Dr. Lucas Onder
Senior Scientist/Post-Doc at Institute of Immunobiology, Medical Research Center, Kantonsspital St. Gallen, Switzerland
wissenschaftliche(r) Mitarbeiter/in
Institut für Immunbiologie · Dept. Direktion
Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses
Fasnacht N, Luther S, Ludewig B, Tacchini-Cottier F, MacDonald H, Pinschewer D, Kallert S, Onder L, Chai Q, Auderset F, Favre S, Koch U, Huang H, Radtke F. Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses. J Exp Med 2014; 211:2265-79.
13.10.2014Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses
13.10.2014J Exp Med 2014; 211:2265-79
Fasnacht Nicolas, Luther Sanjiv A, Ludewig Burkhard, Tacchini-Cottier Fabienne, MacDonald H Robson, Pinschewer Daniel D, Kallert Sandra, Onder Lucas, Chai Qian, Auderset Floriane, Favre Stéphanie, Koch Ute, Huang Hsin-Ying, Radtke Freddy
B cell homeostasis and follicle confines are governed by fibroblastic reticular cells
Cremasco V, Carroll M, Ludewig B, Wucherpfennig K, Harvey C, Cremasco F, Chang J, Schildberg F, Nieves-Bonilla J, Cupovic J, Onder L, Woodruff M, Turley S. B cell homeostasis and follicle confines are governed by fibroblastic reticular cells. Nat Immunol 2014; 15:973-81.
24.08.2014B cell homeostasis and follicle confines are governed by fibroblastic reticular cells
24.08.2014Nat Immunol 2014; 15:973-81
Cremasco Viviana, Carroll Michael C, Ludewig Burkhard, Wucherpfennig Kai, Harvey Christopher J, Cremasco Floriana, Chang Jonathan, Schildberg Frank A, Nieves-Bonilla Janice M, Cupovic Jovana, Onder Lucas, Woodruff Matthew C, Turley Shannon J
IFN-γ-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi
Pérez Shibayama C, López-Macías C, Isibasi A, Waisman A, Regen T, Scandella E, Onder L, Chai Q, Hisaki E, Cervantes-Barragan L, Pastelin-Palacios R, Gil Cruz C, Ludewig B. IFN-γ-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi. J Immunol 2014; 192:5192-200.
28.04.2014IFN-γ-producing CD4+ T cells promote generation of protective germinal center-derived IgM+ B cell memory against Salmonella Typhi
28.04.2014J Immunol 2014; 192:5192-200
Pérez Shibayama Christian Ivan, López-Macías Constantino, Isibasi Armando, Waisman Ari, Regen Tommy, Scandella Elke, Onder Lucas, Chai Qian, Hisaki Emiliano, Cervantes-Barragan Luisa, Pastelin-Palacios Rodolfo, Gil Cruz Cristina, Ludewig Burkhard
Systemic minor histocompatibility antigen expression in blood endothelial cells prevents T cell-mediated vascular immunopathology
Caviezel-Firner S, Engeler D, Bolinger B, Onder L, Scandella E, Yu M, Kroczek R, Ludewig B. Systemic minor histocompatibility antigen expression in blood endothelial cells prevents T cell-mediated vascular immunopathology. Eur J Immunol 2013; 43:3233-43.
06.09.2013Systemic minor histocompatibility antigen expression in blood endothelial cells prevents T cell-mediated vascular immunopathology
06.09.2013Eur J Immunol 2013; 43:3233-43
Caviezel-Firner Sonja, Engeler Daniel, Bolinger Beatrice, Onder Lucas, Scandella Elke, Yu Meimei, Kroczek Richard A, Ludewig Burkhard
Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage
Iolyeva M, Finke D, Chen L, Boyman O, Santambrogio L, Ludewig B, Onder L, Krieg C, Bouchaud G, Häner S, Ecoiffier T, Willrodt A, Proulx S, Aebischer D, Halin C. Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage. Blood 2013; 122:2271-81.
