Projekte
Suche in 1164 Projekten:
1164 Projekt(e)
ETATUS: Eye Tracking as an Assistance Tool in Ultrasound Training
01.01.2025
Grundlagenforschung - 01.01.2025 - 31.12.2025
Laufend
Projektleitung: Bektas Kenan
Mitarbeiter/innen: Ostendorp Carsten
PROtective ventilation with FLOW–controlled ventilation to improve postoperative pulmonary outcome after ROBOT–assisted laparoscopic surgery – an international multicenter pilot randomized clinical trial.
31.12.2024In einer internationalen, multizentrischen, randomisierten klinischen Pilotstudie wird die intraoperative flusskontrollierte Beatmung (FCV) mit der druckkontrollierten Beatmung (PCV) bei Patienten verglichen, die für eine roboterassistierte laparosko...
Klinische Forschung - 31.12.2024 - 31.03.2025
Geplant
Projektleitung: Yurttas Timur, Lüdi Markus
Assessment of Torque Teno Virus (TTV) viral load as marker for baseline immunity in healthcare workers
02.12.2024This project will retrospectively assess the association of SARS-CoV-2 vaccination status with TTV viral loads in a cohort of healthcare workers and correlation with susceptibility to respiratory infections, determined by total number of influenza-li...
Klinische Forschung - 02.12.2024 - 31.10.2025
Geplant
Projektleitung: Kohler Philipp
Mitarbeiter/innen: Kuster Stefan, Kahlert Christian, Grässli Fabian
SWISS TAVI
04.11.2024Prospective, National, Multi-Center Registry of Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) in Switzerland (SwissTAVI)
Register - 04.11.2024 - 30.12.2040
Laufend
Mitarbeiter/innen: Haager Philipp, Vetsch Susanne, Maeder Micha
Colchicine in Patients at Cardiac Risk undergoing Major Non-Cardiac Surgery: prospective, randomized, triple-blinded, placebo-controlled, multi-centre study
01.11.2024
Klinische Forschung - 01.11.2024 - 30.09.2027
Geplant
Projektleitung: Filipovic Miodrag, Yurttas Timur
Mitarbeiter/innen: Klein Carsten, Keller Mirja
Major adverse cardiovascular events in cancer patients during and after treatment with immune checkpoint inhibitors
01.11.2024
Klinische Forschung - 01.11.2024 - 31.10.2027
Geplant
Projektleitung: Daetwyler Eveline
Mitarbeiter/innen: Scheler Eva, Kuster Gabriela M, Zippelius Alfred, Rothschild Sacha I
Addition of Darolutamide to first line treatment of mCRPC: a randomized open label phase II trial.
31.10.2024
Klinische Forschung - 31.10.2024 - 31.12.2028
Laufend
Projektleitung: Fischer Stefanie
Mitarbeiter/innen: Dei Cas Alissa
AMG 355 20220028
17.10.2024Eine Phase-1-Studie am Menschen zur Bewertung der Sicherheit, Verträglichkeit, Pharmakokinetik und Wirksamkeit von AMG 355 als Monotherapie und in Kombination mit Pembrolizumab bei Patienten mit fortgeschrittenen soliden Tumoren
Klinische Forschung - 17.10.2024 - 31.12.2028
Laufend
Projektleitung: Jörger Markus
Mitarbeiter/innen: Donno Monica, Müller Fiona
SAKK 66/22 - Invincible 4 SAKK
17.10.2024Protocol SAKK 66/22: Intratumoral INT230-6 followed by neoadjuvant immunochemotherapy in patients with early triple-negative breast cancer (TNBC). An openlabel randomized two-cohort phase 2 clinical trial. INVINCIBLE-4-SAKK
Klinische Forschung - 17.10.2024 - 31.12.2029
Laufend
Projektleitung: Jörger Markus
Mitarbeiter/innen: Dei Cas Alissa, Müller Fiona
A comparison between the Swiss traffic perimetry (Swiss TPT) and the normal G2 strategy in automated perimetry: Observational cohort study
10.10.2024Current Swiss visual requirements for driving are under re-evaluation. The present study aims to optimize visual field evaluation in daily practice to better differentiate between people who are fit to drive and those who are not.
