Prof. Dr. Burkhard Ludewig
Head, Institute of Immunobiology
Head, Medical Research Center
Head of clinic/institute/center
Medizinisches Forschungszentrum, Institute of Immunobiology · Management
Systems analysis reveals complex biological processes during virus infection fate decisions
Argilaguet J, Heath S, Ludewig B, Bocharov G, Kaisho T, Andreu D, Casella V, Gil Cruz C, Vidal E, Riera G, Esteve-Codina A, Pedragosa M, Meyerhans A. Systems analysis reveals complex biological processes during virus infection fate decisions. Genome Res 2019; 29:907-919.
May 28, 2019Systems analysis reveals complex biological processes during virus infection fate decisions
May 28, 2019Genome Res 2019; 29:907-919
Argilaguet Jordi, Heath Simon, Ludewig Burkhard, Bocharov Gennady, Kaisho Tsuneyasu, Andreu David, Casella Valentina, Gil Cruz Cristina, Vidal Enric, Riera Graciela, Esteve-Codina Anna, Pedragosa Mireia, Meyerhans Andreas
IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells
Dubey L, Ludewig B, Luther S, Harris N. IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells. Cell Rep 2019; 27:2442-2458.e5.
May 21, 2019IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells
May 21, 2019Cell Rep 2019; 27:2442-2458.e5
Dubey Lalit Kumar, Ludewig Burkhard, Luther Sanjiv A, Harris Nicola L
Divergent memory responses driven by adenoviral vectors are impacted by epitope competition
Colston J, Hutchings C, Chinnakannan S, Highton A, Perez Shibayama C, Ludewig B, Klenerman P. Divergent memory responses driven by adenoviral vectors are impacted by epitope competition. Eur J Immunol 2019
May 20, 2019Divergent memory responses driven by adenoviral vectors are impacted by epitope competition
May 20, 2019Eur J Immunol 2019
Colston Julia M, Hutchings Claire, Chinnakannan Senthil, Highton Andrew, Perez Shibayama Christian, Ludewig Burkhard, Klenerman Paul
Fibroblastic reticular cells at the nexus of innate and adaptive immune responses
Perez Shibayama C, Gil Cruz C, Ludewig B. Fibroblastic reticular cells at the nexus of innate and adaptive immune responses. Immunol Rev 2019; 289:31-41.
May 1, 2019Fibroblastic reticular cells at the nexus of innate and adaptive immune responses
May 1, 2019Immunol Rev 2019; 289:31-41
Perez Shibayama Christian, Gil Cruz Cristina, Ludewig Burkhard
Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
Cheng H, Hehlgans T, Rülicke T, Pfeffer K, Sorg U, Tersteegen A, Miyazaki J, Robinson M, Scandella E, Pikor N, Lütge M, Soneson C, Novkovic M, Onder L, Ludewig B. Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp. Nat Commun 2019; 10:1739.
Apr 15, 2019Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
Apr 15, 2019Nat Commun 2019; 10:1739
Cheng Hung-Wei, Hehlgans Thomas, Rülicke Thomas, Pfeffer Klaus, Sorg Ursula, Tersteegen Anne, Miyazaki Jun-Ichi, Robinson Mark D, Scandella Elke, Pikor Natalia, Lütge Mechthild, Soneson Charlotte, Novkovic Mario, Onder Lucas, Ludewig Burkhard
Rolf Zinkernagel and the co-discovery of MHC restriction together with Peter Doherty
Ludewig B. Rolf Zinkernagel and the co-discovery of MHC restriction together with Peter Doherty. Allergy 2019
Mar 27, 2019Rolf Zinkernagel and the co-discovery of MHC restriction together with Peter Doherty
Mar 27, 2019Allergy 2019
Ludewig Burkhard
TLR7 Controls VSV Replication in CD169 SCS Macrophages and Associated Viral Neuroinvasion
Solmaz G, Lang K, Wagner H, Clausen B, Ludewig B, Kalinke U, Khairnar V, Duhan V, Swallow M, Guderian M, Lindenberg M, Francozo M, Puttur F, Sparwasser T. TLR7 Controls VSV Replication in CD169 SCS Macrophages and Associated Viral Neuroinvasion. Front Immunol 2019; 10:466.
Mar 15, 2019TLR7 Controls VSV Replication in CD169 SCS Macrophages and Associated Viral Neuroinvasion
Mar 15, 2019Front Immunol 2019; 10:466
Solmaz Gülhas, Lang Karl S, Wagner Hermann, Clausen Björn E, Ludewig Burkhard, Kalinke Ulrich, Khairnar Vishal, Duhan Vikas, Swallow Maxine, Guderian Melanie, Lindenberg Marc, Francozo Marcela, Puttur Franz, Sparwasser Tim D
Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients
Fässler M, Jörger M, Recher M, Risch L, Güsewell S, Risch M, Speiser D, Ludewig B, Levesque M, Dummer R, Siano M, Krolik M, Diem S, Mangana J, Hasan Ali O, Berner F, Bomze D, Ring S, Niederer R, Gil Cruz C, Perez Shibayama C, Flatz L. Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients. J Immunother Cancer 2019; 7:50.
