Projects
Search from 1157 projects:
1157 Project(s)
ECARA
Jun 16, 2017Explore Clinical Utility of Evolocumab in Combination with an e-Health System: Swiss Prospective Observational Study in Patients with clinical Atherosclerotic Cardiovascular Disease (ASCVD) (ECARA)
Clinical Studies - Jun 16, 2017 - Dec 1, 2019
Completed
Project leader: Rickli Hans
Members: Gemperle Michaela
ETOP 10-16 BOOSTER: A randomised phase II trial of osimertinib and bevacizumab versus osimertinib alone as second-line treatment in stage IIIb-IVb NSCLC with con-firmed EGFRm and T790M
Jun 15, 2017First-generation EGFR tyrosine kinase inhibitors provide significant clinical benefit in patients with advanced EGFR-mutant (EGFRm) non–small cell lung carcinoma (NSCLC). However, all patients ultimately develop disease progres-sion, driven – as the...
Clinical Studies - Jun 15, 2017 - Oct 26, 2023
Automatically Closed
Project leader: Früh Martin
HD21 for advanced stages: Treatment optimization trial in the first-line treatment of advanced stage Hodgkin lymphoma; comparison of 6 cy-cles of escalated BEACOPP with 6 cycles of BrECADD
Jun 9, 2017With the establishment of polychemotherapy and the con-tinuous advancements in radiotherapy, Hodgkin lymphoma has meanwhile become a malignant oncological disease in adults with one of the best prognoses of all. The outcome improvements in Hodgkin ly...
Clinical Studies - Jun 9, 2017 - Sep 30, 2021
Automatically Closed
Project leader: Hitz Felicitas
Amiselimod
Jun 1, 2017A Phase 3, Randomized, Double-Blinded, Placebo-Controlled, Multicenter Study of Amiselimod (MT-1303) in the Induction and Maintenance of Clinical Response and Remission in Subjects With Moderate to Severe Ulcerative Colitis
Clinical Studies - Jun 1, 2017 - Sep 27, 2022
Automatically Closed
Members: Knellwolf Christina, Dora Barbara, Krieger-Grübel Claudia, Sulz Michael
Swiss Pituitary Registry
Jun 1, 2017Prospektive Erfassung aller endoskopisch operierten Hypophysentumore SwissPit
Clinical Studies - Jun 1, 2017 - Jun 1, 2021
Automatically Closed
Project leader: Bilz Stefan
Members: Ebert Andrea, Räss Andrea
Coaching im Rahmen der Karriereplanung junger Ärztinnen und Ärzte
Jun 1, 2017Der vielbeschriebene Ärztemangel erfordert neue Konzepte, um die Transition von der Studienzeit in den Berufsalltag und die fachärztliche Weiterbildung gelingen zu lassen. Auch Coaching-Angebote für junge Ärztinnen und Ärzte können in diesem Zusammen...
Healthcare Research - Jun 1, 2017 - Dec 31, 2021
Completed
Project leader: Thanner Mirjam
Members: Winder Franziska, Quenzer Anne, Schlegel A, Von Szadkowski C, Hornung René
PARADISE-MI: Prospective ARNI versus ACE inhibitor trial to DetermIne
May 31, 2017A multi-center, randomized, double-blind, active-controlled, parallelgroup Phase 3 study to evaluate the efficacy and safety of LCZ696 compared to ramipril on morbidity and mortality in high risk patients following an acute myocardial infarction The...
Clinical Studies - May 31, 2017 - Mar 1, 2021
Completed
Project leader: Maeder Micha
Members: Gemperle Michaela
Finch 302 Gilead
May 24, 2017A Randomized, Double-blind, Placebo-controlled, Multicenter, Phase 3 Study to Assess the Efficacy and Safety of Filgotinib Administered for 24 weeks in Combination with Conventional Synthetic Disease-modifying Anti-rheumatic Drug(s) (csDMARDs) to Sub...
Clinical Studies - May 24, 2017 - Sep 26, 2018
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia, Hutz Carina Liane, Bartz-Batliner Mira, Schmidig Kathrin
CCX_Chemocentryx CL010 CCX168 (Avacopan)
May 15, 2017A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of CCX168 (Avacopan) in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)- Associated Vasculitis Treated Concomitantly with Rituximab or Cycloph...
