Dr. Lucas Onder
Senior Scientist/Post-Doc at Institute of Immunobiology, Medical Research Center, Kantonsspital St. Gallen, Switzerland
wissenschaftliche(r) Mitarbeiter/in
Institut für Immunbiologie · Dept. Direktion
Redefining the Nature of Lymphoid Tissue Organizer Cells: Response to 'Complexity of Lymphoid Tissue Organizers' by Koning and Mebius
Onder L, Ludewig B. Redefining the Nature of Lymphoid Tissue Organizer Cells: Response to 'Complexity of Lymphoid Tissue Organizers' by Koning and Mebius. Trends Immunol 2018; 39:952-953.
02.11.2018Redefining the Nature of Lymphoid Tissue Organizer Cells: Response to 'Complexity of Lymphoid Tissue Organizers' by Koning and Mebius
02.11.2018Trends Immunol 2018; 39:952-953
Onder Lucas, Ludewig Burkhard
Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape
Novkovic M, Onder L, Cheng H, Bocharov G, Ludewig B. Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape. Front Immunol 2018; 9:2428.
23.10.2018Integrative Computational Modeling of the Lymph Node Stromal Cell Landscape
23.10.2018Front Immunol 2018; 9:2428
Novkovic Mario, Onder Lucas, Cheng Hung-Wei, Bocharov Gennady, Ludewig Burkhard
A Fresh View on Lymph Node Organogenesis
Onder L, Ludewig B. A Fresh View on Lymph Node Organogenesis. Trends Immunol 2018; 39:775-787.
24.08.2018A Fresh View on Lymph Node Organogenesis
24.08.2018Trends Immunol 2018; 39:775-787
Onder Lucas, Ludewig Burkhard
Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity
Pérez Shibayama C, Gommerman J, Scandella E, Robinson M, Soneson C, Mack M, Turley S, Buechler M, López-Macías C, Li C, Novkovic M, Mörbe U, Printz A, Onder L, Cheng H, Gil Cruz C, Ludewig B. Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity. Sci Immunol 2018; 3
10.08.2018Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity
10.08.2018Sci Immunol 2018; 3
Pérez Shibayama Christian Ivan, Gommerman Jennifer, Scandella Elke, Robinson Mark D, Soneson Charlotte, Mack Matthias, Turley Shannon J, Buechler Matthew B, López-Macías Constantino, Li Conglei, Novkovic Mario, Mörbe Urs, Printz Andrea, Onder Lucas, Cheng Hung-Wei, Gil Cruz Cristina, Ludewig Burkhard
CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
Cheng H, Brutsche M, Jochum W, Schneider T, Rodriguez R, Tarantino I, Pikor N, Novkovic M, Bösch M, Cupovic J, Onder L, Ludewig B. CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses. J Allergy Clin Immunol 2018
31.01.2018CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
31.01.2018J Allergy Clin Immunol 2018
Cheng Hung-Wei, Brutsche Martin, Jochum Wolfram, Schneider Tino, Rodriguez Regulo, Tarantino Ignazio, Pikor Natalia, Novkovic Mario, Bösch Maximilian, Cupovic Jovana, Onder Lucas, Ludewig Burkhard
Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness
Bösch M, Knauer M, Ruhstaller T, Jochum W, Gastl G, Sopper S, Mörbe U, Novkovic M, Cheng H, Onder L, Ludewig B. Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness. Oncoimmunology 2018; 7:e1414129.
03.01.2018Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness
03.01.2018Oncoimmunology 2018; 7:e1414129
Bösch Maximilian, Knauer Michael, Ruhstaller Thomas, Jochum Wolfram, Gastl Guenther, Sopper Sieghart, Mörbe Urs, Novkovic Mario, Cheng Hung-Wei, Onder Lucas, Ludewig Burkhard
Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis
Onder L, Scandella E, Sawa S, Mueller C, Gommerman J, Rülicke T, Waisman A, Becher B, Pfeffer K, Hehlgans T, Cheng H, Novkovic M, Pikor N, Mörbe U, Ludewig B. Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity 2017; 47:80-92.e4.
