Projects
Search from 1164 projects:
1164 Project(s)
Allergan AURORA
Apr 1, 2017A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Cenicriviroc for the Treatment of Liver Fibrosis in Adult Subjects with Nonalcoholic Steatohepatitis
Clinical Studies - Apr 1, 2017 - Jan 1, 2025
Aborted
Project leader: Semela David
NOSTONE
Apr 1, 2017randomisiert-kontrollierte doppelblinde Multicenter-Studie zur Evaluation von Hydrochlorothiazid in verschiedenen Dosierungen versus Placebo in der Rezidivprophylaxe bei Patienten mit rezidivierenden calciumhaltigen Nierensteinen Primärer Endpunkt d...
Clinical Studies - Apr 1, 2017 - Apr 1, 2021
Automatically Closed
SAKK PRODIGE 32: Systematic surgery vs monitoring and salvage surgery in opera-ble oesophageal cancer in complete clinical response after chemoradiation Strategic multicenter randomized phase II- III trial
Mar 28, 2017Patients with locally advanced oesophageal cancer are evaluable for a participation in this trial. The standard treatment for these patients is neoadjuvant chemoradia-tion followed by surgery. Patients receiving a complete pathological remission afte...
Clinical Studies - Mar 28, 2017 - Sep 30, 2024
Automatically Closed
Project leader: Ruhstaller Thomas
SAKK 41/16: Neoadjuvant treatment with Regorafenib and Capecitabine combined with radiotherapy in locally advanced rectal ca cer. A multicenter phase Ib trial (RECAP)
Mar 7, 2017Despite treatment of locally advanced rectal cancer re-lapses are frequent. Several attempts to improve these results with therapy intensification have shown modest effect on disease free survival (DFS) and overall survival (OS). Recent studies with...
Clinical Studies - Mar 7, 2017 - Jul 31, 2019
Automatically Closed
Project leader: Jörger Markus
GFT505-315
Mar 1, 2017A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of Elafibranor in Patients with Nonalcoholic Steatohepatitis (NASH) and fibrosis
Clinical Studies - Mar 1, 2017 - Nov 1, 2020
Aborted
Members: Stillhard Roman, Semela David
Schilddrüsenknoten-Register
Mar 1, 2017Elektronische Datenbank zur Erfassung von medizinischen Befunden, klinischen Untersuchungen und biologischem Material im Rahmen der Schilddrüsenknoten-Abklärung und Punktion
Clinical Studies - Mar 1, 2017 - Mar 1, 2021
Automatically Closed
Project leader: Bilz Stefan
Members: Räss Andrea
BIOBIO
Feb 14, 2017A Randomized, Multi-Center Biomarker Trial to Predict Therapeutic Responses of Patients with Rheumatoid Arthritis to a Specific Biologic Mode of Action
Clinical Studies - Feb 14, 2017 - Aug 16, 2018
Completed
Project leader: Müller Rüdiger
Members: Forrer Silvia, Hutz Carina Liane, Bartz-Batliner Mira, Schmidig Kathrin
WIN: Worldwide registry to assess the STENTYS XPOSITION S for revascularization of coronary arteries In routine cliNical practice
Jan 27, 2017To assess the long term safety and efficacy of the XPOSITION S STENT in routine clinical practice. Inclusion of subjects with coronary artery disease, including patients with chronic stable angina, silent ischemia and acute coronary syndrome, who qua...
Clinical Studies - Jan 27, 2017 - Jan 31, 2020
Completed
Project leader: Weilenmann Daniel
Members: Schneider Irene
Dissecting the association of the human palatine tonsil microbiome and HPV-driven oropharyngeal squamous cell carcinoma
Jan 1, 2017Oropharyngeal squamous cell carcinoma (OPSCC) can be caused by viral transformation of epithelial cells in the oropharynx such as high risk-human papilloma virus (HR-HPV). Importantly, the incidence of OPSCC has been increasing during the last decade...
