 - Mar 24, 2015
Aborted
Project leader: Brutsche Martin
Members: Baty Florent, Kapfer Sarah, Schlotter Sandra, Schoch Otto
HOVON 103 / SAKK 30/10 protocol Tosedostat
Mar 19, 2015A randomized phase II multicenter study with a safety run-in to assess the tolerability and efficacy of the addition of oral tosedostat to standard induction therapy in AML and high risk myelodysplasia (MDS) (IPSS-R risk score > 4.5) in patients aged...
Clinical Studies - Mar 19, 2015 - Mar 19, 2015
Automatically Closed
Project leader: Hess Urs
Members: Hitz Felicitas, Baumann Michael, Driessen Christoph, Fehr Martin, Silzle Tobias
SAKK 23/13 Impact of a Surgical Sealing Patch on Lymphatic Drainage after Axillary Lymph Node Dissection for Breast Cancer. A Multicenter Randomized Phase III Trial
Mar 12, 2015Mit 5500 Neuerkrankungen im Jahr ist Brustkrebs mit Abstand die häufigste Krebserkrankung bei Schweizer Frauen. Fast 30% der Krebserkrankungen bei Frauen betreffen die Brust und Brustkrebs ist verantwortlich für rund 1350 Todesfälle pro Jahr. Schätz...
Clinical Studies - Mar 12, 2015 - Aug 27, 2017
Automatically Closed
Project leader: Chiesa Federica
Members: Knauer Michael
Predictive Swallowing Score (PRESS)
Mar 1, 2015We have developed the Predictive Swallowing Score (PRESS) - an easily applicable prognostic risk score of impaired oral intake after stroke. The 10 point score is calculated after the initial swallowing evaluation in the first days after stroke and s...
Clinical Studies - Mar 1, 2015 - Dec 31, 2016
Automatically Closed
Project leader: Kägi Georg
Members: Galovic Marian, Leisi Natascha, Müller Marlise, Stöckli Sandro, Arnold Marcel, Lyrer Philippe, Kahles Timo
Abbvie M 14-347
Mar 1, 2015A Multicenter, Open-Label Study to Evaluate the Long Term Efficacy, Safety, and Tolerability of Repeated Administration of Adalimumab in Subjects with Crohn's Disease
Clinical Studies - Mar 1, 2015 - Dec 1, 2017
Completed
Project leader: Borovicka Jan
Members: Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
Abbvie M14-033
Mar 1, 2015A Double-Blind, Randomized, Multicenter Study of Higher Versus Standard Adalimumab Dosing Regimens for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis This Phase 3 study design includes a Screening...
Clinical Studies - Mar 1, 2015 - Feb 1, 2018
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
ALERT
Feb 28, 2015VAlidation of an 8-‐item-‐questionnaire predictive for a positive CaLprotectin tEst and Real-‐life implemenTation in primary care to reduce diagnostic delay in inflammatory bowel disease
Clinical Studies - Feb 28, 2015 - Jan 30, 2017
Completed
Project leader: Borovicka Jan
Members: Dora Barbara, Sulz Michael
Telehealthcare in COPD - a Feasibility Trial
Feb 1, 2015The objective is to establish telehealthcare as an integrated, web-based treatment network between patient, GP and hospital to optimise care for COPD patients according to the GOLD-guidelines, assisted by simple-to-use, network-based gadgets (via sma...
Clinical Studies - Feb 1, 2015 - Feb 1, 2016
Completed
Project leader: Brutsche Martin
Members: Baty Florent, Dusemund Frank