Projects

Diese Studie dient der Erforschung der Wirksamkeit und Sicherheit von Finineron in Ergänzung zur Standardtherapie im Hinblick auf eine Reduktion der kardiovaskulären Morbidität und Mortalität bei Patienten mit Diabetes mellitus Typ 2 mit der klinisch...

Clinical Studies - Jun 1, 2016 - Mar 31, 2021

Completed

Project leader: Bilz Stefan
Members: Jenni Vera, Dehos Barbara, Räss Andrea

Research project in which biological material is sampled from humans and health-related personal data is collected for research.

Clinical Studies - Jun 1, 2016 - Sep 14, 2022

Automatically Closed

Project leader: Semela David
Members: Stillhard Roman

The​ ​ aim​ ​ of​ ​ this​ ​ exploratory​ ​ study​ ​ is​ ​ to​ ​ assess​ ​ the​ ​ prevalence​ ​ and​ ​ the​ ​ functional​ ​ role​ ​ of RTFTs​ ​ in​ ​ lung​ ​ cancer.​ ​ Total​ ​ RNA​ ​ extracted​ ​ from​ ​ lung​ ​ biopsies​ ​ obtained​ ​ in​ ​ 50​ ​ p...

Fundamental Research - Jun 1, 2016 - Dec 31, 2018

Automatically Closed

Project leader: Baty Florent
Members: Brutsche Martin

The AdaptResponse study is a prospective, randomized, controlled, interventional, single-blinded, multi-center, post-market, global Cardiac Resynchronization Therapy (CRT) in heart failure (HF) clinical study. The purpose of this clinical study is...

Clinical Studies - May 30, 2016 - Dec 31, 2022

Completed

Project leader: Ammann Peter
Members: Vetsch Susanne

Each subject will participate in the trial from the time the subject signs the Informed Consent Form (ICF) through the final contact. After a screening phase of up to 42 days, eligible subjects can be randomized to either pembrolizumab (experimental...

Clinical Studies - May 27, 2016 - Nov 30, 2020

Automatically Closed

Project leader: Weisshaupt Christian

The current standard of care for patients with metastatic castration resistant prostate cancer (mCRPC) and dis-ease progression is either treatment with abiraterone acetate and prednisone in asymptomatic or mildly symp-tomatic patients without viscer...

Clinical Studies - May 20, 2016 - Jul 31, 2026

Ongoing

Project leader: Rothermundt Christian

Clinical Studies - May 15, 2016 - Jan 15, 2019

Automatically Closed

Project leader: Dick Florian
Members: von Allmen Regula, Beutner Ulrich, Luethi Cornelia, Hechelhammer Lukas, Benecke Ulf, Poloczek Alexander

Die endoskopische Vollwandresektion (endoscopic full thickness resection: EFTR) ist ein neuer therapeutischer und/oder diagnostischer Ansatz zur Behandlung von konventionell endoskopisch nicht angehbarer kolorektaler Neoplasien. Diese neue Technik...

Clinical Studies - May 13, 2016 - May 13, 2020

Completed

Project leader: Baumeler Stephan

A Randomized, Double-Blind, Placebo-Controlled Phase II Study to Investigate the Efficacy and Safety of Riociguat in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc) Evaluierung der Wirksamkeit und Sicherheit einer 52-wöchigen Behandlung m...

Clinical Studies - May 13, 2016 - Apr 28, 2019

Completed

Project leader: Müller Rüdiger
Members: Forrer Silvia, Bartz-Batliner Mira, Hutz Carina Liane, Schmidig Kathrin

A randomised controlled, international, multicentre crossover trial. We want to test, whether telehealthcare can improve HRQOL and reduce emergency admissions and hospitalisations due to AECOPD.

Clinical Studies - May 11, 2016 - Dec 31, 2018

Automatically Closed

Project leader: Brutsche Martin
Members: Baty Florent, Rassouli Frank, Schlotter Sandra

The aim of the retrospective research project is to analyze hardware characteristics (impulse generator and lead manufacturer, battery technology, lead design), implantation techniques and clinical factors associated with reoperations. Primary endpo...