Fundamental Research - Jan 1, 2017 - Dec 31, 2018
Automatically Closed
Project leader: Ludewig Burkhard
Members: Broglie Däppen Martina, Stöckli Sandro, Cupovic Jovana
M14-533
Jan 1, 2017A Phase 3 Multicenter, Long-Term Extension Study to Evaluate the Safety and Efficacy of Upadacitinib (ABT-494) in Subjects with Ulcerative Colitis
Clinical Studies - Jan 1, 2017 - Dec 1, 2022
Automatically Closed
Project leader: Sulz Michael
Members: Smolders Jolijn, Brand Stephan
Amyloidosis Registry
Jan 1, 2017
Clinical Studies - Jan 1, 2017 - Dec 31, 2030
Ongoing
Project leader: Hitz Felicitas
Members: Steiner Marianne
HEMATITE
Dec 16, 2016Quality of Life measurement using wrist actigraph in HCV genotype 1 infected, Treatment naive patients suffering from fatique and receiving Viekirax/Exviera.
Clinical Studies - Dec 16, 2016 - Dec 16, 2018
Completed
Project leader: Semela David
Members: Stillhard Roman
ETNA-AF
Dec 6, 2016Nicht-interventionelle Studie zur Edoxaban-Therapie in der klinischen Routinepraxis bei Patienten mit nicht-valvulärem Vorhofflimmern (Non-interventional study on Edoxaban Treatment in routiNe clinical prActise for patients with non valvular Atrial F...
Clinical Studies - Dec 6, 2016 - Dec 15, 2021
Completed
Project leader: Ammann Peter
Members: Gemperle Michaela, Altmann David
Maximise
Dec 5, 2016MAXIMISE (Managing AXIal Manifestations in PsorIatic Arthritis with SEcukinumab), a randomized, double-blind, placebo-controlled, multicenter, 52-week study to assess the efficacy and safety of secukinumab 150 mg or 300 mg s.c. in patients with activ...
Clinical Studies - Dec 5, 2016 - Sep 13, 2019
Completed
Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Hutz Carina Liane, Forrer Silvia
Mongersen GED-0301
Dec 1, 2016A Phase 3, randomized, double-blind, placebo-controlled, multicenter study to investigate the efficacy and safety of mongersen (GED-0301) for the treatment of subjects with active Crohn’s disease.
Clinical Studies - Dec 1, 2016 - Dec 1, 2018
Completed
Members: Dora Barbara, Knellwolf Christina, Krieger-Grübel Claudia, Sulz Michael
PCG-4/UCR
Dec 1, 2016Randomized, double-blind, double-dummy, placebo-controlled, Phase III clinical trial on the efficacy and safety of a 48-weeks treatment with gastroresistant phosphatidylcholine (LT-02) versus placebo versus mesalamine for maintenance of remission in...
Clinical Studies - Dec 1, 2016 - Dec 1, 2018
Completed
Members: Dora Barbara, Knellwolf Christina, Krieger-Grübel Claudia, Sulz Michael
Abbvie M14-234
Dec 1, 2016A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis
Clinical Studies - Dec 1, 2016 - Dec 1, 2018
Automatically Closed
Members: Dora Barbara, Knellwolf Christina, Krieger-Grübel Claudia, Sulz Michael
FIDELIO
Dec 1, 2016Wirksamkeit und Sicherheit von Finerenon bei Patienten mit Typ-2-Diabetes mellitus und der klinischen Diagnose einer diabetischen Nephropathie Eine randomisierte, doppelblinde, placebokontrollierte, multizentrische, Ereignis-gesteuerte Parallelgrupp...
Clinical Studies - Dec 1, 2016 - Aug 31, 2020
Completed
Project leader: Bilz Stefan
Members: Dehos Barbara, Jenni Vera, Räss Andrea
A multicenter, randomized, 52-week, double-blind, parallel group, active controlled study to compare the efficacy and safety of QVM149 with QMF149 in patients with asthma
Nov 11, 2016Asthma is a serious global health problem affecting all age groups. Despite existing therapies, there are significant unmet medical needs in treating asthma. Novartis is developing QVM149, a fixed-dose combination (FDC) of indacaterol acetate, an inh...
Clinical Studies - Nov 11, 2016 - Mar 31, 2018
Automatically Closed
Project leader: Brutsche Martin
Members: Baty Florent, Schlotter Sandra
SAKK 24/14: Anti-EGFR-immunoliposomes loaded with doxorubicin in patients with advanced triple negative EGFR positive breast cancer – A multicenter single arm phase II trial
Nov 7, 2016Advanced triple negative breast cancer (TNBC) is a highly chemosensitive disease displaying a dismal short-term prognosis with more than three quarters of patients in pro-gression 12 months after the initiation of conventional chemotherapy. Approxima...
Clinical Studies - Nov 7, 2016 - May 31, 2023
Automatically Closed
Project leader: Weder Patrik