11.07.2017Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis
11.07.2017Immunity 2017; 47:80-92.e4
Onder Lucas, Scandella Elke, Sawa Shinichiro, Mueller Christopher G, Gommerman Jennifer, Rülicke Thomas, Waisman Ari, Becher Burkhard, Pfeffer Klaus, Hehlgans Thomas, Cheng Hung-Wei, Novkovic Mario, Pikor Natalia, Mörbe Urs, Ludewig Burkhard
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands
Chung J, Onder L, Yan M, Reddy P, Blazar B, Huang A, Brennan T, Bishop D, Ludewig B, Siebel C, Radtke F, Luther S, Chai Q, Tran I, Ebens C, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Maillard I. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. J Clin Invest 2017; 127:1574-1588.
20.03.2017Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands
20.03.2017J Clin Invest 2017; 127:1574-1588
Chung Jooho, Onder Lucas, Yan Minhong, Reddy Pavan, Blazar Bruce R, Huang Alex Y, Brennan Todd V, Bishop D Keith, Ludewig Burkhard, Siebel Christian W, Radtke Freddy, Luther Sanjiv A, Chai Qian, Tran Ivy T, Ebens Christen L, Perkey Eric, Radojcic Vedran, Koch Ute, Scarpellino Leonardo, Tong Alexander, Allen Frederick, Wood Sherri, Feng Jiane, Friedman Ann, Granadier David, Maillard Ivan
Stromal Cell Niches in the Inflamed Central Nervous System
Pikor N, Cupovic J, Onder L, Gommerman J, Ludewig B. Stromal Cell Niches in the Inflamed Central Nervous System. J Immunol 2017; 198:1775-1781.
01.03.2017Stromal Cell Niches in the Inflamed Central Nervous System
01.03.2017J Immunol 2017; 198:1775-1781
Pikor Natalia, Cupovic Jovana, Onder Lucas, Gommerman Jennifer L, Ludewig Burkhard
Graph Theory-Based Analysis of the Lymph Node Fibroblastic Reticular Cell Network
Novkovic M, Onder L, Bocharov G, Ludewig B. Graph Theory-Based Analysis of the Lymph Node Fibroblastic Reticular Cell Network. Methods Mol Biol 2017; 1591:43-57.
01.01.2017Graph Theory-Based Analysis of the Lymph Node Fibroblastic Reticular Cell Network
01.01.2017Methods Mol Biol 2017; 1591:43-57
Novkovic Mario, Onder Lucas, Bocharov Gennady, Ludewig Burkhard
Critical Issues in Modelling Lymph Node Physiology
Grebennikov D, van Loon R, Novkovic M, Onder L, Savinkov R, Sazonov I, Tretyakova R, J Watson D, Bocharov G. Critical Issues in Modelling Lymph Node Physiology. Computation 2016; 5:3.
24.12.2016Critical Issues in Modelling Lymph Node Physiology
24.12.2016Computation 2016; 5:3
Grebennikov Dmitry, van Loon Raoul, Novkovic Mario, Onder Lucas, Savinkov Rostislav, Sazonov Igor, Tretyakova Rufina, J Watson Daniel, Bocharov Gennady
Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs
Gil Cruz C, Scandella E, Ikuta K, Cui G, Abe S, McCoy K, Geuking M, Lang P, Novkovic M, Cheng H, Cupovic J, Chai Q, Onder L, Pérez Shibayama C, Ludewig B. Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs. Nat Immunol 2016; 17:1388-1396.
31.10.2016Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs
31.10.2016Nat Immunol 2016; 17:1388-1396
Gil Cruz Cristina, Scandella Elke, Ikuta Koichi, Cui Guangwei, Abe Shinya, McCoy Kathy D, Geuking Markus B, Lang Philipp A, Novkovic Mario, Cheng Hung-Wei, Cupovic Jovana, Chai Qian, Onder Lucas, Pérez Shibayama Christian Ivan, Ludewig Burkhard
Data-driven modelling of the FRC network for studying the fluid flow in the conduit system
Savinkov R, Kislitsyn A, Watson D, van Loon R, Sazonov I, Novkovic M, Onder L, Bocharov G. Data-driven modelling of the FRC network for studying the fluid flow in the conduit system. Engineering Applications of Artificial Intelligence 2016; 62:341-349.
