Prof. Dr. med. Stephan Brand
Gastroenterologie | Hepatologie · Dept. I
Macrophage migration inhibitory factor (MIF) -173G/C promoter polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease
Dambacher J, Lohse P, Ochsenkühn T, Göke B, Diebold J, Otte J, Tillack C, Konrad A, Hofbauer K, Pfennig S, Schnitzler F, Sisic Z, Seiderer J, Staudinger T, Brand S. Macrophage migration inhibitory factor (MIF) -173G/C promoter polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease. Inflamm Bowel Dis 2007; 13:71-82.
01.01.2007Macrophage migration inhibitory factor (MIF) -173G/C promoter polymorphism influences upper gastrointestinal tract involvement and disease activity in patients with Crohn's disease
01.01.2007Inflamm Bowel Dis 2007; 13:71-82
Dambacher Julia, Lohse Peter, Ochsenkühn Thomas, Göke Burkhard, Diebold Joachim, Otte Jan-Michel, Tillack Cornelia, Konrad Astrid, Hofbauer Katrin, Pfennig Simone, Schnitzler Fabian, Sisic Zeljka, Seiderer Julia, Staudinger Tanja, Brand Stephan
Chronisch entzündliche Darmerkrankungen: Morbus Crohn und Colitis ulcerosa
Brand S, Ochsenkühn T, Göke B. Chronisch entzündliche Darmerkrankungen: Morbus Crohn und Colitis ulcerosa. In: Gastroenterologie systematisch. Bremen: Uni-Med-Verlag, 2007.
01.01.2007Chronisch entzündliche Darmerkrankungen: Morbus Crohn und Colitis ulcerosa
01.01.2007Uni-Med-Verlag
Brand Stephan, Ochsenkühn T, Göke B
Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis
Seiderer J, Lohse P, Göke B, Sackmann M, Tillack C, Dambacher J, Hofbauer K, Herrmann K, Pfennig S, Staudinger T, Brand S, Schnitzler F, Ochsenkühn T. Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis. Scand J Gastroenterol 2006; 41:1421-32.
01.12.2006Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of re-stenosis
01.12.2006Scand J Gastroenterol 2006; 41:1421-32
Seiderer Julia, Lohse Peter, Göke Burkhard, Sackmann Michael, Tillack Cornelia, Dambacher Julia, Hofbauer Katrin, Herrmann Karin, Pfennig Simone, Staudinger Tanja, Brand Stephan, Schnitzler Fabian, Ochsenkühn Thomas
Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study
Seiderer J, Lohse P, Göke B, Schoenberg S, Pfennig S, Crispin A, Hatz R, Schnitzler F, Herrmann K, Brand S, Ochsenkühn T. Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study. Inflamm Bowel Dis 2006; 12:1114-21.
01.12.2006Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study
01.12.2006Inflamm Bowel Dis 2006; 12:1114-21
Seiderer Julia, Lohse Peter, Göke Burkhard, Schoenberg Stefan O, Pfennig Simone, Crispin Alexander, Hatz Rudolf, Schnitzler Fabian, Herrmann Karin A, Brand Stephan, Ochsenkühn Thomas
The +1059G/C polymorphism in the C-reactive protein (CRP) gene is associated with involvement of the terminal ileum and decreased serum CRP levels in patients with Crohn's disease
Thalmaier D, Lohse P, Ochsenkühn T, Göke B, Crispin A, Otte J, Pfennig S, Schachinger V, Konrad A, Seiderer J, Dambacher J, Brand S. The +1059G/C polymorphism in the C-reactive protein (CRP) gene is associated with involvement of the terminal ileum and decreased serum CRP levels in patients with Crohn's disease. Aliment Pharmacol Ther 2006; 24:1105-15.
01.10.2006The +1059G/C polymorphism in the C-reactive protein (CRP) gene is associated with involvement of the terminal ileum and decreased serum CRP levels in patients with Crohn's disease
01.10.2006Aliment Pharmacol Ther 2006; 24:1105-15
Thalmaier D, Lohse P, Ochsenkühn T, Göke B, Crispin A, Otte J-M, Pfennig S, Schachinger V, Konrad A, Seiderer J, Dambacher J, Brand Stephan
Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes
Glas J, Folwaczny M, Ochsenkühn T, Brand S, Schnitzler F, Seiderer J, Lohse P, Schiemann U, Griga T, Epplen J, Klein W, Wetzke M, Mussack T, Müller-Myhsok B, Tonenchi L, Török H, Folwaczny C. Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes. Inflamm Bowel Dis 2006; 12:606-11.
01.07.2006Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes
01.07.2006Inflamm Bowel Dis 2006; 12:606-11
Glas Jürgen, Folwaczny Matthias, Ochsenkühn Thomas, Brand Stephan, Schnitzler Fabian, Seiderer Julia, Lohse Peter, Schiemann Uwe, Griga Thomas, Epplen Joerg T, Klein Wolfram, Wetzke Martin, Mussack Thomas, Müller-Myhsok Bertram, Tonenchi Laurian, Török Helga-Paula, Folwaczny Christian
Low frequency of colorectal dysplasia in patients with long-standing inflammatory bowel disease colitis: detection by fluorescence endoscopy
Ochsenkühn T, Tillack C, Stepp H, Diebold J, Ott S, Baumgartner R, Brand S, Göke B, Sackmann M. Low frequency of colorectal dysplasia in patients with long-standing inflammatory bowel disease colitis: detection by fluorescence endoscopy. Endoscopy 2006; 38:477-82.
