Prof. Dr. Christoph Driessen
Chefarzt Klinik für Medizinische Onkologie und Hämatologie, Kantonsspital St.Gallen
Stellvertretender Leiter Comprehensive Cancer Center Kantonsspital St.Gallen
Medizinische Onkologie und Hämatologie · Dept. I
Complete hematological and major molecular response through treatment with low-dose Interferon alpha 2a in high-risk polycythemia vera patient: a case report
Driessen C, Noppen C, Boonen G, Drewe J. Complete hematological and major molecular response through treatment with low-dose Interferon alpha 2a in high-risk polycythemia vera patient: a case report. Clin Case Rep 2021; 9:e04903.
06.10.2021Complete hematological and major molecular response through treatment with low-dose Interferon alpha 2a in high-risk polycythemia vera patient: a case report
06.10.2021Clin Case Rep 2021; 9:e04903
Driessen Christoph, Noppen Christoph, Boonen Georg, Drewe Juergen
Consolidation and Maintenance in Newly Diagnosed Multiple Myeloma
Sonneveld P, Driessen C, Pour L, Levin M, Bos G, Ypma P, Wu K, van de Velden V, Oliva S, Broijl A, Croockewit A, Boccadoro M, Spencer A, Palumbo G, Offidani M, van de Donk N, Hveding C, Waage A, Minnema M, Troia R, Cornelisse P, Zamagni E, Zander T, Zweegman S, Ludwig H, Aquino S, van der Holt B, Beksac M, Dimopoulos M, Wester R, Hájek R, Gulbrandsen N, Gregersen H, Morelli A, De Rosa L, Cafro A, Gay F, Dozza L, Pantani L, Cavo M. Consolidation and Maintenance in Newly Diagnosed Multiple Myeloma. J Clin Oncol 2021; 39:3613-3622.
14.09.2021Consolidation and Maintenance in Newly Diagnosed Multiple Myeloma
14.09.2021J Clin Oncol 2021; 39:3613-3622
Sonneveld Pieter, Driessen Christoph, Pour Luca, Levin Mark-David, Bos Gerard, Ypma Paula F, Wu KaLung, van de Velden Vincent, Oliva Stefania, Broijl Annemiek, Croockewit Alexandra, Boccadoro Mario, Spencer Andrew, Palumbo Giuseppe A, Offidani Massimo, van de Donk Niels W C J, Hveding Cecilie, Waage Anders, Minnema Monique C, Troia Rosella, Cornelisse Petra, Zamagni Elena, Zander Thilo, Zweegman Sonja, Ludwig Heinz, Aquino Sara, van der Holt Bronno, Beksac Meral, Dimopoulos Meletios A, Wester Ruth, Hájek Roman, Gulbrandsen Nina, Gregersen Henrik, Morelli Annamaria, De Rosa Luca, Cafro AnneMaria, Gay Francesca, Dozza Luca, Pantani Lucia, Cavo Michele
Treatment with HIV-Protease Inhibitor Nelfinavir Identifies Membrane Lipid Composition and Fluidity as a Therapeutic Target in Advanced Multiple Myeloma
Besse L, Pilon M, Farhan H, Vulpe C, Overkleeft H, Driessen C, Ståhlman M, Huber J, Bolomsky A, Ludwig H, Hannich J, Loguinov A, Everts B, Berkers C, Besse A, Borén J, Florea B, Sathianathan M, Stolze S, Sobh A, Zaal E, van der Ham A, Ruiz M, Phuyal S, Büchler L. Treatment with HIV-Protease Inhibitor Nelfinavir Identifies Membrane Lipid Composition and Fluidity as a Therapeutic Target in Advanced Multiple Myeloma. Cancer Res 2021; 81:4581-4593.