28.10.2016Data-driven modelling of the FRC network for studying the fluid flow in the conduit system
28.10.2016Engineering Applications of Artificial Intelligence 2016; 62:341-349
Savinkov Rostislav, Kislitsyn Alexey, Watson Daniel J., van Loon Raoul, Sazonov Igor, Novkovic Mario, Onder Lucas, Bocharov Gennady
Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
Novkovic M, Turley S, Bocharov G, Stein J, Scandella E, Cremasco V, Bomze D, Abe J, Cupovic J, Onder L, Ludewig B. Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality. PLoS Biol 2016; 14:e1002515.
14.07.2016Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
14.07.2016PLoS Biol 2016; 14:e1002515
Novkovic Mario, Turley Shannon J, Bocharov Gennady, Stein Jens V, Scandella Elke, Cremasco Viviana, Bomze David, Abe Jun, Cupovic Jovana, Onder Lucas, Ludewig Burkhard
Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation
Cupovic J, Onder L, Gil Cruz C, Weiler E, Caviezel-Firner S, Pérez Shibayama C, Rülicke T, Bechmann I, Ludewig B. Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation. Immunity 2016; 44:622-33.
23.02.2016Central Nervous System Stromal Cells Control Local CD8(+) T Cell Responses during Virus-Induced Neuroinflammation
23.02.2016Immunity 2016; 44:622-33
Cupovic Jovana, Onder Lucas, Gil Cruz Cristina, Weiler Elke, Caviezel-Firner Sonja, Pérez Shibayama Christian Ivan, Rülicke Thomas, Bechmann Ingo, Ludewig Burkhard
The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells
Mair F, Joller S, Hoeppli R, Onder L, Hahn M, Ludewig B, Waisman A, Becher B. The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells. Elife 2015; 4
05.12.2015The NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells
05.12.2015Elife 2015; 4
Mair Florian, Joller Stefanie, Hoeppli Romy, Onder Lucas, Hahn Matthias, Ludewig Burkhard, Waisman Ari, Becher Burkhard
Another TLO in the Wall: Education and Control of T Cells in Atherosclerotic Arteries
Onder L, Ludewig B. Another TLO in the Wall: Education and Control of T Cells in Atherosclerotic Arteries. Immunity 2015; 42:981-3.
16.06.2015Another TLO in the Wall: Education and Control of T Cells in Atherosclerotic Arteries
16.06.2015Immunity 2015; 42:981-3
Onder Lucas, Ludewig Burkhard
Computational Approach to 3D Modeling of the Lymph Node Geometry
Kislitsyn A, Savinkov R, Novkovic M, Onder L, Bocharov G. Computational Approach to 3D Modeling of the Lymph Node Geometry. Computation 2015; 3:222-234.
22.05.2015Computational Approach to 3D Modeling of the Lymph Node Geometry
22.05.2015Computation 2015; 3:222-234
Kislitsyn Alexey, Savinkov Rostislav, Novkovic Mario, Onder Lucas, Bocharov Gennady
Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction
Onder L, Waisman A, Becher B, Ledermann B, Mair F, Maier R, Bomze D, Novkovic M, Caviezel-Firner S, Cheng H, Chai Q, Scandella E, Nindl V, Ludewig B. Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction. Eur J Immunol 2015
14.05.2015Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction
14.05.2015Eur J Immunol 2015
Onder Lucas, Waisman Ari, Becher Burkhard, Ledermann Birgit, Mair Florian, Maier Reinhard, Bomze David, Novkovic Mario, Caviezel-Firner Sonja, Cheng Hung-Wei, Chai Qian, Scandella Elke, Nindl Veronika, Ludewig Burkhard
The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture
Astarita J, Xia L, Mooney D, Carroll M, Weimer R, Ludewig B, Onder L, Gogineni A, Woodruff M, Kondo Y, Song K, Nieves-Bonilla J, Peck J, Darnell M, Fu J, Cremasco V, Turley S. The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture. Nat Immunol 2014; 16:75-84.
27.10.2014The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture
27.10.2014Nat Immunol 2014; 16:75-84
Astarita Jillian L, Xia Lijun, Mooney David J, Carroll Michael C, Weimer Robby M, Ludewig Burkhard, Onder Lucas, Gogineni Alvin, Woodruff Matthew C, Kondo Yuji, Song Kai, Nieves-Bonilla Janice M, Peck James R, Darnell Max C, Fu Jianxin, Cremasco Viviana, Turley Shannon J