Prof. Dr. Burkhard Ludewig
Leiter, Medizinisches Forschungszentrum
Leiter, Institut für Immunbiologie
Klinik-/Instituts-/Zentrumsleiter/in
Medizinisches Forschungszentrum, Institut für Immunbiologie · Dept. Direktion
Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity
Chai Q, Hehlgans T, Stein J, Rülicke T, Thiel V, Luther S, Sparwasser T, Danuser R, Cupovic J, Pérez Shibayama C, Gil Cruz C, Scandella E, Onder L, Ludewig B. Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity 2013; 38:1013-24.
25.04.2013Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity
25.04.2013Immunity 2013; 38:1013-24
Chai Qian, Hehlgans Thomas, Stein Jens V, Rülicke Thomas, Thiel Volker, Luther Sanjiv A, Sparwasser Tim, Danuser Renzo, Cupovic Jovana, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Scandella Elke, Onder Lucas, Ludewig Burkhard
Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions
Coelho F, Figge M, Sharpe J, Ludewig B, Sailer A, Junt T, Zerwes H, Pieczyk M, Scandella E, Danuser R, Mayer J, Swoger J, Hons M, Soriano S, Natale D, Stein J. Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions. Blood 2013; 121:4101-9.
04.04.2013Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions
04.04.2013Blood 2013; 121:4101-9
Coelho Fernanda M, Figge Marc Thilo, Sharpe James, Ludewig Burkhard, Sailer Andreas W, Junt Tobias, Zerwes Hans-Günter, Pieczyk Markus, Scandella Elke, Danuser Renzo, Mayer Jürgen, Swoger Jim, Hons Miroslav, Soriano Silvia F, Natale Daniela, Stein Jens V
A new model for CD8+ T cell memory inflation based upon a recombinant adenoviral vector.
Bolinger B, Sims S, O'Hara G, de Lara C, Tchilian E, Firner S, Engeler D, Ludewig B, Klenerman P. A new model for CD8+ T cell memory inflation based upon a recombinant adenoviral vector. J Immunol 2013; 190:4162-74.
18.03.2013A new model for CD8+ T cell memory inflation based upon a recombinant adenoviral vector.
18.03.2013J Immunol 2013; 190:4162-74
Bolinger Beatrice, Sims Stuart, O'Hara Geraldine, de Lara Catherine, Tchilian Elma, Firner Sonja, Engeler Daniel, Ludewig Burkhard, Klenerman Paul
Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation.
Onder L, Danuser R, Scandella E, Firner S, Chai Q, Hehlgans T, Stein J, Ludewig B. Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation. J Exp Med 2013; 210:465-73.
18.02.2013Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation.
18.02.2013J Exp Med 2013; 210:465-73
Onder Lucas, Danuser Renzo, Scandella Elke, Firner Sonja, Chai Qian, Hehlgans Thomas, Stein Jens V, Ludewig Burkhard
Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice
Frebel H, Ludewig B, Kurrer M, Loffing-Cueni D, Wagner C, Vogel J, Richter K, Braunschweiler T, Schuepbach R, Nindl V, Oxenius A. Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice. J Exp Med 2012; 209:2485-99.
10.12.2012Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice
10.12.2012J Exp Med 2012; 209:2485-99
Frebel Helge, Ludewig Burkhard, Kurrer Michael, Loffing-Cueni Dominique, Wagner Carsten A, Vogel Johannes, Richter Kirsten, Braunschweiler Thomas, Schuepbach Reto A, Nindl Veronika, Oxenius Annette
A global "imaging'' view on systems approaches in immunology
Ludewig B, Stein J, Sharpe J, Cervantes-Barragan L, Thiel V, Bocharov G. A global "imaging'' view on systems approaches in immunology. Eur J Immunol 2012; 42:3116-25.
01.12.2012A global "imaging'' view on systems approaches in immunology
01.12.2012Eur J Immunol 2012; 42:3116-25
Ludewig Burkhard, Stein Jens V, Sharpe James, Cervantes-Barragan Luisa, Thiel Volker, Bocharov Gennady
IL-7-producing stromal cells are critical for lymph node remodeling
Onder L, Coles M, Cupedo T, Westermann J, Kaye P, Richie E, Halin C, Hoorweg K, Iolyeva M, Chai Q, Scandella E, Narang P, Ludewig B. IL-7-producing stromal cells are critical for lymph node remodeling. Blood 2012; 120:4675-83.