22.06.2021Treatment with HIV-Protease Inhibitor Nelfinavir Identifies Membrane Lipid Composition and Fluidity as a Therapeutic Target in Advanced Multiple Myeloma
22.06.2021Cancer Res 2021; 81:4581-4593
Besse Lenka, Pilon Marc, Farhan Hesso, Vulpe Christopher D, Overkleeft Herman S, Driessen Christoph, Ståhlman Marcus, Huber Julia, Bolomsky Arnold, Ludwig Heinz, Hannich J Thomas, Loguinov Alex, Everts Bart, Berkers Celia R, Besse Andrej, Borén Jan, Florea Bogdan I, Sathianathan Marc, Stolze Sara C, Sobh Amin, Zaal Esther A, van der Ham Alwin J, Ruiz Mario, Phuyal Santosh, Büchler Lorina
Novel Peptide-drug Conjugate Melflufen Efficiently Eradicates Bortezomib-resistant Multiple Myeloma Cells Including Tumor-initiating Myeloma Progenitor Cells
Byrgazov K, Besse A, Kraus M, Slipicevic A, Lehmann F, Driessen C, Besse L. Novel Peptide-drug Conjugate Melflufen Efficiently Eradicates Bortezomib-resistant Multiple Myeloma Cells Including Tumor-initiating Myeloma Progenitor Cells. Hemasphere 2021; 5:e602.
12.06.2021Novel Peptide-drug Conjugate Melflufen Efficiently Eradicates Bortezomib-resistant Multiple Myeloma Cells Including Tumor-initiating Myeloma Progenitor Cells
12.06.2021Hemasphere 2021; 5:e602
Byrgazov Konstantin, Besse Andrej, Kraus Marianne, Slipicevic Ana, Lehmann Fredrik, Driessen Christoph, Besse Lenka
Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group
Richardson P, Goldschmidt H, Harousseau J, Dytfeld D, Mellqvist U, Chng W, Hou J, Bergsagel P, Riva E, Leleu X, Bladé J, Driessen C, Quach H, Ocio E, Vesole D, Waage A, Laubach J, Munshi N, Gay F, Dimopoulos M, Rajkumar S, Mateos M, Cook G, Nahi H, Harrison S, Sezer O, Holstein S, Zweegman S, Usmani S, Boccadoro M, Hari P, Kaiser M, Costa L, Beksac M, Maiolino A, Leal da Costa F, Sidana S, Jurczyszyn A, Facon T, Durie B, Yong K, Martin T, Schjesvold F, Terpos E, Mikhael J, Ludwig H, Bahlis N, Zamagni E, Davies F, San Miguel J, Kumar S, Raje N, van de Donk N, Lonial S, Berdeja J, Hungria V, Baz R, Weisel K, Vangsted A, Fonseca R, Engelhardt M, Sonneveld P, Einsele H, João C, Anderson K, Hájek R, Lentzsch S, Kristinsson S, Cavo M, Moreau P. Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group. Lancet Oncol 2021; 22:e105-e118.
01.01.2021Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group
01.01.2021Lancet Oncol 2021; 22:e105-e118
Richardson Paul G, Goldschmidt Hartmut, Harousseau Jean-Luc, Dytfeld Dominik, Mellqvist Ulf-Henrik, Chng Wee Joo, Hou Jian, Bergsagel Peter Leif, Riva Eloisa, Leleu Xavier, Bladé Joan, Driessen Christoph, Quach Hang, Ocio Enrique M, Vesole David H, Waage Anders, Laubach Jacob, Munshi Nikhil C, Gay Francesca, Dimopoulos Meletios A, Rajkumar S Vincent, Mateos Maria-Victoria, Cook Gordon, Nahi Hareth, Harrison Simon, Sezer Orhan, Holstein Sarah, Zweegman Sonja, Usmani Saad Z, Boccadoro Mario, Hari Parameswaran, Kaiser Martin, Costa Luciano J, Beksac Meral, Maiolino Angelo, Leal da Costa Fernando, Sidana Surbhi, Jurczyszyn Artur, Facon Thierry, Durie Brian G M, Yong Kwee, Martin Thomas, Schjesvold Fredrik, Terpos Evangelos, Mikhael Joseph, Ludwig Heinz, Bahlis Nizar, Zamagni Elena, Davies Faith, San Miguel Jesús, Kumar Shaji K, Raje Noopur, van de Donk Niels, Lonial Sagar, Berdeja Jesus G, Hungria Vania, Baz Rachid, Weisel Katja, Vangsted Annette, Fonseca Rafael, Engelhardt Monika, Sonneveld Pieter, Einsele Hermann, João Cristina, Anderson Kenneth C, Hájek Roman, Lentzsch Suzanne, Kristinsson Sigurdur Y, Cavo Michele, Moreau Philippe
Up-regulation of multidrug resistance protein MDR1/ABCB1 in carfilzomib-resistant multiple myeloma differentially affects efficacy of anti-myeloma drugs
Byrgazov K, Kraus M, Besse A, Slipicevic A, Lehmann F, Driessen C, Besse L. Up-regulation of multidrug resistance protein MDR1/ABCB1 in carfilzomib-resistant multiple myeloma differentially affects efficacy of anti-myeloma drugs. Leuk Res 2020; 101:106499.