01.05.2006Low frequency of colorectal dysplasia in patients with long-standing inflammatory bowel disease colitis: detection by fluorescence endoscopy
01.05.2006Endoscopy 2006; 38:477-82
Ochsenkühn T, Tillack C, Stepp H, Diebold J, Ott S J, Baumgartner R, Brand Stephan, Göke B, Sackmann M
Nodular regenerative hyperplasia: a reversible entity associated with azathioprine therapy
Seiderer J, Zech C, Diebold J, Schoenberg S, Brand S, Tillack C, Göke B, Ochsenkühn T. Nodular regenerative hyperplasia: a reversible entity associated with azathioprine therapy. Eur J Gastroenterol Hepatol 2006; 18:553-5.
01.05.2006Nodular regenerative hyperplasia: a reversible entity associated with azathioprine therapy
01.05.2006Eur J Gastroenterol Hepatol 2006; 18:553-5
Seiderer Julia, Zech Christoph J, Diebold Joachim, Schoenberg Stefan O, Brand Stephan, Tillack Cornelia, Göke Burkhard, Ochsenkühn Thomas
Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells
Zitzmann K, Brand S, Baehs S, Göke B, Meinecke J, Spöttl G, Meyer H, Auernhammer C. Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells. Biochem Biophys Res Commun 2006; 344:1334-41.
24.04.2006Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells
24.04.2006Biochem Biophys Res Commun 2006; 344:1334-41
Zitzmann Kathrin, Brand Stephan, Baehs Sebastian, Göke Burkhard, Meinecke Jennifer, Spöttl Gerald, Meyer Heinrich, Auernhammer Christoph J
IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
Brand S, Auernhammer C, Göke B, Ochsenkühn T, Seiderer J, Herrmann K, Leclair S, Popp A, Jagla W, Marquardt A, Diepolder H, Otte J, Eichhorst S, Zitzmann K, Olszak T, Beigel F, Dambacher J. IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. Am J Physiol Gastrointest Liver Physiol 2006; 290:G827-38.
01.04.2006IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
01.04.2006Am J Physiol Gastrointest Liver Physiol 2006; 290:G827-38
Brand Stephan, Auernhammer Christoph J, Göke Burkhard, Ochsenkühn Thomas, Seiderer Julia, Herrmann Karin, Leclair Stéphane, Popp Andreas, Jagla Wolfgang, Marquardt Andreas, Diepolder Helmut, Otte Jan-Michel, Eichhorst Sören T, Zitzmann Kathrin, Olszak Torsten, Beigel Florian, Dambacher Julia
Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells
Brand S, Olszak T, Beigel F, Diebold J, Otte J, Eichhorst S, Göke B, Dambacher J. Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells. J Cell Biochem 2006; 97:709-23.
01.03.2006Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells
01.03.2006J Cell Biochem 2006; 97:709-23
Brand Stephan, Olszak Torsten, Beigel Florian, Diebold Joachim, Otte Jan-Michel, Eichhorst Soeren T, Göke Burkhard, Dambacher Julia
Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease
Schnitzler F, Ochsenkühn T, Göke B, Tillack C, Seiderer J, Hofbauer K, Pfennig S, Staudinger T, Brand S, Lohse P. Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease. Immunogenetics 2006; 58:99-106.
17.02.2006Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease
17.02.2006Immunogenetics 2006; 58:99-106
Schnitzler Fabian, Ochsenkühn Thomas, Göke Burkhard, Tillack Cornelia, Seiderer Julia, Hofbauer Katrin, Pfennig Simone, Staudinger Tanja, Brand Stephan, Lohse Peter
Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype
Brand S, Ochsenkühn T, Göke B, Konrad A, Tillack C, Seiderer J, Pfennig S, Staudinger T, Schnitzler F, Dambacher J, Hofbauer K, Lohse P. Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype. Am J Gastroenterol 2006; 101:99-106.
01.01.2006Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease Phenotype
01.01.2006Am J Gastroenterol 2006; 101:99-106
Brand Stephan, Ochsenkühn Thomas, Göke Burkhard, Konrad Astrid, Tillack Cornelia, Seiderer Julia, Pfennig Simone, Staudinger Tanja, Schnitzler Fabian, Dambacher Julia, Hofbauer Katrin, Lohse Peter
CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation
Brand S, Dambacher J, Beigel F, Olszak T, Diebold J, Otte J, Göke B, Eichhorst S. CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation. Exp Cell Res 2005; 310:117-30.