06.09.2012IL-7-producing stromal cells are critical for lymph node remodeling
06.09.2012Blood 2012; 120:4675-83
Onder Lucas, Coles Mark, Cupedo Tom, Westermann Jürgen, Kaye Paul, Richie Ellen, Halin Cornelia, Hoorweg Kerim, Iolyeva Maria, Chai Qian, Scandella Elke, Narang Priyanka, Ludewig Burkhard
Tight control - decision-making during T cell-vascular endothelial cell interaction.
Firner S, Onder L, Nindl V, Ludewig B. Tight control - decision-making during T cell-vascular endothelial cell interaction. Front Immunol 2012; 3:279.
27.08.2012Tight control - decision-making during T cell-vascular endothelial cell interaction.
27.08.2012Front Immunol 2012; 3:279
Firner Sonja, Onder Lucas, Nindl Veronika, Ludewig Burkhard
Cooperation of Th1 and Th17 cells determines transition from autoimmune myocarditis to dilated cardiomyopathy
Nindl V, Rülicke T, Rudin M, Kopf M, Di Padova F, Scandella E, Thiel V, Züst R, De Giuli R, Ratering D, Maier R, Ludewig B. Cooperation of Th1 and Th17 cells determines transition from autoimmune myocarditis to dilated cardiomyopathy. Eur J Immunol 2012; 42:2311-21.
13.07.2012Cooperation of Th1 and Th17 cells determines transition from autoimmune myocarditis to dilated cardiomyopathy
13.07.2012Eur J Immunol 2012; 42:2311-21
Nindl Veronika, Rülicke Thomas, Rudin Markus, Kopf Manfred, Di Padova Franco, Scandella Elke, Thiel Volker, Züst Roland, De Giuli Rita, Ratering David, Maier Reinhard, Ludewig Burkhard
Identification of protective B cell antigens of Legionella pneumophila
Weber S, Hilbi H, Ludewig B, Rösli C, Scandella E, Tchang V, Spörri R, Küntzel A, Joller N, Oxenius A. Identification of protective B cell antigens of Legionella pneumophila. J Immunol 2012; 189:841-9.
13.06.2012Identification of protective B cell antigens of Legionella pneumophila
13.06.2012J Immunol 2012; 189:841-9
Weber Stefan S, Hilbi Hubert, Ludewig Burkhard, Rösli Christoph, Scandella Elke, Tchang Vincent S, Spörri Roman, Küntzel Anna Barbara, Joller Nicole, Oxenius Annette
Regulatory T cells selectively preserve immune privilege of self-antigens during viral central nervous system infection.
Cervantes-Barragan L, Firner S, Bechmann I, Waisman A, Lahl K, Sparwasser T, Thiel V, Ludewig B. Regulatory T cells selectively preserve immune privilege of self-antigens during viral central nervous system infection. J Immunol 2012; 188:3678-85.
09.03.2012Regulatory T cells selectively preserve immune privilege of self-antigens during viral central nervous system infection.
09.03.2012J Immunol 2012; 188:3678-85
Cervantes-Barragan Luisa, Firner Sonja, Bechmann Ingo, Waisman Ari, Lahl Katharina, Sparwasser Tim, Thiel Volker, Ludewig Burkhard
Ciprofloxacin and epirubicin synergistically induce apoptosis in human urothelial cancer cell lines
Engeler D, Scandella E, Ludewig B, Schmid H. Ciprofloxacin and epirubicin synergistically induce apoptosis in human urothelial cancer cell lines. Urol Int 2012; 88:343-9.
01.03.2012Ciprofloxacin and epirubicin synergistically induce apoptosis in human urothelial cancer cell lines
01.03.2012Urol Int 2012; 88:343-9
Engeler Daniel, Scandella Elke, Ludewig Burkhard, Schmid Hans-Peter
Plasmacytoid dendritic cells control T-cell response to chronic viral infection.
Cervantes-Barragan L, Lewis K, Firner S, Thiel V, Hugues S, Reith W, Ludewig B, Reizis B. Plasmacytoid dendritic cells control T-cell response to chronic viral infection. Proc Natl Acad Sci U S A 2012; 109:3012-7.
06.02.2012Plasmacytoid dendritic cells control T-cell response to chronic viral infection.
06.02.2012Proc Natl Acad Sci U S A 2012; 109:3012-7
Cervantes-Barragan Luisa, Lewis Kanako L, Firner Sonja, Thiel Volker, Hugues Stephanie, Reith Walter, Ludewig Burkhard, Reizis Boris
T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease.