20.08.2013Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage
20.08.2013Blood 2013; 122:2271-81
Iolyeva Maria, Finke Daniela, Chen Lu, Boyman Onur, Santambrogio Laura, Ludewig Burkhard, Onder Lucas, Krieg Carsten, Bouchaud Grégory, Häner Simone, Ecoiffier Tatiana, Willrodt Ann-Helen, Proulx Steven T, Aebischer David, Halin Cornelia
Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity
Chai Q, Hehlgans T, Stein J, Rülicke T, Thiel V, Luther S, Sparwasser T, Danuser R, Cupovic J, Pérez Shibayama C, Gil Cruz C, Scandella E, Onder L, Ludewig B. Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity 2013; 38:1013-24.
25.04.2013Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity
25.04.2013Immunity 2013; 38:1013-24
Chai Qian, Hehlgans Thomas, Stein Jens V, Rülicke Thomas, Thiel Volker, Luther Sanjiv A, Sparwasser Tim, Danuser Renzo, Cupovic Jovana, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Scandella Elke, Onder Lucas, Ludewig Burkhard
Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation.
Onder L, Danuser R, Scandella E, Firner S, Chai Q, Hehlgans T, Stein J, Ludewig B. Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation. J Exp Med 2013; 210:465-73.
18.02.2013Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation.
18.02.2013J Exp Med 2013; 210:465-73
Onder Lucas, Danuser Renzo, Scandella Elke, Firner Sonja, Chai Qian, Hehlgans Thomas, Stein Jens V, Ludewig Burkhard
IL-7-producing stromal cells are critical for lymph node remodeling
Onder L, Coles M, Cupedo T, Westermann J, Kaye P, Richie E, Halin C, Hoorweg K, Iolyeva M, Chai Q, Scandella E, Narang P, Ludewig B. IL-7-producing stromal cells are critical for lymph node remodeling. Blood 2012; 120:4675-83.
06.09.2012IL-7-producing stromal cells are critical for lymph node remodeling
06.09.2012Blood 2012; 120:4675-83
Onder Lucas, Coles Mark, Cupedo Tom, Westermann Jürgen, Kaye Paul, Richie Ellen, Halin Cornelia, Hoorweg Kerim, Iolyeva Maria, Chai Qian, Scandella Elke, Narang Priyanka, Ludewig Burkhard
Tight control - decision-making during T cell-vascular endothelial cell interaction.
Firner S, Onder L, Nindl V, Ludewig B. Tight control - decision-making during T cell-vascular endothelial cell interaction. Front Immunol 2012; 3:279.
27.08.2012Tight control - decision-making during T cell-vascular endothelial cell interaction.
27.08.2012Front Immunol 2012; 3:279
Firner Sonja, Onder Lucas, Nindl Veronika, Ludewig Burkhard
A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo.
Onder L, Scandella E, Chai Q, Firner S, Mayer C, Sparwasser T, Thiel V, Rülicke T, Ludewig B. A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo. Front Immunol 2011; 2:50.
12.10.2011A novel bacterial artificial chromosome-transgenic podoplanin-cre mouse targets lymphoid organ stromal cells in vivo.
12.10.2011Front Immunol 2011; 2:50
Onder Lucas, Scandella Elke, Chai Qian, Firner Sonja, Mayer Christian T, Sparwasser Tim, Thiel Volker, Rülicke Thomas, Ludewig Burkhard
Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway
Kumar V, Scandella E, Danuser R, Onder L, Nitschké M, Fukui Y, Halin C, Ludewig B, Stein J. Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway. Blood 2010; 115:4725-33.
10.06.2010Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway
10.06.2010Blood 2010; 115:4725-33
Kumar Varsha, Scandella Elke, Danuser Renzo, Onder Lucas, Nitschké Maximilian, Fukui Yoshinori, Halin Cornelia, Ludewig Burkhard, Stein Jens V
Immunopathological basis of lymphocytic choriomeningitis virus-induced chorioretinitis and keratitis
Zinkernagel M, Bolinger B, Krebs P, Onder L, Miller S, Ludewig B. Immunopathological basis of lymphocytic choriomeningitis virus-induced chorioretinitis and keratitis. Journal of virology 2009; 83:159-66.
01.01.2009Immunopathological basis of lymphocytic choriomeningitis virus-induced chorioretinitis and keratitis
01.01.2009Journal of virology 2009; 83:159-66
Zinkernagel Martin S, Bolinger Beatrice, Krebs Philippe, Onder Lucas, Miller Simone, Ludewig Burkhard