Prof. Dr. med. Stephan Brand
Gastroenterologie | Hepatologie · Dept. I
Role of PPARG gene variants in inflammatory bowel disease
Glas J, Roeske D, Diegelmann J, Müller-Myhsok B, Ochsenkühn T, Göke B, Paschos E, Wetzke M, Pfennig S, Markus C, Seiderer J, Brand S. Role of PPARG gene variants in inflammatory bowel disease. Inflamm Bowel Dis 2010; 17:1057-8.
18.08.2010Role of PPARG gene variants in inflammatory bowel disease
18.08.2010Inflamm Bowel Dis 2010; 17:1057-8
Glas Jürgen, Roeske Darina, Diegelmann Julia, Müller-Myhsok Bertram, Ochsenkühn Thomas, Göke Burkhard, Paschos Ekaterini, Wetzke Martin, Pfennig Simone, Markus Christian, Seiderer Julia, Brand Stephan
Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset
Glas J, Roeske D, Müller-Myhsok B, Diegelmann J, Ochsenkühn T, Göke B, Folwaczny M, Lohse P, Epplen J, Klein W, Pfennig S, Weidinger M, Beigel F, Fries C, Nagy M, Seiderer J, Brand S. Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset. PloS one 2010; 5:e10373.
29.04.2010Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset
29.04.2010PloS one 2010; 5:e10373
Glas Jürgen, Roeske Darina, Müller-Myhsok Bertram, Diegelmann Julia, Ochsenkühn Thomas, Göke Burkhard, Folwaczny Matthias, Lohse Peter, Epplen Jörg T, Klein Wolfram, Pfennig Simone, Weidinger Maria, Beigel Florian, Fries Christoph, Nagy Melinda, Seiderer Julia, Brand Stephan
The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype
Jürgens M, Herrmann K, Lohse P, Göke B, Kreis M, Schnitzler F, Weidinger M, Beigel F, Tillack C, Pfennig S, Wagner J, Wetzke M, Glas J, Seiderer J, Laubender R, Brand S, Ochsenkühn T. The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype. J Gastroenterol 2010; 45:721-31.
29.04.2010The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype
29.04.2010J Gastroenterol 2010; 45:721-31
Jürgens Matthias, Herrmann Karin, Lohse Peter, Göke Burkhard, Kreis Martin E, Schnitzler Fabian, Weidinger Maria, Beigel Florian, Tillack Cornelia, Pfennig Simone, Wagner Johanna, Wetzke Martin, Glas Jürgen, Seiderer Julia, Laubender Rüdiger P, Brand Stephan, Ochsenkühn Thomas
Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease
Zitzmann K, Rüden J, Brand S, Göke B, Lichtl J, Spöttl G, Auernhammer C. Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease. Cancer Lett 2010; 295:100-9.
30.03.2010Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease
30.03.2010Cancer Lett 2010; 295:100-9
Zitzmann Kathrin, Rüden Janina von, Brand Stephan, Göke Burkhard, Lichtl Jennifer, Spöttl Gerald, Auernhammer Christoph J
Augmenter of liver regeneration causes different kinetics of ERK1/2 and Akt/PKB phosphorylation than EGF and induces hepatocyte proliferation in an EGF receptor independent and liver specific manner
Ilowski M, Putz C, Weiss T, Brand S, Jauch K, Hengstler J, Thasler W. Augmenter of liver regeneration causes different kinetics of ERK1/2 and Akt/PKB phosphorylation than EGF and induces hepatocyte proliferation in an EGF receptor independent and liver specific manner. Biochem Biophys Res Commun 2010; 394:915-20.
15.03.2010Augmenter of liver regeneration causes different kinetics of ERK1/2 and Akt/PKB phosphorylation than EGF and induces hepatocyte proliferation in an EGF receptor independent and liver specific manner
15.03.2010Biochem Biophys Res Commun 2010; 394:915-20
Ilowski Maren, Putz Christine, Weiss Thomas S, Brand Stephan, Jauch Karl-Walter, Hengstler Jan G, Thasler Wolfgang Erwin
Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis
Jürgens M, Ochsenkühn T, Glas J, Göke B, Lohse P, Tillack C, Schnitzler F, Stallhofer J, Pfennig S, Beigel F, Wetzke M, Wagner J, Seiderer J, Weidinger M, Hartl F, Laubender R, Brand S. Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis. Am J Gastroenterol 2010; 105:1811-9.
