Projects
Search from 1158 projects:
1158 Project(s)
Biofilms on short-term indwelling ureteral stents: Influence on associated symptoms and complications; Prediction by urine analysis; Current bacterial spectrum and antibiotic resistance
Oct 10, 2015Die Einlage von Harnleiterschienen ist im urologischen Alltag unverzichtbar. Sie ist jedoch mit erheblichen Beschwerden und Komplikationen verbunden. Die Möglichkeiten diese zu reduzieren sind beschränkt. Mit zunehmender Einlagedauer von Harnleitersc...
Clinical Studies - Oct 10, 2015 - Feb 10, 2018
Automatically Closed
Project leader: Abt Dominik
Members: Zumstein Valentin, Betschart Patrick, Qun Ren, Buhmann Matthias, Schmid Hans-Peter, Engeler Daniel, Albrich Werner
Biomarkers, Blood Pressure and BIS: Perioperative risk stratification and management optimization of patients at cardiac risk undergoing major noncardiac surgery (The BBB Study)
Oct 1, 2015Hintergrund und Motivation für die Studie Kardiovaskuläre Ereignisse (major adverse cardiovascular events, MACE) sind eine häufige Ursache perioperativer Morbidität und Mortalität nach grossen nichtherzchirurgischen Operationen. Sowohl die ACC/AHA al...
Clinical Studies - Oct 1, 2015 - Dec 31, 2018
Completed
Project leader: Filipovic Miodrag
European Cardiac Resynchronization Therapy (CRT) survey II registry
Oct 1, 2015It`s a snapshot survey initiated by the European Heart Rhythm Association and the Heart Failure Association, which is designed to describe clinical practice regarding implantation of CRT devices in a broad sample of hospitals. The clinical and demog...
Clinical Studies - Oct 1, 2015 - Dec 31, 2016
Completed
Project leader: Ammann Peter
Members: Schneider Irene
Cardiopulmonary- and hemodynamic responses during positive and negative airway pressure in patients with chronic obstructive pulmonary disease
Oct 1, 2015The overall aim of the present study is to investigate if positive and negative airway pressure influences cardiopulmonary- and hemodynamic responses by adding resistive loads or/and conducting NPPV throughout the entire breathing cycle in patients w...
Fundamental Research - Oct 1, 2015 - Aug 1, 2016
Automatically Closed
Project leader: Baty Florent, van Gestel Arnoldus, Brutsche Martin
Role of activated fibroblastic stromal cells in relapsing-remitting experimental autoimmune encephalomyelitis
Oct 1, 2015Multiple Sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) resulting in demyelination, axonal loss and consequential clinical impairment. In addition, the presence of meningeal inflammatory infiltrates in the progressive M...
Fundamental Research - Oct 1, 2015 - Nov 1, 2016
Automatically Closed
Project leader: Ludewig Burkhard
Members: Pikor Natalia
Blockade der Fibroblastenreifung zum Schutz vor autoimmuner Sehnerventzündung
Oct 1, 2015Optikusneuritis (Neuritis nervi optici, NNO) ist eine akute Entzündung des Sehnervs, die mit Symptomen wie Augenschmerzen und partiellem oder komplettem Sehverlust einhergeht. Die meisten Fälle der NNO sind auf multiple Sklerose (MS) als Grunderkrank...
Fundamental Research - Oct 1, 2015 - Sep 30, 2016
Automatically Closed
Project leader: Ludewig Burkhard
Members: Cupovic Jovana
Impact of omental fibroblastic stromal cells on the induction of anti-bacterial immunity
Oct 1, 2015Adaptive immune responses are induced within secondary lymphoid organs (SLOs) such as lymph nodes, spleen and Peyer’s patches. Structure and compartmentalization of SLOs is determined by fibroblastic stromal cells which built and maintain specialized...
Fundamental Research - Oct 1, 2015 - Sep 30, 2016
Automatically Closed
Project leader: Ludewig Burkhard
Members: Pérez Shibayama Christian Ivan, Mörbe Urs
Combination of ibrutinib and bortezomib followed by ibrutinib maintenance to treat patients with relapsed and refractory mantle cell lymphoma; a multicenter Phase I/II trial
Sep 9, 2015Das Mantelzelllymphom zeichnet sich durch eine für B-Zell Lymphome vergleichsweise schlechte Prognose aus. Dies erklärt sich durch häufige Rückfälle und dem meist ausgedehnten Krankheitsstadium und höherem Alter (median 60-65 Jahre) bei Diagnosestell...
Clinical Studies - Sep 9, 2015 - Mar 31, 2021
Automatically Closed
Project leader: Driessen Christoph
Members: Hitz Felicitas, Fehr Martin, Hess Urs, Hess Dagmar, Silzle Tobias
Kalydeco
Sep 1, 2015
Clinical Studies - Sep 1, 2015 - Sep 1, 2017
Automatically Closed
Project leader: Schoch Otto
Members: Finger Rebekka, Brutsche Martin, Kapfer Sarah, Schlotter Sandra
Ontogeny and functional characterization of splenic fibroblastic reticular cells (FRCs) and their mesenchymal precursors during homeostasis, immune-activation and infection
Sep 1, 2015Secondary lymphatic organs (SLOs) such as the spleen provide specialized microenvironmental niches for the development and control of immune responses. Particular mesenchymal stromal cells known as fibroblastic reticular cells (FRCs) generate distinc...
