Projekte
Suche in 1157 Projekten:
1157 Projekt(e)
Resistance Development in Escherichia coli at different pH following Delafloxacin and Ciprofloxacin Challenge
01.01.2021Delafloxacin , a novel dual-targeting non-zwitterionic fluoroquinolone, has received approval by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for the treatment of acute bacterial skin and skin structure infectio...
Grundlagenforschung - 01.01.2021 - 01.01.2023
Automatisch geschlossen
Projektleitung: Babouee Flury Baharak
Translation of pre-treatment tumor kinetics and clinical and serological markers of the immune system in the treatment of advanced melanoma
01.01.2021Bei diesem Projekt geht es um die Charakterisierung des Therapieansprechens von Melanommetastasen unter Systemtherapie mit anti-PD-1 Antikörpern, kombinierter Immuntherapie mit dem anti-PD-1 Antikörper Nivolumab und dem anti-CTLA-4 Antikörper Ipilimu...
Klinische Forschung - 01.01.2021 - 31.12.2021
Abgeschlossen
Projektleitung: Wagner Nikolaus
Decision-Making Analysis of next generation sequencing in glioblastoma in Switzerland
01.01.2021Glioblastoma is the most frequent and most malignant primary brain tumour with an annual incidence of 3.2/100’000 1,2. The combination of histopathological features (nuclear atypia, mitosis, neoangiogenesis and/or necrosis) and molecular aberrations...
Klinische Forschung - 01.01.2021 - 01.12.2021
Automatisch geschlossen
Mitarbeiter/innen: Putora Paul Martin
Towards identification of novel therapeutic targets: Assessment of proteasome-related alterations in MM patients’ datasets
01.01.2021
Grundlagenforschung - 01.01.2021 - 31.12.2021
Automatisch geschlossen
Projektleitung: Besse Lenka, Buljan Marija
Mitarbeiter/innen: Besse Andrej
Clinical evaluation of a standard treatment algorithm for midshaft clavicle fractures
01.01.2021The aim of this research project is to evaluate the evidence-based treatment standard for patients with midshaft clavicle fractures using an algorithmic approach in a Swiss multi-centre, prospective data collection. This algorithm includes not only t...
Register - 01.01.2021 - 31.12.2025
Laufend
Projektleitung: Spross Christian
Mitarbeiter/innen: Jost Bernhard, Zdravkovic Vilijam, Schöfl Thomas, Farei-Campagna Jan M
Diagnostic role of the "white test" with lipidic solution in the early intraoperative identification of open bile ducts for the prevention of bile leakage after liver resection - A randomized controlled multicentric superiority trial.
01.01.2021Bile leakage (BL) is the most frequent complication after liver resection leading to the need of interventional drainage, ERCP or even reoperation. Strategies leading to a reduction of the rate of this complication are valuable. SMOFlipid 20% is a fa...
Klinische Forschung - 01.01.2021 - 31.12.2024
Laufend
Projektleitung: Tarantino Ignazio
Swiss Soliris® and Ultomiris® Reimbursement Registry SSURR: An observational registry for capturing data of patients suffering from paroxysmal nocturnal hemoglobinuria (PNH) who are treated with Soliris® (eculizumab) or Ultomiris® (ravulizumab)
01.01.2021
Klinische Forschung - 01.01.2021 - 31.12.2030
Laufend
Projektleitung: Silzle Tobias
Mitarbeiter/innen: Demmer-Steingruber Ruth, Müller Fiona
Swiss Primary Hypersomnolence and Narcolepsy Cohort Study
01.01.2021
Klinische Forschung - 01.01.2021 - 31.12.2023
Abgeschlossen
Projektleitung: Von Manitius Sigrid
Mitarbeiter/innen: Zieglgänsberger Dominik, Gievers-Steinlein Bettina
CATCH - Cascade genetic testing of familial hypercholesterolemia: the CATCH multicenter randomized controlled trial
15.12.2020To test in a multicenter open-label randomized controlled trial across Switzerland whether a cascade screening programme for FH, in comparison with usual care, will increase the detection rate of FH within families. The primary outcome will be the...