Klinische Forschung - 10.10.2024 - 31.10.2026
Laufend
Projektleitung: Todorova Margarita
A multicenter, open-label, randomized, phase 2 study of venetoclax and azacitidine plus cusatuzumab versus venetoclax and azacitidine alone in newly diagnosed AML patients who are not candidates for intensive therapy
07.10.2024
Klinische Forschung - 07.10.2024 - 09.10.2028
Laufend
Projektleitung: Schittenhelm Marcus
Mitarbeiter/innen: Dei Cas Alissa
A phase 3 randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of Amyloid Depleter ALXN2220 in adult participants with Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
01.10.2024
Klinische Forschung - 01.10.2024 - 31.12.2029
Geplant
Projektleitung: Ehl Niklas
Mitarbeiter/innen: Vetsch Susanne
MS201924_0002
30.09.2024An open-label, multicenter, randomized Phase 2 study of the ATR inhibitor tuvusertib in combination with the PARP inhibitor niraparib or the ATM inhibitor lartesertib in participants with BRCA mutant and/or homologous recombination deficiency (HRD) p...
Klinische Forschung - 30.09.2024 - 30.09.2028
Laufend
Projektleitung: Huober Jens
Mitarbeiter/innen: Dei Cas Alissa, Müller Fiona
Pulmonary Vein Isolation with Pulsed-Field Ablation with versus without Posterior wall ablation in Patients with Symptomatic Persistent Atrial Fibrillation
17.09.2024A multicentre randomised clinical trial comparing two ablation strategies for the treatment of persistent AF (PVI only or PVI+ posterior wall ablation). IC: persistent AF, (N)OAK EC: atrial interventions, o. atrium >60mm, TAVI, Ml, >NYHA III, LVEF...
Klinische Forschung - 17.09.2024 - 17.09.2027
Laufend
Projektleitung: Franzeck Florian M
Mitarbeiter/innen: Meier Jessica, Vetsch Susanne
Humoral immunity and risk factors for Alongshan-virus in healthcare workers from Eastern Switzerland –proposal for a seroepidemiologic analysis
01.08.2024In dieser prospektiven Studie innerhalb der SURPRISE+ Kohorte möchten wir die Seroprävalenz und Serokonversion gegen das Alongshan-Virus (ALSV). ALSV ist ein Flavivirus, welches ein FSME-ähnliches Krankheitsbild auslösen kann. Das Virus wird häufig i...
Klinische Forschung - 01.08.2024 - 28.02.2026
Laufend
Projektleitung: Kohler Philipp
Mitarbeiter/innen: Frischknecht Manuel, Kuster Stefan, Kahlert Christian
Textile ECG electrodes for long-term monitoring (Tex3CG)
01.07.2024The objective of this project is to evaluate and compare the signal quality of electrocardiogram (ECG) signals acquired by adhesive textile ECG electrodes (Tex) using adhesive gel electrodes (Gel) as a reference system.
Klinische Forschung - 01.07.2024 - 31.12.2024
Laufend
Projektleitung: Annaheim Simon, Ammann Peter
Mitarbeiter/innen: Meier Jessica
Hemodynamic characteristics of bendopnea – pathophysiological basis of a novel symptom in heart failure patients
01.07.2024The present project has several objectives. Our main goal is to evaluate the hemodynamic characteristics in particular the mean pulmonary artery wedge pressure (mPAWP) of patients with versus without bendopnea and those with high (supramedian) vers...
Klinische Forschung - 01.07.2024 - 30.06.2026
Laufend
Projektleitung: Maeder Micha
Mitarbeiter/innen: Schneider Irene
Influence of COVID-19 Pandemic on the Incidence of Acute Otitis Media with Complications: A Retrospective Cohort Study at a Tertiary Care Hospital
01.07.2024Acute otitis media (AOM) is typically a condition that resolves without long-term sequelae. However, it may be associated with complications. These can range from local complications such as involvement of the inner ear, potentially leading to persis...
Klinische Forschung - 01.07.2024 - 01.07.2025
Laufend
Projektleitung: Stöckli Sandro
Mitarbeiter/innen: Albrich Werner, Menegotto Richard
Metabolic acidosis: changes in bone mineral metabolism after bicarbonate treatment in kidney transplantation
01.07.2024Metabolic acidosis (MA) is a frequent complication in kidney transplantation (KTx). Chronic MA after KTx is associated with impaired mineral metabolism and growth retardation in children. After transplantation, skeletal health may be particularly sus...
Klinische Forschung - 01.07.2024 - 31.12.2025
Laufend
Mitarbeiter/innen: Ritter Alexander, Wagner Carsten A, Mohebbi Nilufar
A first-in-human, open-label, multicenter Phase l/ll study to evaluate the safety and anti-tumor activity of ANV600 as single agent and in combination with pembrolizumab in participants with advanced solid tumors (EXPAND-1)
13.06.2024
Klinische Forschung - 13.06.2024 - 31.12.2028
Laufend
Projektleitung: Jörger Markus
Mitarbeiter/innen: Sennhauser Andrina, Müller Fiona