Clinical Studies - May 15, 2017 - May 31, 2021
Completed
Project leader: Neumann Thomas
Members: Forrer Silvia, Hutz Carina Liane, Bartz-Batliner Mira, Rubbert-Roth Andrea
Exploring the Origins, Characteristics and Implications of Placental Calcification - A Materials Science Approach
May 1, 2017Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF), Abteilung Mathematik, Natur- und Ingenieurwissenschaften
Fundamental Research - May 1, 2017 - Apr 30, 2020
Automatically Closed
Project leader: Herrmann Inge
Members: Hornung René, Rduch Thomas, Neels Antonia, Bertazzo Sergio, Buerki-Thurnherr Tina
SAKK 19/16:Binimetinib, pemetrexed and cisplatin, followed by maintenance with binimetinib and pemetrexed, in patients with advanced non-small cell lung cancer with KRAS mutationsA multicenter phase IB trial
Apr 25, 2017There is a need for more effective therapies for patients with advanced NSCLC driven by the RAS/MEK/ERK pathway. These tumors are generally aggressive, are almost exclusively of non-squamous histology, and represent the largest group of patients with...
Clinical Studies - Apr 25, 2017 - Nov 30, 2019
Automatically Closed
Project leader: Früh Martin
Evaluation of High Resolution Endoscopy Compared to the High Resolution Anoscopy for Detection of Early Dysplastic or Neoplastic Lesions of the Anal Canal in High−Risk Patients
Apr 17, 2017There is a strong correlation between HPV infection and anal squamous cell cancer (SCC). Just like in nearly 100% of cervical cancer, infection with human papillomavirus (HPV) high-risk types causes more than 80% of anal cancer. Nevertheless the natu...
Clinical Studies - Apr 17, 2017 - Apr 17, 2019
Automatically Closed
Project leader: Baumeler Stephan
Members: Borovicka Jan, Maurus Christine
SAKK 35/15: A phase I trial of obinutuzumab in combination with venetoclax in previously untreated follicular lymphoma patients
Apr 3, 2017Follicular lymphoma is an indolent yet incurable lymphoma characterized by a relapsingremitting course with initial responses to standard therapies, invariably followed by shorter disease free intervals. In recent years, significant treatment improve...
Clinical Studies - Apr 3, 2017 - Sep 30, 2020
Automatically Closed
Project leader: Hitz Felicitas
Allergan AURORA
Apr 1, 2017A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Cenicriviroc for the Treatment of Liver Fibrosis in Adult Subjects with Nonalcoholic Steatohepatitis
Clinical Studies - Apr 1, 2017 - Jan 1, 2025
Aborted
Project leader: Semela David
NOSTONE
Apr 1, 2017randomisiert-kontrollierte doppelblinde Multicenter-Studie zur Evaluation von Hydrochlorothiazid in verschiedenen Dosierungen versus Placebo in der Rezidivprophylaxe bei Patienten mit rezidivierenden calciumhaltigen Nierensteinen Primärer Endpunkt d...
Clinical Studies - Apr 1, 2017 - Apr 1, 2021
Automatically Closed
SAKK PRODIGE 32: Systematic surgery vs monitoring and salvage surgery in opera-ble oesophageal cancer in complete clinical response after chemoradiation Strategic multicenter randomized phase II- III trial
Mar 28, 2017Patients with locally advanced oesophageal cancer are evaluable for a participation in this trial. The standard treatment for these patients is neoadjuvant chemoradia-tion followed by surgery. Patients receiving a complete pathological remission afte...
Clinical Studies - Mar 28, 2017 - Sep 30, 2024
Automatically Closed
Project leader: Ruhstaller Thomas
SAKK 41/16: Neoadjuvant treatment with Regorafenib and Capecitabine combined with radiotherapy in locally advanced rectal ca cer. A multicenter phase Ib trial (RECAP)
Mar 7, 2017Despite treatment of locally advanced rectal cancer re-lapses are frequent. Several attempts to improve these results with therapy intensification have shown modest effect on disease free survival (DFS) and overall survival (OS). Recent studies with...
Clinical Studies - Mar 7, 2017 - Jul 31, 2019
Automatically Closed
Project leader: Jörger Markus
GFT505-315
Mar 1, 2017A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of Elafibranor in Patients with Nonalcoholic Steatohepatitis (NASH) and fibrosis
Clinical Studies - Mar 1, 2017 - Nov 1, 2020
Aborted
Members: Stillhard Roman, Semela David
Schilddrüsenknoten-Register
Mar 1, 2017Elektronische Datenbank zur Erfassung von medizinischen Befunden, klinischen Untersuchungen und biologischem Material im Rahmen der Schilddrüsenknoten-Abklärung und Punktion
Clinical Studies - Mar 1, 2017 - Mar 1, 2021
Automatically Closed
Project leader: Bilz Stefan
Members: Räss Andrea
BIOBIO
Feb 14, 2017A Randomized, Multi-Center Biomarker Trial to Predict Therapeutic Responses of Patients with Rheumatoid Arthritis to a Specific Biologic Mode of Action
Clinical Studies - Feb 14, 2017 - Aug 16, 2018
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia, Hutz Carina Liane, Bartz-Batliner Mira, Schmidig Kathrin