Gil-Cruz C, Perez-Shibayama C, Firner S, Waisman A, Bechmann I, Thiel V, Cervantes-Barragan L, Ludewig B. T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease. Proc Natl Acad Sci U S A 2012; 109:1233-8.
09.01.2012T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease.
09.01.2012Proc Natl Acad Sci U S A 2012; 109:1233-8
Gil-Cruz Cristina, Perez-Shibayama Christian, Firner Sonja, Waisman Ari, Bechmann Ingo, Thiel Volker, Cervantes-Barragan Luisa, Ludewig Burkhard
CD169(+) macrophages take the bullet
Ludewig B, Cervantes-Barragan L. CD169(+) macrophages take the bullet. Nat Immunol 2011; 13:13-4.
16.12.2011CD169(+) macrophages take the bullet
16.12.2011Nat Immunol 2011; 13:13-4
Ludewig Burkhard, Cervantes-Barragan Luisa
A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo.
Onder L, Scandella E, Chai Q, Firner S, Mayer C, Sparwasser T, Thiel V, Rülicke T, Ludewig B. A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo. Front Immunol 2011; 2:50.
12.10.2011A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo.
12.10.2011Front Immunol 2011; 2:50
Onder Lucas, Scandella Elke, Chai Qian, Firner Sonja, Mayer Christian T, Sparwasser Tim, Thiel Volker, Rülicke Thomas, Ludewig Burkhard
Simulation of the interferon-mediated protective field in lymphoid organs with their spatial and functional organization taken into consideration
Bocharov G, Danilov A, Vassilevski Y, Marchuk G, Chereshnev V, Ludewig B. Simulation of the interferon-mediated protective field in lymphoid organs with their spatial and functional organization taken into consideration. Dokl Biol Sci 2011; 439:194-6.
28.09.2011Simulation of the interferon-mediated protective field in lymphoid organs with their spatial and functional organization taken into consideration
28.09.2011Dokl Biol Sci 2011; 439:194-6
Bocharov G A, Danilov A A, Vassilevski Yu V, Marchuk G I, Chereshnev V A, Ludewig Burkhard
Subversion of innate and adaptive immune activation induced by structurally modified lipopolysaccharide from Salmonella typhimurium
Pastelin-Palacios R, Isibasi A, Gunn J, Bonifaz L, Alpuche-Aranda C, Becker I, García-Zepeda E, Cunningham A, Ludewig B, Arriaga-Pizano L, Cervantes-Barragan L, Moreno-Eutimio M, Pérez Shibayama C, Gil Cruz C, López-Macías C. Subversion of innate and adaptive immune activation induced by structurally modified lipopolysaccharide from Salmonella typhimurium. Immunology 2011; 133:469-81.
02.06.2011Subversion of innate and adaptive immune activation induced by structurally modified lipopolysaccharide from Salmonella typhimurium
02.06.2011Immunology 2011; 133:469-81
Pastelin-Palacios Rodolfo, Isibasi Armando, Gunn John S, Bonifaz Laura, Alpuche-Aranda Celia, Becker Ingeborg, García-Zepeda Eduardo A, Cunningham Adam F, Ludewig Burkhard, Arriaga-Pizano Lourdes, Cervantes-Barragan Luisa, Moreno-Eutimio Mario A, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, López-Macías Constantino
Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
Züst R, Ludewig B, Siddell S, Diamond M, Barchet W, Baker S, Szretter K, Ziebuhr J, Neuman B, Maier R, Habjan M, Cervantes-Barragan L, Thiel V. Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nat Immunol 2011; 12:137-43.
09.01.2011Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
09.01.2011Nat Immunol 2011; 12:137-43
Züst Roland, Ludewig Burkhard, Siddell Stuart G, Diamond Michael S, Barchet Winfried, Baker Susan C, Szretter Kristy J, Ziebuhr John, Neuman Benjamin W, Maier Reinhard, Habjan Matthias, Cervantes-Barragan Luisa, Thiel Volker
Dendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity
Cervantes-Barragan L, Ludewig B, Rohrlich P, Romero P, Speiser D, Levy F, Janda J, Sierro S, Maier R, Züst R, Thiel V. Dendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity. MBio 2010; 1
14.09.2010Dendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity
14.09.2010MBio 2010; 1
Cervantes-Barragan Luisa, Ludewig Burkhard, Rohrlich Pierre-Simon, Romero Pedro, Speiser Daniel, Levy Frederic, Janda Jozef, Sierro Sophie, Maier Reinhard, Züst Roland, Thiel Volker