Dr. med. et phil. nat. David Semela
Leitender Arzt Hepatologie
Forschungsgruppenleiter Liver Biology Lab, Departement Biomedizin, Universitätsspital Basel
Leitende(r) Arzt/Ärztin
Gastroenterologie | Hepatologie · Dept. I
Sorafenib: from literature to clinical practice
Di Marco V, De Vita F, Koskinas J, Semela D, Toniutto P, Verslype C. Sorafenib: from literature to clinical practice. Ann Oncol 2013; 24 Suppl 2:ii30-7.
01.04.2013Sorafenib: from literature to clinical practice
01.04.2013Ann Oncol 2013; 24 Suppl 2:ii30-7
Di Marco V, De Vita F, Koskinas J, Semela David, Toniutto P, Verslype C
Constitutive Notch2 signaling induces hepatic tumors in mice
Dill M, Tornillo L, Fritzius T, Terracciano L, Semela D, Bettler B, Heim M, Tchorz J. Constitutive Notch2 signaling induces hepatic tumors in mice. Hepatology 2013; 57:1607-19.
14.03.2013Constitutive Notch2 signaling induces hepatic tumors in mice
14.03.2013Hepatology 2013; 57:1607-19
Dill Michael T, Tornillo Luigi, Fritzius Thorsten, Terracciano Luigi, Semela David, Bettler Bernhard, Heim Markus H, Tchorz Jan S
TIE2-expressing monocytes: a novel cellular biomarker for hepatocellular carcinoma?
De Palma M, Coukos G, Semela D. TIE2-expressing monocytes: a novel cellular biomarker for hepatocellular carcinoma?. Hepatology 2013; 57:1294-6.
06.03.2013TIE2-expressing monocytes: a novel cellular biomarker for hepatocellular carcinoma?
06.03.2013Hepatology 2013; 57:1294-6
De Palma Michele, Coukos George, Semela David
Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection
Rau M, Geier A, Mullhaupt B, Semela D, Moradpour D, Dufour J, Dill M, Schmitt J, Weisskopf M, Becker P, Manser C, Russmann S, Stickel F, Swiss Hepatitis C Cohort Study Group (SCCS). Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection. J Hepatol 2012; 58:669-75.
27.11.2012Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection
27.11.2012J Hepatol 2012; 58:669-75
Rau Monika, Geier Andreas, Mullhaupt Beat, Semela David, Moradpour Darius, Dufour Jean-François, Dill Michael T, Schmitt Johannes, Weisskopf Michael, Becker Philip P, Manser Christine N, Russmann Stefan, Stickel Felix, Swiss Hepatitis C Cohort Study Group (SCCS)
Leberversagen bei einer 27-jährigen Patientin
Gertsch T, Pfammatter T, Braun M, Hechelhammer L, Meyenberger C, Semela D, Sawatzki M. Leberversagen bei einer 27-jährigen Patientin - Liver Failure in a 27 Years old Female Patient. Praxis 2012; 16:1051-1055.
08.08.2012Leberversagen bei einer 27-jährigen Patientin
08.08.2012Praxis 2012; 16:1051-1055
Gertsch Tobias, Pfammatter Thomas, Braun Monika, Hechelhammer Lukas, Meyenberger Christa, Semela David, Sawatzki Mikael
[Liver failure in a 27 years old female patient]
Gertsch T, Pfammatter T, Braun M, Hechelhammer L, Meyenberger C, Semela D, Sawatzki M. [Liver failure in a 27 years old female patient]. Praxis (Bern 1994) 2012; 101:1051-5.
08.08.2012[Liver failure in a 27 years old female patient]
08.08.2012Praxis (Bern 1994) 2012; 101:1051-5
Gertsch T, Pfammatter T, Braun M, Hechelhammer Lukas, Meyenberger C, Semela David, Sawatzki M
Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma
Kuske L, Dufour J, Cerny A, Malinverni R, Heim M, Malé P, Moradpour D, Semela D, Negro F, Mullhaupt B, Mensen A, Swiss Hepatitis C Cohort Study. Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma. Swiss Med Wkly 2012; 142:w13651.