31.12.2020Up-regulation of multidrug resistance protein MDR1/ABCB1 in carfilzomib-resistant multiple myeloma differentially affects efficacy of anti-myeloma drugs
31.12.2020Leuk Res 2020; 101:106499
Byrgazov Konstantin, Kraus Marianne, Besse Andrej, Slipicevic Ana, Lehmann Fredrik, Driessen Christoph, Besse Lenka
Recommendations for vaccination in multiple myeloma: a consensus of the European Myeloma Network
Ludwig H, Einsele H, Delforge M, Caers J, Weisel K, Jackson G, Garderet L, Engelhardt M, van de Donk N, Leleu X, Goldschmidt H, Beksac M, Nijhof I, Abildgaard N, Bringhen S, Mateos M, Mohty M, Boccadoro M, Moreau P, San-Miguel J, Cavo M, Pawlyn C, Zweegman S, Facon T, Driessen C, Hájek R, Dimopoulos M, Gay F, Avet-Loiseau H, Terpos E, Zojer N, Sonneveld P. Recommendations for vaccination in multiple myeloma: a consensus of the European Myeloma Network. Leukemia 2020; 35:31-44.
19.08.2020Recommendations for vaccination in multiple myeloma: a consensus of the European Myeloma Network
19.08.2020Leukemia 2020; 35:31-44
Ludwig Heinz, Einsele Hermann, Delforge Michel, Caers Jo, Weisel Katja, Jackson Graham, Garderet Laurent, Engelhardt Monika, van de Donk Niels, Leleu Xavier, Goldschmidt Hartmut, Beksac Meral, Nijhof Inger, Abildgaard Niels, Bringhen Sara, Mateos Maria-Victoria, Mohty Mohamad, Boccadoro Mario, Moreau Philippe, San-Miguel Jesus, Cavo Michele, Pawlyn Charlotte, Zweegman Sonja, Facon Thierry, Driessen Christoph, Hájek Roman, Dimopoulos Melitios A, Gay Francesca, Avet-Loiseau Hervé, Terpos Evangelos, Zojer Niklas, Sonneveld Pieter
Autologous haematopoietic stem-cell transplantation versus bortezomib-melphalan-prednisone, with or without bortezomib-lenalidomide-dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study
Sonneveld P, von dem Borne P, Durian M, Hájek R, Boersma R, Wu K, Morelli A, Aquino S, Ludwig H, Bos G, Levin M, Benevolo G, Pascarella A, Troia R, Caravita di Toritto T, Zander T, Boccadoro M, Spencer A, Carvalho S, Palmas A, Cafro A, Mandigers C, Minnema M, van Marwijk Kooy M, Mellqvist U, Gimsing P, Waage A, Specchia G, Driessen C, Broijl A, Andersen N, Patriarca F, Palumbo G, Zamagni E, van der Velden V, Oliva S, Zweegman S, van der Holt B, Dozza L, Dimopoulos M, Petrucci M, Pantani L, Beksac M, Gay F, Montefusco V, Galli M, Liberati A, Zambello R, Vincelli I, Offidani M, Ballanti S, Croockewit A, Grasso M, Ypma P, Pour L, Belotti A, Hansson M, Gamberi B, Maisnar V, Cavo M. Autologous haematopoietic stem-cell transplantation versus bortezomib-melphalan-prednisone, with or without bortezomib-lenalidomide-dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study. Lancet Haematol 2020; 7:e456-e468.