Feb 20, 2019Antibodies as biomarker candidates for response and survival to checkpoint inhibitors in melanoma patients
Feb 20, 2019J Immunother Cancer 2019; 7:50
Fässler Mirjam, Jörger Markus, Recher Mike, Risch Lorenz, Güsewell Sabine, Risch Martin, Speiser Daniel E, Ludewig Burkhard, Levesque Mitchell P, Dummer Reinhard, Siano Marco, Krolik Michal, Diem Stefan, Mangana Joanna, Hasan Ali Omar, Berner Fiamma, Bomze David, Ring Sandra, Niederer Rebekka, Gil Cruz Cristina, Perez Shibayama Christian, Flatz Lukas
Type I interferon induces CXCL13 to support ectopic germinal center formation
Denton A, Good-Jacobson K, Groom J, Ludewig B, Mörbe U, Mabbott N, Lafouresse F, Bradford B, Carr E, Innocentin S, Linterman M. Type I interferon induces CXCL13 to support ectopic germinal center formation. J Exp Med 2019
Feb 5, 2019Type I interferon induces CXCL13 to support ectopic germinal center formation
Feb 5, 2019J Exp Med 2019
Denton Alice E, Good-Jacobson Kim L, Groom Joanna R, Ludewig Burkhard, Mörbe Urs, Mabbott Neil A, Lafouresse Fanny, Bradford Barry M, Carr Edward J, Innocentin Silvia, Linterman Michelle A
Myocarditis Elicits Dendritic Cell and Monocyte Infiltration in the Heart and Self-Antigen Presentation by Conventional Type 2 Dendritic Cells
Van der Borght K, Gillebert T, Ludewig B, Boon L, Saeys Y, Nindl V, Van Isterdael G, Sichien D, Martens L, Scott C, Lambrecht B. Myocarditis Elicits Dendritic Cell and Monocyte Infiltration in the Heart and Self-Antigen Presentation by Conventional Type 2 Dendritic Cells. Front Immunol 2018; 9:2714.
Nov 21, 2018Myocarditis Elicits Dendritic Cell and Monocyte Infiltration in the Heart and Self-Antigen Presentation by Conventional Type 2 Dendritic Cells
Nov 21, 2018Front Immunol 2018; 9:2714
Van der Borght Katrien, Gillebert Thierry C, Ludewig Burkhard, Boon Louis, Saeys Yvan, Nindl Veronika, Van Isterdael Gert, Sichien Dorine, Martens Liesbet, Scott Charlotte L, Lambrecht Bart N
Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs
Bogdanova D, Takeuchi A, Ozawa M, Kanda Y, Rahman M, Ludewig B, Kinashi T, Katakai T. Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs. J Immunol 2018; 201:3580-3586.
Nov 5, 2018Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs
Nov 5, 2018J Immunol 2018; 201:3580-3586
Bogdanova Dana, Takeuchi Arata, Ozawa Madoka, Kanda Yasuhiro, Rahman M Azizur, Ludewig Burkhard, Kinashi Tatsuo, Katakai Tomoya
Redefining the Nature of Lymphoid Tissue Organizer Cells: Response to 'Complexity of Lymphoid Tissue Organizers' by Koning and Mebius
Onder L, Ludewig B. Redefining the Nature of Lymphoid Tissue Organizer Cells: Response to 'Complexity of Lymphoid Tissue Organizers' by Koning and Mebius. Trends Immunol 2018; 39:952-953.
Nov 2, 2018Redefining the Nature of Lymphoid Tissue Organizer Cells: Response to 'Complexity of Lymphoid Tissue Organizers' by Koning and Mebius
Nov 2, 2018Trends Immunol 2018; 39:952-953
Onder Lucas, Ludewig Burkhard
Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape
Novkovic M, Onder L, Cheng H, Bocharov G, Ludewig B. Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape. Front Immunol 2018; 9:2428.
Oct 23, 2018Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape
Oct 23, 2018Front Immunol 2018; 9:2428
Novkovic Mario, Onder Lucas, Cheng Hung-Wei, Bocharov Gennady, Ludewig Burkhard
A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node
Takeuchi A, Nagasawa T, Takahama Y, Ludewig B, Miyasaka M, Umemoto E, Shichida Y, Kawamura T, Rahman M, Kurosawa Y, Ohigashi I, Kozai M, Kanda Y, Ozawa M, Katakai T. A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node. Front Immunol 2018; 9:2196.