06.08.2012Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma
06.08.2012Swiss Med Wkly 2012; 142:w13651
Kuske Lorenz, Dufour Jean-François, Cerny Andreas, Malinverni Raffaele, Heim Markus H, Malé Pierre Jean, Moradpour Darius, Semela David, Negro Francesco, Mullhaupt Beat, Mensen Armand, Swiss Hepatitis C Cohort Study
Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection
Patin E, Stewart G, Booth D, George J, Casanova J, Bréchot C, Rice C, Talal A, Jacobson I, Bourlière M, Theodorou I, Poynard T, Negro F, Pol S, Bochud P, Abel L, Swiss Hepatitis C Cohort Study Group, International Hepatitis C Genetics Consortium, Suppiah V, Martinetti G, Hirsch H, Kutalik Z, Guergnon J, Bibert S, Nalpas B, Jouanguy E, Munteanu M, Bousquet L, Argiro L, Halfon P, Boland A, Mullhaupt B, Semela D, Dufour J, Heim M, Moradpour D, Cerny A, Malinverni R, French ANRS HC EP 26 Genoscan Study Group. Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. Gastroenterology 2012; 143:1244-52.e1-12.
27.07.2012Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection
27.07.2012Gastroenterology 2012; 143:1244-52.e1-12
Patin Etienne, Stewart Graeme, Booth David R, George Jacob, Casanova Jean-Laurent, Bréchot Christian, Rice Charles M, Talal Andrew H, Jacobson Ira M, Bourlière Marc, Theodorou Ioannis, Poynard Thierry, Negro Francesco, Pol Stanislas, Bochud Pierre-Yves, Abel Laurent, Swiss Hepatitis C Cohort Study Group, International Hepatitis C Genetics Consortium, Suppiah Vijayaprakash, Martinetti Gladys, Hirsch Hans, Kutalik Zoltán, Guergnon Julien, Bibert Stéphanie, Nalpas Bertrand, Jouanguy Emmanuelle, Munteanu Mona, Bousquet Laurence, Argiro Laurent, Halfon Philippe, Boland Anne, Mullhaupt Beat, Semela David, Dufour Jean-François, Heim Markus H, Moradpour Darius, Cerny Andreas, Malinverni Raffaele, French ANRS HC EP 26 Genoscan Study Group
Epidemiologie und Ätiologie des hepatozellulären Karzinoms
Sawatzki M, Semela D. Epidemiologie und Ätiologie des hepatozellulären Karzinoms. Tumordiagnostik und Therapie 2012; 1:10-13.
17.02.2012Epidemiologie und Ätiologie des hepatozellulären Karzinoms
17.02.2012Tumordiagnostik und Therapie 2012; 1:10-13
Sawatzki Mikael, Semela David
Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice
Dill M, Heim M, Radtke F, Meili-Butz S, Terracciano L, Tornillo L, Hlushchuk R, Djonov V, Rothweiler S, Semela D. Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice. Gastroenterology 2012; 142:967-977.e2.
12.01.2012Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice
12.01.2012Gastroenterology 2012; 142:967-977.e2
Dill Michael T, Heim Markus H, Radtke Freddy, Meili-Butz Silvia, Terracciano Luigi, Tornillo Luigi, Hlushchuk Ruslan, Djonov Valentin, Rothweiler Sonja, Semela David
[Hepatocellular carcinoma]
Semela D, Heim M. [Hepatocellular carcinoma]. Ther Umsch 2011; 68:213-7.
01.04.2011[Hepatocellular carcinoma]
01.04.2011Ther Umsch 2011; 68:213-7
Semela David, Heim Markus
[44 year old gardener with lower back pain, myalgia and fever]
Bareiss D, Semela D, Heim M, Terracciano L, Hunziker S. [44 year old gardener with lower back pain, myalgia and fever]. Praxis (Bern 1994) 2010; 99:127-32.
20.01.2010[44 year old gardener with lower back pain, myalgia and fever]
20.01.2010Praxis (Bern 1994) 2010; 99:127-32
Bareiss D, Semela David, Heim M, Terracciano L, Hunziker S
Angiogenesis in liver disease
Fernández M, Semela D, Bruix J, Colle I, Pinzani M, Bosch J. Angiogenesis in liver disease. J Hepatol 2008; 50:604-20.