Clinical Studies - May 9, 2016 - May 31, 2018

Completed

Project leader: Ammann Peter
Members: Schneider Irene

Es handelt sich um eine zweistufige Phase-I-Studie. Stufe 1 der Studie dient der Bestimmung der MTD, der Identifika-tion der empfohlenen Stufe-II-Dosierung sowie der Ermitt-lung der optimalen Infusionsdauer. Stufe 2 dient der Bestä-tigung der Sicherh...

Clinical Studies - May 4, 2016 - Jan 1, 2018

Automatically Closed

Project leader: Driessen Christoph

To assess the long-term safety and efficacy of the Xposition S stent (self-expanding sirolimus-eluting stent with a durable polymer coating) in the treatment of unprotected left main coronary artery disease. Primary clinical endpoint: Target Lesion...

Clinical Studies - May 2, 2016 - Dec 31, 2019

Completed

Project leader: Weilenmann Daniel
Members: Schneider Irene

In dieser Studie sollen neue Methoden zur Messung von ALS-Symptomen während des Verlaufs der Erkrankung beobachtet werden, um festzustellen, ob mit diesen neuen Ansätzen Veränderungen besser erkannt werden können als mit den derzeit verwendeten Metho...

Clinical Studies - May 1, 2016 - Jun 1, 2018

Automatically Closed

Project leader: Weber Markus
Members: Neuwirth Christoph, Burkhardt Christian, Sommer Helma

MPDL3280A ist ein humaner monoklonaler Antikörper der Immunglobulin (Ig)-Klasse G1 und wird in den Ovarialzellen des chinesischen Hamsters produziert. MPDL3280A wird als mögliche Therapie gegen solide Tumore und hämatologische Malignitäten in Mensche...

Clinical Studies - Apr 14, 2016 - Apr 14, 2020

Automatically Closed

Project leader: Früh Martin

The primary objectives of the study are to estimate and rank-order the longitudinal standardized mean changes over 6 months and over 12 months, for a set of outcome measures administered to participants with amyotrophic lateral sclerosis (ALS), in or...

Clinical Studies - Apr 2, 2016 - Aug 14, 2019

Completed

Project leader: Weber Markus
Members: Neuwirth Christoph

Study Hypothesis: In patients with evidence of device-detected sub-clinical atrial fibrillation (SCAF) and additional risk factors for stroke, treatment with apixaban compared with aspirin will reduce the risk of the composite of stroke and systemic...

Clinical Studies - Apr 1, 2016 - Jan 1, 2026

Completed

Project leader: Ammann Peter
Members: Gemperle Michaela, Brenner Roman, Fink Karin, Vetsch Susanne

Secondary lymphoid organs such as lymph nodes (LNs) and Peyer’s patches (PPs) sample antigens from the body’s inner and outer surfaces and mediate optimal interaction of immune cells. These functions rely on the presence of specialized microenvironme...

Fundamental Research - Apr 1, 2016 - Mar 31, 2019

Automatically Closed

Project leader: Ludewig Burkhard
Members: Mörbe Urs, Pérez Shibayama Christian Ivan

Primary/co-primary. To prospectively investigate whether adjuvant treatment with pembrolizumab after completion of radical surgery (lobectomy/pneumonectomy) with or with-out standard adjuvant chemotherapy for stage IB (T ≥ 4 cm) -II-IIIA NSCLC patien...

Clinical Studies - Mar 30, 2016 - Mar 30, 2020

Automatically Closed

Project leader: Früh Martin

A Multi-Country, Multicenter, Single-Arm, Open-Label Study to Document the Safety, Tolerability and Effect of Alirocumab on atherogenic lipoproteins in High Cardio-Vascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With...

Clinical Studies - Mar 16, 2016 - Jul 1, 2018

Completed

Project leader: Bilz Stefan
Members: Jenni Vera, Räss Andrea