15.10.2005CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation
15.10.2005Exp Cell Res 2005; 310:117-30
Brand Stephan, Dambacher Julia, Beigel Florian, Olszak Torsten, Diebold Joachim, Otte Jan-Michel, Göke Burkhard, Eichhorst Sören T
Infliximab zur Therapie chronisch entzündlicher Darmerkrankungen
Seiderer J, Schnitzler F, Brand S, Tillack C, Göke B, Ochsenkühn T. Infliximab zur Therapie chronisch entzündlicher Darmerkrankungen. Dtsch Arztebl 2005; 102:828-833.
04.10.2005Infliximab zur Therapie chronisch entzündlicher Darmerkrankungen
04.10.2005Dtsch Arztebl 2005; 102:828-833
Seiderer J, Schnitzler F, Brand Stephan, Tillack C, Göke B, Ochsenkühn T
The Novel Lambda-Interferons IL-28A and IL-29 Mediate Proinflammatory, Antiproliferative, and Antiviral Signals in Intestinal Epithelial Cells
Brand S, Auernhammer C, Adler B, Diepolder H, Göke B, Otte J, Eichhorst S, Zitzmann K, Olszak T, Beigel F, Dambacher J. The Novel Lambda-Interferons IL-28A and IL-29 Mediate Proinflammatory, Antiproliferative, and Antiviral Signals in Intestinal Epithelial Cells. Gastroenterology 2005; 129:371-371.
04.10.2005The Novel Lambda-Interferons IL-28A and IL-29 Mediate Proinflammatory, Antiproliferative, and Antiviral Signals in Intestinal Epithelial Cells
04.10.2005Gastroenterology 2005; 129:371-371
Brand Stephan, Auernhammer Christoph J, Adler Barbara, Diepolder Helmut, Göke B, Otte J-M, Eichhorst Soeren T, Zitzmann K, Olszak Torsten, Beigel F, Dambacher J
IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression
Brand S, Göke B, Auernhammer C, Adler B, Diepolder H, Diebold J, Otte J, Eichhorst S, Zitzmann K, Olszak T, Beigel F, Dambacher J. IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression. Am J Physiol Gastrointest Liver Physiol 2005; 289:G960-8.
28.07.2005IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression
28.07.2005Am J Physiol Gastrointest Liver Physiol 2005; 289:G960-8
Brand Stephan, Göke Burkhard, Auernhammer Christoph J, Adler Barbara, Diepolder Helmut, Diebold Joachim, Otte Jan-Michel, Eichhorst Sören T, Zitzmann Kathrin, Olszak Torsten, Beigel Florian, Dambacher Julia
The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease
Brand S, Lohse P, Göke B, Crispin A, Konrad A, Tillack C, Seiderer J, Dambacher J, Hofbauer K, Pfennig S, Schnitzler F, Staudinger T, Ochsenkühn T. The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease. Inflamm Bowel Dis 2005; 11:645-52.
01.07.2005The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease
01.07.2005Inflamm Bowel Dis 2005; 11:645-52
Brand Stephan, Lohse Peter, Göke Burkhard, Crispin Alexander, Konrad Astrid, Tillack Cornelia, Seiderer Julia, Dambacher Julia, Hofbauer Katrin, Pfennig Simone, Schnitzler Fabian, Staudinger Tanja, Ochsenkühn Thomas
Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease
Török H, Brünnler G, Jagiello P, Epplen J, Griga T, Klein W, Schiemann U, Folwaczny M, Ochsenkühn T, Brand S, Tillack C, Glas J, Tonenchi L, Lohse P, Müller-Myhsok B, Limbersky O, Neugebauer C, Schnitzler F, Seiderer J, Folwaczny C. Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease. Gut 2005; 54:1421-7.
14.06.2005Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease
14.06.2005Gut 2005; 54:1421-7
Török H-P, Brünnler G, Jagiello P, Epplen J T, Griga T, Klein W, Schiemann U, Folwaczny M, Ochsenkühn T, Brand Stephan, Tillack C, Glas J, Tonenchi L, Lohse P, Müller-Myhsok B, Limbersky O, Neugebauer C, Schnitzler F, Seiderer J, Folwaczny C
SOCS-1 inhibits expression of the antiviral proteins 2',5'-OAS and MxA induced by the novel interferon-lambdas IL-28A and IL-29
Brand S, Diepolder H, Göke B, Eichhorst S, Vlotides G, Olszak T, Beigel F, Dambacher J, Zitzmann K, Auernhammer C. SOCS-1 inhibits expression of the antiviral proteins 2',5'-OAS and MxA induced by the novel interferon-lambdas IL-28A and IL-29. Biochem Biophys Res Commun 2005; 331:543-8.
03.06.2005SOCS-1 inhibits expression of the antiviral proteins 2',5'-OAS and MxA induced by the novel interferon-lambdas IL-28A and IL-29
03.06.2005Biochem Biophys Res Commun 2005; 331:543-8
Brand Stephan, Diepolder Helmut, Göke Burkhard, Eichhorst Sören T, Vlotides George, Olszak Torsten, Beigel Florian, Dambacher Julia, Zitzmann Kathrin, Auernhammer Christoph J