PD Dr. med. Florian Strasser
scientist (group leader)
Zentrum für Integrative Medizin · Dept. I
The MENAC Trial - A randomised, open-label trial of a multimodal intervention (multimodal = exercise, nutrition and anti-inflammatory medication) versus standard care in cancer patients with cachexia
Aug 24, 2017Cachexia is a common detrimental consequence of cancer limiting therapy, quality of life and survival. There is no standard treatment available and its complex multifactorial pathophysiology requires multimodal treatment. Based on promising phase II...
Clinical Studies - Aug 24, 2017 - May 31, 2020
Automatically Closed
Project leader: Strasser Florian, Domeisen Benedetti Franzisca
Members: Attoun-Knobel Suzanne, Behnke Nadine
QLQ-CAX24 Phase4
Jul 17, 2017The aim of the present study is to test the scale structure, reliability, responsiveness to change and validity of the EORTC QLQ-CAX24 in conjunction with the EORTC QLQ-C30 in people diagnosed with cancer cachexia with different primary cancer diagno...
Clinical Studies - Jul 17, 2017 - Oct 1, 2017
Automatically Closed
Project leader: Strasser Florian
Members: Domeisen Benedetti Franzisca, Attoun-Knobel Suzanne
Monitoring of Patients’ Needs, Professional Triggers and delivered Basic Palliative Care Interventions in Routine inpatient and ambulatory of Advanced Incurable Cancer Patients: A sub-study to pilot the clinical practice tool – ESMO patient guide with KIPCC log
Sep 1, 2016Increasing evidence from randomized studies (Level A) shows that quickly integrated palliative care interventions in the treatment of cancer patients may improve the quality of life of patients and relatives, illness and prognosis understanding and s...
Clinical Studies - Sep 1, 2016 - Mar 31, 2017
Automatically Closed
Project leader: Strasser Florian
Members: Domeisen Benedetti Franzisca
A national palliative care database: A tool to better define the needs of palliative care patients in Switzerland - SwissPALL
Nov 1, 2014
Clinical Studies - Nov 1, 2014 - Jan 1, 2016
Completed
Project leader: Büche Daniel, Strasser Florian
Members: Domeisen Benedetti Franzisca, Forster Michaela
Patient-centred personalised palliative cancer care: A pilot feasibility study of patient-derived clinical benefit-guided chemotherapy in advanced non-small cell lung cancer (NSCLC) patients with a performance status (PS) of 2-3 due to lung cancer (Phönix)
Jun 16, 2014Performance status has shown to be a major negative prognostic factor in lung cancer. Because of the limited time expectancy of these patients, individual clinical benefit (Koeberle) of any intervention should be the main focus. This contrasts the ma...
Clinical Studies - Jun 16, 2014 - Dec 31, 2014
Completed
Project leader: Früh Martin
Members: Strasser Florian, Magayakalbermatten N, Behnke Nadine
Cachexia and Toxicity: cachexia-based dosing vs. standard of care (CAT-Trial)
Jan 23, 2014Cancer cachexia is a frequent condition, characterized by muscle loss not reversible by nutrition only, caused by procatabolic (inflammatory) and hypoanabolic mechanism, with an impact on quality of life, function and survival. An association of musc...
Clinical Studies - Jan 23, 2014 - Nov 30, 2014
Automatically Closed
Project leader: Strasser Florian
Members: Blum David, Jörger Markus, Fornaro Jürgen, Magayakalbermatten N, Behnke Nadine
Swiss-Romanian Cooperation Programme: Overcoming disparities on access to quality basic palliative care in the community: Partnerships to identify and improve clinical, educational, legal and economical barriers
May 1, 2013The project is based on a Swiss-Romanian partnership to develop palliative care in Romania, based on a systematic analysis of the needs, with Swiss experts input in drafting and answering major challenges in offering care to cancer patients. The burd...
Clinical Studies - May 1, 2013 - Apr 30, 2016
Automatically Closed
Project leader: Strasser Florian
Members: Behnke Nadine, Magayakalbermatten N
Decisision criteria guiding chemotherapy in palliative intention: Focusgroup based formal consensus for candidate criteria
Jan 6, 2013Die Wirksamkeit von Krebstherapien für Patienten mit fortgeschrittenenen, unheilbaren Krebserkrankungen wurde in klinischen Studien untersucht, hauptsächlich bezüglich der Beeinflussung des Tumorwachstums des Überlebens, und der Verträglichkeit der T...
Clinical Studies - Jan 6, 2013 - Dec 6, 2016
Automatically Closed
Project leader: Strasser Florian
Members: Magayakalbermatten N
Romanian-Swiss-Cooperation Program: IZERZ0_142226: Integration of medical oncology and palliative care procedures in various institutional and economical settings
Jan 1, 2013Summary of the research plan Background: In the care of advanced incurable cancer patients medical oncologists play a sentinel role in not only providing tumour directed treatment, but also in identifying and treating palliative care needs. In busy o...
Clinical Studies - Jan 1, 2013 - Dec 31, 2015
Completed
Project leader: Strasser Florian
Members: Wilm Simone, Magayakalbermatten N
SMiLE-Lebenssinn, persönliche Werte und Spiritualität bei Patienten mit lebensbedrohlichen Erkrankungen (NFP 67)
Nov 1, 2012Zusammenfassung des Studienprotokolls Principal Investigator : Professor Gian Domenico Borasio, Universitätsspital Lausanne Co-Investigatoren : Mathieu Bernhard, Universitätsspital Lausanne; Dr. Claudia Gamondi Palmesino, Regionalspital Bellinzona...