Oct 2, 2018A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node
Oct 2, 2018Front Immunol 2018; 9:2196
Takeuchi Arata, Nagasawa Takashi, Takahama Yousuke, Ludewig Burkhard, Miyasaka Masayuki, Umemoto Eiji, Shichida Yuto, Kawamura Toshihiko, Rahman Md Azizur, Kurosawa Yoichi, Ohigashi Izumi, Kozai Mina, Kanda Yasuhiro, Ozawa Madoka, Katakai Tomoya
A Fresh View on Lymph Node Organogenesis
Onder L, Ludewig B. A Fresh View on Lymph Node Organogenesis. Trends Immunol 2018; 39:775-787.
Aug 24, 2018A Fresh View on Lymph Node Organogenesis
Aug 24, 2018Trends Immunol 2018; 39:775-787
Onder Lucas, Ludewig Burkhard
Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity
Perez Shibayama C, Gommerman J, Scandella E, Robinson M, Soneson C, Mack M, Turley S, Buechler M, López-Macías C, Li C, Novkovic M, Mörbe U, Printz A, Onder L, Cheng H, Gil Cruz C, Ludewig B. Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity. Sci Immunol 2018; 3
Aug 10, 2018Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity
Aug 10, 2018Sci Immunol 2018; 3
Perez Shibayama Christian, Gommerman Jennifer, Scandella Elke, Robinson Mark D, Soneson Charlotte, Mack Matthias, Turley Shannon J, Buechler Matthew B, López-Macías Constantino, Li Conglei, Novkovic Mario, Mörbe Urs, Printz Andrea, Onder Lucas, Cheng Hung-Wei, Gil Cruz Cristina, Ludewig Burkhard
Tissue maintenance of CMV-specific inflationary memory T cells by IL-15
Baumann N, Ludewig B, Ikuta K, Cicin-Sain L, Oduro J, Pallmer K, Borsa M, Barnstorf I, Welten S, Torti N, Oxenius A. Tissue maintenance of CMV-specific inflationary memory T cells by IL-15. PLoS Pathog 2018; 14:e1006993.
Apr 13, 2018Tissue maintenance of CMV-specific inflationary memory T cells by IL-15
Apr 13, 2018PLoS Pathog 2018; 14:e1006993
Baumann Nicolas S, Ludewig Burkhard, Ikuta Koichi, Cicin-Sain Luka, Oduro Jennifer D, Pallmer Katharina, Borsa Mariana, Barnstorf Isabel, Welten Suzanne P M, Torti Nicole, Oxenius Annette
CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
Cheng H, Brutsche M, Jochum W, Schneider T, Rodriguez R, Tarantino I, Pikor N, Novkovic M, Bösch M, Cupovic J, Onder L, Ludewig B. CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses. J Allergy Clin Immunol 2018
Jan 31, 2018CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
Jan 31, 2018J Allergy Clin Immunol 2018
Cheng Hung-Wei, Brutsche Martin, Jochum Wolfram, Schneider Tino, Rodriguez Regulo, Tarantino Ignazio, Pikor Natalia, Novkovic Mario, Bösch Maximilian, Cupovic Jovana, Onder Lucas, Ludewig Burkhard
Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation
Emgård J, Svensson M, Scandella E, Hepworth M, Huber S, Ludewig B, Peduto L, Villablanca E, Veiga-Fernandes H, Pereira J, Flavell R, Kvedaraite E, Melo-Gonzalez F, Kammoun H, García-Cassani B, Chesné J, Parigi S, Jacob J, Cheng H, Evren E, Das S, Czarnewski P, Sleiers N, Willinger T. Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation. Immunity 2018; 48:120-132.e8.
Jan 16, 2018Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation
Jan 16, 2018Immunity 2018; 48:120-132.e8
Emgård Johanna, Svensson Mattias, Scandella Elke, Hepworth Matthew R, Huber Samuel, Ludewig Burkhard, Peduto Lucie, Villablanca Eduardo J, Veiga-Fernandes Henrique, Pereira João P, Flavell Richard A, Kvedaraite Egle, Melo-Gonzalez Felipe, Kammoun Hana, García-Cassani Bethania, Chesné Julie, Parigi Sara M, Jacob Jean-Marie, Cheng Hung-Wei, Evren Elza, Das Srustidhar, Czarnewski Paulo, Sleiers Natalie, Willinger Tim
Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness
Bösch M, Knauer M, Ruhstaller T, Jochum W, Gastl G, Sopper S, Mörbe U, Novkovic M, Cheng H, Onder L, Ludewig B. Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness. Oncoimmunology 2018; 7:e1414129.
Jan 3, 2018Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness
Jan 3, 2018Oncoimmunology 2018; 7:e1414129
Bösch Maximilian, Knauer Michael, Ruhstaller Thomas, Jochum Wolfram, Gastl Guenther, Sopper Sieghart, Mörbe Urs, Novkovic Mario, Cheng Hung-Wei, Onder Lucas, Ludewig Burkhard