Projects
Search from 1164 projects:
1164 Project(s)
PIONEER 7
Dec 8, 2017Eine Studie zur Untersuchung der Wirksamkeit und Sicherheit von oralem Semaglutid unter Verwendung einer flexiblen Dosisanpassung bei Patienten mit Typ 2 Diabetes Mellitus im Vergleich zu Sitagliptin
Clinical Studies - Dec 8, 2017 - Jul 31, 2019
Completed
Project leader: Bilz Stefan
Members: Drescher Tilman, Räss Andrea
Lilly RHCF SPIRIT
Oct 16, 2017A 52-Week Multicenter, Randomized, Open-Label, Parallel- Group Study Evaluating the Efficacy and Safety of Ixekizumab versus Adalimumab in Patients with Psoriatic Arthritis Who Are Biologic Disease-Modifying Anti-Rheumatic Drug Naive
Clinical Studies - Oct 16, 2017 - Oct 24, 2021
Completed
Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Forrer Silvia, Hutz Carina Liane, Neumann Thomas
A Phase 2, multi-center, open label study of NIR178 in combination with PDR001 in patients with selected ad-vanced solid tumors and non-Hodgkin lymphoma
Oct 5, 2017This is a multi-center, open label, phase 2 study to evaluate efficacy of the NIR178 and PDR001 combination in NSCLC, other solid tumors, and diffuse large B-cell lymphoma (DLBCL). The study has three parts: part 1: Multi-arm Bayesian adaptive signal...
Clinical Studies - Oct 5, 2017 - Feb 20, 2024
Automatically Closed
Project leader: Jörger Markus
Anal Mapping Biopsies for Human Papilloma Virus (HPV) Associated Lesions
Oct 4, 2017Es gibt keinen eindeutigen Goldstandard für die Diagnose von HPV-assoziierten Analläsionen. Die übliche Diagnostik erfolgt mittels hochauflösender Anoskopie (HRA). Die diagnostische Genauigkeit dieser Methode ist jedoch unklar und stark vom Prüfer ab...
Clinical Studies - Oct 4, 2017 - Feb 4, 2018
Completed
Project leader: Baumeler Stephan, Borovicka Jan, Marti Lukas
Members: Maurus Christine
Abbvie M15-572 Phase 3 PsA mit inadäquater Response auf bDMARD
Oct 2, 2017A Phase 3, Randomized, Double-Blind, Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Subjects with Active Psoriatic Arthritis Who Have a History of Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumat...
Clinical Studies - Oct 2, 2017 - Oct 3, 2024
Automatically Closed
Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Hutz Carina Liane, Neumann Thomas
SERVE - Effect of phosphodiesterase-5 inhibition with Tadalafil on SystEmic Right VEntricular size and function
Oct 1, 2017This study assesses in a pilot trial the effect of PDE-5 inhibition with Tadalafil on RV size and function, exercise capacity and neurohumoral activation in adults with a systemic RV over a 3-year follow-up period. Included patients: Adults (≥18 year...
Clinical Studies - Oct 1, 2017 - Jul 1, 2021
Completed
Project leader: Engel Reto
Members: Gemperle Michaela
Azithromycin for the treatment of cough in idiopathic pulmonary fibrosis
Oct 1, 2017Multi centre, prospective, randomized, double blind, 2 treatment, 2 period crossover study with two 12-week treatment periods separated by a 4 week drug-free washout period and a 4 week follow-up performed at the University Hospital Berne, Basel, Zür...
Clinical Studies - Oct 1, 2017 - Dec 1, 2018
Automatically Closed
Project leader: Brutsche Martin
Members: Finger Rebekka, Tschirren Ursina, Baty Florent, Widmer Sandra
SAKK 17/16: Lurbinectedin Monotherapy in Pa-tients with Progressive Malignant Pleural Mesothelioma. A Multicenter, Single-arm Phase II Trial
Sep 29, 2017Malignant mesothelioma arises from the mesothelial cells of the pleural, peritoneal or pericardial lining and is often associated with asbestos exposition (Robinson, 2005). There is no cure for most malignant mesotheliomas and the scope of all three...
Clinical Studies - Sep 29, 2017 - Sep 29, 2021
Automatically Closed
Project leader: Früh Martin
SAKK 08/15 PROMET
Sep 27, 2017PROMET - Multicenter, Randomized Phase II Trial of Salvage Radiotherapy +/- Metformin for Patients with Prostate Cancer after Prostatectomy The main objective of the trial is to explore the efficacy of SRT plus metformin compared to SRT in the endpo...
Clinical Studies - Sep 27, 2017 - Oct 7, 2030
Ongoing
Project leader: Putora Paul Martin
Members: Panje Cédric
Randomisierte, doppelblinde, placebokontrollierte Pha-se III-Studie zu Rovalpituzumab Tesirin als Erhaltungs-therapie nach einer Erstlinienchemotherapie auf Platin-basis bei Studienteilnehmern mit ausgebreitetem (exten-sive-stage) kleinzelligem Bronchialkarzinom (MERU)
Sep 22, 2017Industrie gesponserte Studie zur Evaluation der Wirksamkeit (hinsichtlich OS und PFS) von Rovalpituzumab Tesirin beim SCLC, eingesetzt als Erhaltungstherapie nach Erstli-nientherapie. Rovalpituzumab Tesirin ist ein Antikörper-Wirkstoff Konju-gat, wob...