Clinical Studies - Nov 1, 2012 - Oct 31, 2014
Completed
Project leader: Strasser Florian
Members: Wilm Simone, Magayakalbermatten N
pre-MENAC
Oct 28, 2012
Clinical Studies - Oct 28, 2012 - Sep 26, 2013
Completed
Project leader: Strasser Florian
Members: Wilm Simone, Magayakalbermatten N
Biomarkes Cancer Cachexia in Urin and Blood
Oct 14, 2012Urin
Fundamental Research - Oct 14, 2012 - Dec 15, 2012
Aborted
Project leader: Strasser Florian
Members: Demmer-Steingruber Ruth, Wilm Simone
Decision criteria guiding chemotherapy in palliative intention: prospective study comparing patients, doctors’, and nurses responses- KLS -02785-02-2011
Sep 1, 2012Die Wirksamkeit von Krebstherapien für Patienten mit fortgeschrittenen, unheilbaren Krebserkran-kungen wurde in klinischen Studien untersucht, hauptsächlich bezüglich der Beeinflussung des Tumorwachstums, des Ueberlebens, und der Verträglichkeit der...
Clinical Studies - Sep 1, 2012 - May 31, 2014
Automatically Closed
Project leader: Strasser Florian
Members: Wilm Simone, Magayakalbermatten N
A randomized, double-blind, placebo-controlled multi-center study of BYM338 for treatment of cachexia in patients with stage IV non-small cell lung cancer or stage III/IV adenocarcinoma of the pancreas - EKSG 11/084
Jan 9, 2012Ein ungewollter Gewichtsverlust (Kachexie) ist bei vielen Krebsformen ein unabhängiges Anzeichen für ein kürzeres Gesamtüberleben, selbst vor Beginn einer Chemotherapie. Patienten mit Gewichtsverlust entwickeln zudem häufig stärkere Nebenwirkungen wä...
Clinical Studies - Jan 9, 2012 - Jul 31, 2012
Completed
Project leader: Strasser Florian
Members: Jörger Markus, Gueller Ulrich, Wilm Simone
Living well with INcurable CAncer in Europe: Quality Palliative Cancer Care integrated early in oncology for elderly people - MFZ2011016
Jan 1, 2012Background: The development of palliative care in the last decade demonstrates that so called palliative care interventions are increasingly incorporated in mainstream oncology care among other disciplines. In the curricula of medical oncologists the...
Clinical Studies - Jan 1, 2012 - Dec 31, 2012
Completed
Project leader: Strasser Florian
Development of a module to supplement the EORTC Core instruments for assessment of Health Related Quality of Life in patients with Cancer Cachexia - EKSG 12/091; CTU 12-11
Dec 1, 2011Aims 1. To develop a module to supplement the EORTC QLQ core module, for the assessment of QoL in patients with cancer cachexia. 2. To explore the possible need for parallel development of separate modules for cachexia syndrome, refractory cachexia...
Clinical Studies - Dec 1, 2011 - Dec 31, 2016
Automatically Closed
Project leader: Strasser Florian
Members: Wilm Simone
Systematic Literature Review Population and Outcomes of Clinical Trials in Cachexia
Sep 26, 2011
Clinical Studies - Sep 26, 2011 - Sep 26, 2014
Completed
Project leader: Strasser Florian
Members: Wilm Simone
Europäische Studie über die Symptome von Palliative Care Patienten (EPCCS) – Eine prospektive Datensammlung EKSG 11/072
Sep 1, 2011Patienten mit einer fortgeschrittenen bösartigen Tumorerkrankung entwickeln im Laufe der Erkrankung verschiedenste Beschwerden oder Symptome, die eine wechselnde Stärke zeigen. Schmerzen, Müdigkeit, Übelkeit und Erbrechen, Atemnot, Verstopfung, Appet...
Clinical Studies - Sep 1, 2011 - May 31, 2012
Completed
Project leader: Strasser Florian
First in human clinical development of the MC4 receptor antagonist scFv 1E8a (Obexia) - MFZ 2010_012
Nov 10, 2010For patients with cancer cachexia new mechanism-based pharmacological interventions are required, in addition to a standardized palliative cancer care and basic cachexia management approach. The melanocortin system is one of the important targets for...
Clinical Studies - Nov 10, 2010 - Dec 31, 2011
Aborted
Project leader: Jörger Markus, Strasser Florian
Members: Haile Sarah, Hundsberger Tom
Entwicklung von Dienstleistungsmodellen der integrierten Onkologie und Palliative Care: Untersuchung von temporalen Aspekten, Involvierung von Onkologen, und Chemotherapie-Gebrauch
Nov 10, 2010Introduction: Integrated models of oncological palliative care are demanded (Ferris JCO 2009) and currently develop in various settings. Patient-data centered descriptions of concrete service patterns (SePa) may serve this process. We aim to explore...
Clinical Studies - Nov 10, 2010 - Oct 31, 2011
Completed
Project leader: Strasser Florian
Members: Silzle Tobias, Nestor Karen, Köberle Dieter, Omlin Aurelius, Blum David, Linder Susanne, Früh Martin