02.03.2010Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis
02.03.2010Am J Gastroenterol 2010; 105:1811-9
Jürgens Matthias, Ochsenkühn Thomas, Glas Jürgen, Göke Burkhard, Lohse Peter, Tillack Cornelia, Schnitzler Fabian, Stallhofer Johannes, Pfennig Simone, Beigel Florian, Wetzke Martin, Wagner Johanna, Seiderer Julia, Weidinger Maria, Hartl Franziska, Laubender Rüdiger P, Brand Stephan
The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease
Storr M, Emmerdinger D, Diegelmann J, Pfennig S, Ochsenkühn T, Göke B, Lohse P, Brand S. The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease. PloS one 2010; 5:e9453.
26.02.2010The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease
26.02.2010PloS one 2010; 5:e9453
Storr Martin, Emmerdinger Dominik, Diegelmann Julia, Pfennig Simone, Ochsenkühn Thomas, Göke Burkhard, Lohse Peter, Brand Stephan
Severe Legionella pneumophila pneumonia following infliximab therapy in a patient with Crohn's disease
Beigel F, Jürgens M, Filik L, Bader L, Lück C, Göke B, Ochsenkühn T, Brand S, Seiderer J. Severe Legionella pneumophila pneumonia following infliximab therapy in a patient with Crohn's disease. Inflamm Bowel Dis 2009; 15:1240-4.
01.08.2009Severe Legionella pneumophila pneumonia following infliximab therapy in a patient with Crohn's disease
01.08.2009Inflamm Bowel Dis 2009; 15:1240-4
Beigel Florian, Jürgens Matthias, Filik Levent, Bader Lutz, Lück Christian, Göke Burkhard, Ochsenkühn Thomas, Brand Stephan, Seiderer Julia
Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease
Brand S. Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease. Gut 2009; 58:1152-67.
01.08.2009Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease
01.08.2009Gut 2009; 58:1152-67
Brand Stephan
Hepatosplenic T-cell lymphoma in a patient with Crohn's disease
Beigel F, Jürgens M, Tillack C, Subklewe M, Mayr D, Göke B, Brand S, Ochsenkühn T. Hepatosplenic T-cell lymphoma in a patient with Crohn's disease. Nat Rev Gastroenterol Hepatol 2009; 6:433-6.
01.07.2009Hepatosplenic T-cell lymphoma in a patient with Crohn's disease
01.07.2009Nat Rev Gastroenterol Hepatol 2009; 6:433-6
Beigel Florian, Jürgens Matthias, Tillack Cornelia, Subklewe Marion, Mayr Doris, Göke Burkhard, Brand Stephan, Ochsenkühn Thomas
Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease
Török H, Müller-Myhsok B, Folwaczny C, Göke B, Folwaczny M, Ochsenkühn T, Lohse P, Klein W, Wetzke M, Teshome M, Tonenchi L, Endres I, Glas J, Brand S. Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease. Am J Gastroenterol 2009; 104:1723-33.
19.05.2009Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease
19.05.2009Am J Gastroenterol 2009; 104:1723-33
Török Helga P, Müller-Myhsok Bertram, Folwaczny Christian, Göke Burkhard, Folwaczny Matthias, Ochsenkühn Thomas, Lohse Peter, Klein Wolfram, Wetzke Martin, Teshome Molla Y, Tonenchi Laurian, Endres Ilona, Glas Jürgen, Brand Stephan
Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease
Glas J, Müller-Myhsok B, Ochsenkühn T, Göke B, Lohse P, Folwaczny M, Koletzko S, Lacher M, Schiemann U, Griga T, Epplen J, Klein W, Pfennig S, Wetzke M, Ripke S, Stallhofer J, Brand S. Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease. Am J Gastroenterol 2009; 104:1737-44.
19.05.2009Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease
19.05.2009Am J Gastroenterol 2009; 104:1737-44
Glas Jürgen, Müller-Myhsok Bertram, Ochsenkühn Thomas, Göke Burkhard, Lohse Peter, Folwaczny Matthias, Koletzko Sibylle, Lacher Martin, Schiemann Uwe, Griga Thomas, Epplen Jörg T, Klein Wolfram, Pfennig Simone, Wetzke Martin, Ripke Stephan, Stallhofer Johannes, Brand Stephan
Effects of the cathelicidin LL-37 on intestinal epithelial barrier integrity
Otte J, Zdebik A, Brand S, Chromik A, Strauss S, Schmitz F, Steinstraesser L, Schmidt W. Effects of the cathelicidin LL-37 on intestinal epithelial barrier integrity. Regul Pept 2009; 156:104-17.