Fundamental Research - Sep 1, 2015 - Aug 31, 2018
Automatically Closed
Project leader: Ludewig Burkhard
Members: Cheng Hung-Wei
Eribulin as 1st line treatment in elderly patients (≥ 70 years) with advanced breast cancer: a multicenter phase II trial
Aug 11, 2015Es wird die Wirksamkeit und die Verträglichkeit von Eribulin als palliative Erstlinien-Chemotherapie bei älteren Brustkrebspatientinnen ((≥ 70 J.) untersucht. Es soll gezeigt werden, dass eine gegenüber den Registrierungs-Studien leicht reduzierte St...
Clinical Studies - Aug 11, 2015 - Jun 30, 2019
Automatically Closed
Project leader: Hasler-Strub Ursula
Members: Thürlimann Beat, Ruhstaller Thomas, Riniker Salome, Weder Patrik, Schmid Sabine, Magayakalbermatten N
SpA: AIN 457F2320
Aug 5, 2015A randomized, double-blind, placebo-controlled, phase III multicenter study of subcutaneous secukinumab (150 mg) with and without a subcutaneous loading regimen to assess efficacy, safety, and tolerability up to 2 years in patients with active ankylo...
Clinical Studies - Aug 5, 2015 - Aug 16, 2018
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia, Bartz-Batliner Mira, Hutz Carina Liane, Schmidig Kathrin
Erforschung von Frailty und milden kognitiven Beeinträchtigungen in erwachsenen Nierentransplantationspatienten zur Verbesserung der Risikovorhersage in Bezug auf klinische, psychosoziale, und gesundheitsökonomische Ergebnisse
Aug 4, 2015Es wird untersucht, ob erwachsene Nierentransplantationspatienten Symptome von körperlicher Gebrechlichkeit oder milde Gedächtnisveränderungen aufweisen. Gebrechliche Personen haben eine reduzierter Leistungsfähigkeit und eine vermehrte Anfälligkeit...
Clinical Studies - Aug 4, 2015 - Feb 1, 2022
Automatically Closed
Project leader: Binet Françoise-Isabelle
CaCo: Does caffeine intake reduce postoperative bowel paralysis after elective laparoscopic colectomy? - A randomized placebo controlled trial
Aug 1, 2015Background Postoperative bowel paralysis is common after abdominal operations, including colectomy. As a result, hospitalization may be prolonged leading to increased cost. A recent randomized controlled trial from the University of Heidelberg showed...
Clinical Studies - Aug 1, 2015 - Jul 31, 2022
Automatically Closed
Project leader: Steffen Thomas
Members: Mueller Sascha, Beutner Ulrich, Luethi Cornelia, Warschkow Rene, Tarantino Ignazio, Brunner Walter, Marti Lukas
Next Generation Sequencing-enabled Diagnostics as a Cornerstone for Personalized (Nano-)Medicine
Jul 9, 2015
Fundamental Research - Jul 9, 2015 - Jul 9, 2016
Completed
Project leader: Jochum Wolfram
An open-label, multicohort, phase II study of MPDL3280A in advanced solid tumors
Jul 8, 2015MO29518 ist eine offene, multizentrische, multinationale Phase-II-Studie mit 10 Kohorten, welche MPDL3280A (Anti-PD-L1 Antikörper) bei Patienten mit fortgeschrittenen soliden Tumoren untersucht (Gebärmutterhalskrebs, Nasen-Rachenkrebs, spezielle Art...
Clinical Studies - Jul 8, 2015 - Jul 31, 2019
Automatically Closed
Project leader: Gillessen Sommer Silke
Members: Schmid Sabine, Fischer Stefanie, Rothermundt Christian, Templeton Arnoud, Omlin Aurelius, Desax Marie-Claire, Früh Martin, Weisshaupt Christian
Cardiopulmonary- and hemodynamic responses during positive and negative airway pressure in patients with chronic obstructive pulmonary disease (COPD)
Jul 1, 2015The overall aim of the present study is to investigate if positive and negative airway pressure influences cardiopulmonary- and hemodynamic responses by adding resistive loads or/and conducting NPPV throughout the entire breathing cycle in patients w...
Fundamental Research - Jul 1, 2015 - Mar 1, 2016
Automatically Closed
Project leader: van Gestel Arno Jr
Members: Baty Florent, Brutsche Martin
GA289103/Gardenia
Jun 28, 2015GA29103: PHASE III, RANDOMIZED, MULTICENTER DOUBLE-BLIND, DOUBLE-DUMMY STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ETROLIZUMAB COMPARED WITH INFLIXIMAB IN PATIENTS WITH MODERATE TO SEVERE ACTIVE ULCERATIVE COLITIS WHO ARE NAIVE TO TNF INHIBITORS
Clinical Studies - Jun 28, 2015 - Jun 28, 2020
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Sulz Michael, Semadeni Gian-Marco
Effect of counselling during pulmonary rehabilitation on self-determined motivation towards physical activity in patients with Chronic Obstructive Pulmonary Disease
Jun 15, 2015The overall aim of the present study is to investigate if a PA counselling program during PR increases PA level in daily life in patients with COPD.
Fundamental Research - Jun 15, 2015 - Jan 31, 2017
Automatically Closed
Project leader: van Gestel Arno Jr
Members: Rausch Osthoff Anne-Kathrin, Baty Florent, Hess Thomas
Characterizing sleep apnea by using a wearable electro EMPA cardiogram device
Jun 1, 2015The primary aim of the present study is to analyze the validity and feasibility of a wearable ECG Acquisition System (EMPA) by comparing standard measures of heart rate variability (Low-frequency power, LF) with those of polysomnography.
Fundamental Research - Jun 1, 2015 - Dec 1, 2016
Automatically Closed
Project leader: Brutsche Martin
Members: Baty Florent, van Gestel Arnoldus, Rossi Rene, Annaheim Simon, Weder Markus, Schoch Otto