30.04.2020Autologous haematopoietic stem-cell transplantation versus bortezomib-melphalan-prednisone, with or without bortezomib-lenalidomide-dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study
30.04.2020Lancet Haematol 2020; 7:e456-e468
Sonneveld Pieter, von dem Borne Peter A, Durian Marc, Hájek Roman, Boersma Rinske, Wu Ka Lung, Morelli Anna Maria, Aquino Sara, Ludwig Heinz, Bos Gerard, Levin Mark-David, Benevolo Giulia, Pascarella Anna, Troia Rossella, Caravita di Toritto Tommaso, Zander Thilo, Boccadoro Mario, Spencer Andrew, Carvalho Susanna, Palmas Angelo, Cafro Anna Maria, Mandigers Caroline, Minnema Monique, van Marwijk Kooy Marinus, Mellqvist Ulf-Henrik, Gimsing Peter, Waage Anders, Specchia Giorgina, Driessen Christoph, Broijl Annemiek, Andersen Niels Frost, Patriarca Francesca, Palumbo Giuseppe A, Zamagni Elena, van der Velden Vincent H J, Oliva Stefania, Zweegman Sonja, van der Holt Bronno, Dozza Luca, Dimopoulos Meletios A, Petrucci Maria Teresa, Pantani Lucia, Beksac Meral, Gay Francesca, Montefusco Vittorio, Galli Monica, Liberati Anna Marina, Zambello Renato, Vincelli Iolanda D, Offidani Massimo, Ballanti Stelvio, Croockewit Alexsandra, Grasso Mariella, Ypma Paula, Pour Ludek, Belotti Angelo, Hansson Markus, Gamberi Barbara, Maisnar Vladimir, Cavo Michele
Impaired proteolysis by SPPL2a causes CD74 fragment accumulation that can be recognized by anti-CD74 autoantibodies in human ankylosing spondylitis
van Kempen T, Radstake T, Witte T, Baerlecken N, Lebbink R, Driessen C, Nordkamp M, Lindenbergh M, Leijten E, Boes M. Impaired proteolysis by SPPL2a causes CD74 fragment accumulation that can be recognized by anti-CD74 autoantibodies in human ankylosing spondylitis. Eur J Immunol 2020; 50:1209-1219.
14.04.2020Impaired proteolysis by SPPL2a causes CD74 fragment accumulation that can be recognized by anti-CD74 autoantibodies in human ankylosing spondylitis
14.04.2020Eur J Immunol 2020; 50:1209-1219
van Kempen Tessa S, Radstake Timothy R D J, Witte Torsten, Baerlecken Niklas, Lebbink Robert-Jan, Driessen Christoph, Nordkamp Michel Olde, Lindenbergh Marthe F S, Leijten Emmerik F A, Boes Marianne
Predictive impact of antibiotics in patients with advanced non small-cell lung cancer receiving immune checkpoint inhibitors : Antibiotics immune checkpoint inhibitors in advanced NSCLC
Schett A, Rothschild S, Curioni-Fontecedro A, Krähenbühl S, Früh M, Schmid S, Driessen C, Jörger M. Predictive impact of antibiotics in patients with advanced non small-cell lung cancer receiving immune checkpoint inhibitors : Antibiotics immune checkpoint inhibitors in advanced NSCLC. Cancer Chemother Pharmacol 2019; 85:121-131.
19.11.2019Predictive impact of antibiotics in patients with advanced non small-cell lung cancer receiving immune checkpoint inhibitors : Antibiotics immune checkpoint inhibitors in advanced NSCLC
19.11.2019Cancer Chemother Pharmacol 2019; 85:121-131
Schett Anne, Rothschild Sacha I, Curioni-Fontecedro Alessandra, Krähenbühl Stephan, Früh Martin, Schmid S, Driessen Christoph, Jörger Markus
Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma
Lin Y, Greene C, Boise L, Driessen C, Ferguson I, Marcoulis M, Mariano M, Barwick B, Way G, Wiita A. Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma. Blood Adv 2019; 3:3214-3227.
12.11.2019Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma
12.11.2019Blood Adv 2019; 3:3214-3227
Lin Yu-Hsiu T, Greene Casey S, Boise Lawrence H, Driessen Christoph, Ferguson Ian D, Marcoulis Makeba, Mariano Margarette C, Barwick Benjamin G, Way Gregory P, Wiita Arun P
Nelfinavir and lenalidomide/dexamethasone in patients with lenalidomide-refractory multiple myeloma. A phase I/II Trial (SAKK 39/10)
Hitz F, Driessen C, Mey U, Samaras P, Vilei S, Stüdeli S, Rondeau S, Seipel K, Novak U, Silzle T, Besse L, Hess D, Pabst T, Kraus M, Swiss Group for Clinical Cancer Research SAKK. Nelfinavir and lenalidomide/dexamethasone in patients with lenalidomide-refractory multiple myeloma. A phase I/II Trial (SAKK 39/10). Blood Cancer J 2019; 9:70.