Clinical Studies - Sep 22, 2017 - Mar 31, 2019
Automatically Closed
Project leader: Früh Martin
First Experiences with Screening of Anal Intraepithelial Neoplasia (AIN): a Single Center Retrospective Data-Analysis
Sep 1, 2017Hintergrund Zwischen Human Papilloma Virus (HPV) und Analkrebs besteht eine starke Korrelation. Wie beim Cervixkarzinom der Frau sind mehr als 80% der Analkarzinome durch HPV bedingt. Analkrebs geht meist aus Vorläuferläsionen, den analen intraepithe...
Clinical Studies - Sep 1, 2017 - Sep 2, 2018
Automatically Closed
Project leader: Baumeler Stephan
Members: Maurus Christine, Marti Lukas, Borovicka Jan, Bock Susanne, Bischofberger Stephan, Schmid Patrick
ECARA
Sep 1, 2017Beobachtungsstudie Exploration des klinischen Nutzens von Evolocumab in Kombination mit einem e-Health-System: Schweizerische prospektive Beobachtungsstudie an Patienten mit klinisch manifester atherosklerotischer Herz-Kreislauf-Erkrankung (ASCVD) (E...
Clinical Studies - Sep 1, 2017 - Dec 31, 2018
Completed
Project leader: Bilz Stefan
Members: Dehos Barbara, Räss Andrea
Early versus Late initiation of direct oral Anticoagulants in post-ischaemic stroke patients with atrial fibrillatioN (ELAN): an international, multicentre, randomised-controlled, two-arm, assessor-blinded trial
Aug 31, 2017Inhalt und Ziele des Forschungsprojektes Ein Hirnschlag kann durch ein Vorhofflimmern des Herzens (das heisst unregelmässiger Herzrhythmus) ausgelöst werden. Patienten mit einem solchen Hirnschlag sind einem erhöhten Risiko ausgesetzt weitere Hirnsch...
Clinical Studies - Aug 31, 2017 - Jul 31, 2021
Automatically Closed
Project leader: Vehoff Jochen, Kägi Georg
GA29145
Aug 28, 2017AN OPEN-LABEL EXTENSION AND SAFETY MONITORING STUDY OF PATIENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN’S DISEASE PREVIOUSLY ENROLLED IN THE ETROLIZUMAB PHASE III PROTOCOL GA29144
Clinical Studies - Aug 28, 2017 - Aug 28, 2021
Automatically Closed
Project leader: Borovicka Jan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
The MENAC Trial - A randomised, open-label trial of a multimodal intervention (multimodal = exercise, nutrition and anti-inflammatory medication) versus standard care in cancer patients with cachexia
Aug 24, 2017Cachexia is a common detrimental consequence of cancer limiting therapy, quality of life and survival. There is no standard treatment available and its complex multifactorial pathophysiology requires multimodal treatment. Based on promising phase II...
Clinical Studies - Aug 24, 2017 - May 31, 2020
Automatically Closed
Project leader: Strasser Florian, Domeisen Benedetti Franzisca
Members: Attoun-Knobel Suzanne, Behnke Nadine
TICH-NOAC (Treatment of intracerebral hemorrhage in patients on non-vitamin K oral anticoagulants with tranexamic acid
Aug 22, 2017Neue, direkte, nicht Vitamin-K antagonisierende orale Antikoagulantien (NOAC oder DOAC) sind wirksame Medikamente zur Prophylaxe und Behandlung einer Vielzahl von thrombembolischen Erkrankungen wie zum Beispiel der Hirnschlagprophylaxe bei Patienten...
Clinical Studies - Aug 22, 2017 - Dec 31, 2019
Automatically Closed
Project leader: Kägi Georg
Members: Vehoff Jochen
An open-label, single arm study to evaluate the effectiveness and safety of Ocrelizumab in patients with early stage relapsing remitting Multiple Sclerosis
Aug 14, 2017Ziel der Studie ist es herauszufinden, ob Ocrelizumab (das Prüfpräparat) die Verschlechterung der Anzeichen und Symptome Ihrer Multipler Sklerose (MS) im Frühstadium zum Stillstand bringt.
Clinical Studies - Aug 14, 2017 - Dec 31, 2021
Automatically Closed
GA29144/Bergamot
Aug 1, 2017A PHASE III, RANDOMIZED, DOUBLEBLIND, PLACEBOCONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ETROLIZUMAB AS AN INDUCTION AND MAINTENANCE TREATMENT FOR PATIENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN’S DISEASE
Clinical Studies - Aug 1, 2017 - Aug 1, 2021
Automatically Closed
Project leader: Borovicka Jan, Brand Stephan
Members: Dora Barbara, Frei Remus, Knellwolf Christina, Semadeni Gian-Marco, Sulz Michael
ICL670, Deferasirox
Aug 1, 2017A phase II, multicenter, open-label, randomized two-year study to evaluate the efficacy and safety of deferasirox film-coated tablet versus phlebotomy in patients with Hereditary Hemochromatosis
Clinical Studies - Aug 1, 2017 - Jan 1, 2020
Completed
Project leader: Semela David
Members: Stillhard Roman
LEADERS FREE III
Aug 1, 2017A study evaluating the safety and efficacy of the BioFreedomTM Biolimus A9TM coated Cobalt Chromium coronary stent system in patients at high risk of bleeding. The objective of this study is to evaluate if the BioFreedomTM CoCr Drug Coated stent has...
Clinical Studies - Aug 1, 2017 - Dec 31, 2021
Completed
Project leader: Weilenmann Daniel
Members: Vetsch Susanne