26.03.2009Effects of the cathelicidin LL-37 on intestinal epithelial barrier integrity
26.03.2009Regul Pept 2009; 156:104-17
Otte Jan-Michel, Zdebik Anna-Elisabeth, Brand Stephan, Chromik Ansgar M, Strauss Sarah, Schmitz Frank, Steinstraesser Lars, Schmidt Wolfgang E
IL-22: a two-headed cytokine in IBD?
Seiderer J, Brand S. IL-22: a two-headed cytokine in IBD?. Inflamm Bowel Dis 2009; 15:473-4.
01.03.2009IL-22: a two-headed cytokine in IBD?
01.03.2009Inflamm Bowel Dis 2009; 15:473-4
Seiderer Julia, Brand Stephan
rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population
Glas J, Klein W, Epplen J, Schiemann U, Mussack T, Lohse P, Göke B, Ochsenkühn T, Folwaczny M, Müller-Myhsok B, Griga T, Jürgens M, Stallhofer J, Seiderer J, Pasciuto G, Tillack C, Diegelmann J, Pfennig S, Konrad A, Schmechel S, Wetzke M, Török H, Brand S. rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2009; 104:665-72.
03.02.2009rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population
03.02.2009Am J Gastroenterol 2009; 104:665-72
Glas Jürgen, Klein Wolfram, Epplen Jörg T, Schiemann Uwe, Mussack Thomas, Lohse Peter, Göke Burkhard, Ochsenkühn Thomas, Folwaczny Matthias, Müller-Myhsok Bertram, Griga Thomas, Jürgens Matthias, Stallhofer Johannes, Seiderer Julia, Pasciuto Giulia, Tillack Cornelia, Diegelmann Julia, Pfennig Simone, Konrad Astrid, Schmechel Silke, Wetzke Martin, Török Helga-Paula, Brand Stephan
Expression of beta-defensin 4 is increased in human gastritis
Otte J, Neumann H, Brand S, Schrader H, Schmidt W, Schmitz F. Expression of beta-defensin 4 is increased in human gastritis. Eur J Clin Invest 2009; 39:126-38.
01.02.2009Expression of beta-defensin 4 is increased in human gastritis
01.02.2009Eur J Clin Invest 2009; 39:126-38
Otte J-M, Neumann H M, Brand Stephan, Schrader H, Schmidt W E, Schmitz F
Probiotics regulate the expression of COX-2 in intestinal epithelial cells
Otte J, Mahjurian-Namari R, Brand S, Werner I, Schmidt W, Schmitz F. Probiotics regulate the expression of COX-2 in intestinal epithelial cells. Nutr Cancer 2009; 61:103-13.
01.01.2009Probiotics regulate the expression of COX-2 in intestinal epithelial cells
01.01.2009Nutr Cancer 2009; 61:103-13
Otte Jan-Michel, Mahjurian-Namari Rudja, Brand Stephan, Werner Ilka, Schmidt Wolfgang E, Schmitz Frank
Sicherheit von anti-TNF-Antikörper-Therapien
Seiderer J, Brand S, Kaser A. Sicherheit von anti-TNF-Antikörper-Therapien. In: Zytokine und chronisch-entzündliche Darmerkrankungen - Pathogenese und Therapie. Bremen: Uni-Med-Verlag, 2009.
01.01.2009Sicherheit von anti-TNF-Antikörper-Therapien
01.01.2009Uni-Med-Verlag
Seiderer J, Brand Stephan, Kaser Arthur
The role of fatty acid hydrolase gene variants in inflammatory bowel disease
Storr M, Emmerdinger D, Diegelmann J, Yüce B, Pfennig S, Ochsenkühn T, Göke B, Lohse P, Brand S. The role of fatty acid hydrolase gene variants in inflammatory bowel disease. Aliment Pharmacol Ther 2008; 29:542-51.
02.12.2008The role of fatty acid hydrolase gene variants in inflammatory bowel disease
02.12.2008Aliment Pharmacol Ther 2008; 29:542-51
Storr M, Emmerdinger D, Diegelmann J, Yüce B, Pfennig S, Ochsenkühn T, Göke B, Lohse P, Brand Stephan
Bauchschmerzen nach dem Oktoberfest (Fallbericht zur Peritonealtuberkulose)
Beigel F, Nicolaus M, Denk G, Wagner A, Brand S. Bauchschmerzen nach dem Oktoberfest (Fallbericht zur Peritonealtuberkulose). Gastroenterologe 2008:144-146.
04.10.2008Bauchschmerzen nach dem Oktoberfest (Fallbericht zur Peritonealtuberkulose)
04.10.2008Gastroenterologe 2008:144-146
Beigel F, Nicolaus M, Denk Gerald Ulrich, Wagner A, Brand Stephan