27.08.2019Nelfinavir and lenalidomide/dexamethasone in patients with lenalidomide-refractory multiple myeloma. A phase I/II Trial (SAKK 39/10)
27.08.2019Blood Cancer J 2019; 9:70
Hitz Felicitas, Driessen Christoph, Mey U, Samaras P, Vilei S Berardi, Stüdeli S, Rondeau S, Seipel K, Novak U, Silzle Tobias, Besse Lenka, Hess Dagmar, Pabst T, Kraus Marianne, Swiss Group for Clinical Cancer Research SAKK
Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer
Berner F, Hartmann F, Cheng H, Hönger G, Recher M, Goldman J, Cozzio A, Früh M, Neefjes J, Driessen C, Ludewig B, Hegazy A, Jochum W, Speiser D, Zippelius A, Läubli H, Bomze D, Diem S, Ali O, Fässler M, Ring S, Niederer R, Ackermann C, Baumgaertner P, Pikor N, Cruz C, van de Veen W, Akdis M, Nikolaev S, Flatz L. Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer. JAMA Oncol 2019; 5:1043-1047.
01.07.2019Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer
01.07.2019JAMA Oncol 2019; 5:1043-1047
Berner Fiamma, Hartmann Fabienne, Cheng Hung-Wei, Hönger Gideon, Recher Mike, Goldman Jonathan, Cozzio Antonio, Früh Martin, Neefjes Jacques, Driessen Christoph, Ludewig Burkhard, Hegazy Ahmed N, Jochum Wolfram, Speiser Daniel E, Zippelius Alfred, Läubli Heinz, Bomze David, Diem Stefan, Ali Omar Hasan, Fässler Mirjam, Ring Sandra, Niederer Rebekka, Ackermann Christoph J, Baumgaertner Petra, Pikor Natalia, Cruz Cristina Gil, van de Veen Willem, Akdis Mübeccel, Nikolaev Sergey, Flatz Lukas
Prevention, monitoring and treatment of cardiovascular adverse events in myeloma patients receiving carfilzomib A consensus paper by the European Myeloma Network and the Italian Society of Arterial Hypertension
Bringhen S, Ludwig H, Driessen C, Auner H, Caers J, Gramatzki M, Dimopoulos M, Boccadoro M, Einsele H, Sonneveld P, Cavo M, Goldschmidt H, Milan A, D'Agostino M, Ferri C, Wäsch R, Gay F, Larocca A, Offidani M, Zweegman S, Terpos E, Engelhardt M. Prevention, monitoring and treatment of cardiovascular adverse events in myeloma patients receiving carfilzomib A consensus paper by the European Myeloma Network and the Italian Society of Arterial Hypertension. J Intern Med 2019; 286:63-74.
08.04.2019Prevention, monitoring and treatment of cardiovascular adverse events in myeloma patients receiving carfilzomib A consensus paper by the European Myeloma Network and the Italian Society of Arterial Hypertension
08.04.2019J Intern Med 2019; 286:63-74
Bringhen S, Ludwig H, Driessen Christoph, Auner H W, Caers J, Gramatzki Martin, Dimopoulos M A, Boccadoro M, Einsele H, Sonneveld P, Cavo M, Goldschmidt H, Milan A, D'Agostino M, Ferri C, Wäsch R, Gay F, Larocca A, Offidani M, Zweegman S, Terpos E, Engelhardt M
Novel cell line models to study mechanisms and overcoming strategies of proteasome inhibitor resistance in multiple myeloma
Brünnert D, Kraus M, Stühmer T, Kirner S, Heiden R, Goyal P, Driessen C, Bargou R, Chatterjee M. Novel cell line models to study mechanisms and overcoming strategies of proteasome inhibitor resistance in multiple myeloma. Biochim Biophys Acta Mol Basis Dis 2019; 1865:1666-1676.