31.12.2008Angiogenesis in liver disease
31.12.2008J Hepatol 2008; 50:604-20
Fernández Mercedes, Semela David, Bruix Jordi, Colle Isabelle, Pinzani Massimo, Bosch Jaume
Nitric oxide promotes caspase-independent hepatic stellate cell apoptosis through the generation of reactive oxygen species
Langer D, Das A, Semela D, Kang-Decker N, Hendrickson H, Bronk S, Katusic Z, Gores G, Shah V. Nitric oxide promotes caspase-independent hepatic stellate cell apoptosis through the generation of reactive oxygen species. Hepatology 2008; 47:1983-93.
01.06.2008Nitric oxide promotes caspase-independent hepatic stellate cell apoptosis through the generation of reactive oxygen species
01.06.2008Hepatology 2008; 47:1983-93
Langer Daniel A, Das Amitava, Semela David, Kang-Decker Ningling, Hendrickson Helen, Bronk Steven F, Katusic Zvonimir S, Gores Gregory J, Shah Vijay H
Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma
Piguet A, Semela D, Keogh A, Wilkens L, Stroka D, Stoupis C, St-Pierre M, Dufour J. Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma. J Hepatol 2008; 49:78-87.
28.04.2008Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma
28.04.2008J Hepatol 2008; 49:78-87
Piguet Anne-Christine, Semela David, Keogh Adrian, Wilkens Ludwig, Stroka Deborah, Stoupis Christoforos, St-Pierre Marie V, Dufour Jean-François
Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function
Semela D, Das A, Langer D, Kang N, Leof E, Shah V. Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function. Gastroenterology 2008; 135:671-9.
16.04.2008Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function
16.04.2008Gastroenterology 2008; 135:671-9
Semela David, Das Amitava, Langer Daniel, Kang Ningling, Leof Edward, Shah Vijay
Expression and activity of the cytochrome P450 2E1 in patients with nonalcoholic steatosis and steatohepatitis
Chtioui H, Semela D, Ledermann M, Zimmermann A, Dufour J. Expression and activity of the cytochrome P450 2E1 in patients with nonalcoholic steatosis and steatohepatitis. Liver Int 2007; 27:764-71.
01.08.2007Expression and activity of the cytochrome P450 2E1 in patients with nonalcoholic steatosis and steatohepatitis
01.08.2007Liver Int 2007; 27:764-71
Chtioui Haithem, Semela David, Ledermann Monika, Zimmermann Arthur, Dufour Jean-François
Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte?
Lee J, Semela D, Iredale J, Shah V. Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte?. Hepatology 2007; 45:817-25.
01.03.2007Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte?
01.03.2007Hepatology 2007; 45:817-25
Lee June Sung, Semela David, Iredale John, Shah Vijay H
Nitric oxide promotes endothelial cell survival signaling through S-nitrosylation and activation of dynamin-2
Kang-Decker N, Cao S, Chatterjee S, Yao J, Egan L, Semela D, Mukhopadhyay D, Shah V. Nitric oxide promotes endothelial cell survival signaling through S-nitrosylation and activation of dynamin-2. J Cell Sci 2007; 120:492-501.
01.02.2007Nitric oxide promotes endothelial cell survival signaling through S-nitrosylation and activation of dynamin-2
01.02.2007J Cell Sci 2007; 120:492-501
Kang-Decker Ningling, Cao Sheng, Chatterjee Suvro, Yao Janet, Egan Laurence J, Semela David, Mukhopadhyay Debabrata, Shah Vijay
Vascular remodeling and antitumoral effects of mTOR inhibition in a rat model of hepatocellular carcinoma
Semela D, Piguet A, Kolev M, Schmitter K, Hlushchuk R, Djonov V, Stoupis C, Dufour J. Vascular remodeling and antitumoral effects of mTOR inhibition in a rat model of hepatocellular carcinoma. J Hepatol 2007; 46:840-8.
17.01.2007Vascular remodeling and antitumoral effects of mTOR inhibition in a rat model of hepatocellular carcinoma
17.01.2007J Hepatol 2007; 46:840-8
Semela David, Piguet Anne-Christine, Kolev Mirjam, Schmitter Karin, Hlushchuk Ruslan, Djonov Valentin, Stoupis Christoforos, Dufour Jean-François