04.04.2019Novel cell line models to study mechanisms and overcoming strategies of proteasome inhibitor resistance in multiple myeloma
04.04.2019Biochim Biophys Acta Mol Basis Dis 2019; 1865:1666-1676
Brünnert Daniela, Kraus Marianne, Stühmer Thorsten, Kirner Stefanie, Heiden Robin, Goyal Pankaj, Driessen Christoph, Bargou Ralf C, Chatterjee Manik
Updated recommendations for diagnosis and treatment of plasma cell myeloma in Switzerland
Samaras P, Zander T, Taverna C, Schmidt A, Pabst T, Mey U, Matthes T, Lerch E, Ketterer N, Heim D, Duchosal M, Driessen C, Betticher D, Bargetzi M, Renner C. Updated recommendations for diagnosis and treatment of plasma cell myeloma in Switzerland. Swiss Med Wkly 2019; 149:w20031.
03.04.2019Updated recommendations for diagnosis and treatment of plasma cell myeloma in Switzerland
03.04.2019Swiss Med Wkly 2019; 149:w20031
Samaras Panagiotis, Zander Thilo, Taverna Christian, Schmidt Adrian, Pabst Thomas, Mey Ulrich, Matthes Thomas, Lerch Erika, Ketterer Nicolas, Heim Dominik, Duchosal Michel A, Driessen Christoph, Betticher Daniel C, Bargetzi Mario, Renner Christoph
Prolonged tumor response associated with sequential immune checkpoint inhibitor combination treatment and regorafenib in a patient with advanced pretreated hepatocellular carcinoma
Jörger M, Gueller U, Bastian S, Driessen C, von Moos R. Prolonged tumor response associated with sequential immune checkpoint inhibitor combination treatment and regorafenib in a patient with advanced pretreated hepatocellular carcinoma. J Gastrointest Oncol 2019; 10:373-378.
01.04.2019Prolonged tumor response associated with sequential immune checkpoint inhibitor combination treatment and regorafenib in a patient with advanced pretreated hepatocellular carcinoma
01.04.2019J Gastrointest Oncol 2019; 10:373-378
Jörger Markus, Gueller Ulrich, Bastian Sara, Driessen Christoph, von Moos Roger
Management of cardiovascular risk in patients with multiple myeloma
Plummer C, Driessen C, Szabo Z, Mateos M. Management of cardiovascular risk in patients with multiple myeloma. Blood Cancer J 2019; 9:26.
26.02.2019Management of cardiovascular risk in patients with multiple myeloma
26.02.2019Blood Cancer J 2019; 9:26
Plummer Chris, Driessen Christoph, Szabo Zsolt, Mateos Maria-Victoria
Replacement of miR-155 Elicits Tumor Suppressive Activity and Antagonizes Bortezomib Resistance in Multiple Myeloma
Amodio N, Tagliaferri P, Neri A, Driessen C, Rossi M, Ronchetti D, Caracciolo D, Federico C, Agosti V, Botta C, Gallo Cantafio M, Tassone P. Replacement of miR-155 Elicits Tumor Suppressive Activity and Antagonizes Bortezomib Resistance in Multiple Myeloma. Cancers (Basel) 2019; 11
18.02.2019Replacement of miR-155 Elicits Tumor Suppressive Activity and Antagonizes Bortezomib Resistance in Multiple Myeloma
18.02.2019Cancers (Basel) 2019; 11
Amodio Nicola, Tagliaferri Pierosandro, Neri Antonino, Driessen Christoph, Rossi Marco, Ronchetti Domenica, Caracciolo Daniele, Federico Cinzia, Agosti Valter, Botta Cirino, Gallo Cantafio Maria Eugenia, Tassone Pierfrancesco
Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits
Xin B, Groll M, van der Marel G, Driessen C, Florea B, Kisselev A, Weyburne E, Janssens M, Du Y, Espinal C, Maurits E, Heinemeyer W, de Bruin G, Huber E, Overkleeft H. Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits. J Med Chem 2019; 62:1626-1642.
05.02.2019Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits
05.02.2019J Med Chem 2019; 62:1626-1642
Xin Bo-Tao, Groll Michael, van der Marel Gijsbert A, Driessen Christoph, Florea Bogdan I, Kisselev Alexei F, Weyburne Emily S, Janssens Marissa, Du Yimeng, Espinal Christofer, Maurits Elmer, Heinemeyer Wolfgang, de Bruin Gerjan, Huber Eva M, Overkleeft Herman S