Klinische Forschung - 15.12.2020 - 31.03.2024
Abgeschlossen
Projektleitung: Rickli Hans
Mitarbeiter/innen: Vetsch Susanne, Schneider Irene
SILENT 2
04.12.2020Incidence of Silent Atrial Fibrillation in Patients With Clinically Silent Brain Ischemic Lesions Arterial Fibrillation (AF) is well-recognized as a cause for cryptogenic Acute Ischemic Stroke (AIS) and is associated with Silent Brain Infarction...
Klinische Forschung - 04.12.2020 - 04.12.2024
Laufend
Projektleitung: Ammann Peter, Kägi Georg
Mitarbeiter/innen: Brenner Roman, Vetsch Susanne, Schneider Irene
Smartphone-Enabled Detection of COugh in COvid-19 (COCO): An Exploratory, Single-Center, Observational Cohort Study
03.12.2020
Klinische Forschung - 03.12.2020 - 03.12.2020
Automatisch geschlossen
Projektleitung: Rassouli Frank
Mitarbeiter/innen: Bösch Maximilian, Brutsche Martin, Tinschert Peter, Barata Filipe, Shih Iris
Validation of a textile-based monitoring device for the continuous surveillance of respiratory activity in patients during sedation
01.12.2020
Klinische Forschung - 01.12.2020 - 30.11.2021
Automatisch geschlossen
ASSESS
01.12.2020A randomized, double-blind, placebo-controlled, multi-Center Phase 2 study to assess the efficacy and safety of oral BAY 2327949 in patients with clinical diagnosis of chronic kidney disease due to diabetes or hypertension and at least one cardiovasc...
Klinische Forschung - 01.12.2020 - 31.12.2021
Abgebrochen
Projektleitung: Bilz Stefan
Mitarbeiter/innen: Räss Andrea, Grillmayr Victoria
COMET-T
01.12.2020Nicht-interventionelle, multizentrische, prospektive Studie zur Erfassung der glykämischen Variabilität in Diabetes mellitus Typ 1 Patienten nach Umstellung auf Insulin glargin 300 E/ml (Gla-300) (wegen unzureichender glykämischer Kontrolle) in Kom...
Klinische Forschung - 01.12.2020 - 01.03.2022
Automatisch geschlossen
Projektleitung: Bilz Stefan
Mitarbeiter/innen: Räss Andrea, Grillmayr Victoria
XLH-Register
01.12.2020An international, multicenter, prospective, non-interventional registry for patients with X-linked hypophosphatemia (XLH)
Klinische Forschung - 01.12.2020 - 31.12.2030
Laufend
Projektleitung: Bilz Stefan
Mitarbeiter/innen: Räss Andrea, Grillmayr Victoria
Validation of COVID-19 risk stratification algorithms based on sTREM-1 and IL-6 in Emergency Departments: a retrospective multicenter cohort study
01.12.2020We will retrospectively select SARS-CoV-2 infected adults who attended the ED of St.Gallen and Bellinzona. We want to measure the concentrations from stored blood samples of: Biomarkers of immune dysfunction: e.g., C reactive protein, procalciton...
Klinische Forschung - 01.12.2020 - 28.04.2023
Abgeschlossen
Projektleitung: Albrich Werner
The Role of the Inorganics in Preeclampsia Assessed by Multiscale Characterization of Placentae
01.11.2020
Grundlagenforschung - 01.11.2020 - 30.12.2021
Automatisch geschlossen
Projektleitung: Herrmann Inge
Mitarbeiter/innen: Rduch Thomas, Gogos Alexander, Tsolaki Elena, Leschka Sebastian, Born Diana, Fischer Tina, Hornung René
Development of a non-invasive screening system for the early detection of mild cognitive impairments in older adults
01.11.2020In dem geförderten Kooperationsprojekt “Development of a non-invasive screening system for the early detection of mild cognitive impairments in older adults” wird untersucht, ob ein multimodales nicht-invasives Testsystem geeignet ist, um frühe Stadi...
Klinische Forschung - 01.11.2020 - 01.07.2021
Automatisch geschlossen
Projektleitung: Felbecker Ansgar
Mitarbeiter/innen: Schneider Thomas
IFX-1-P2.5
01.11.2020a randomized, double-blind, double-dummy, active-controlled, multicenter, 2-part Phase 2 study on replacement of steroids by IFX-1 in active granulomatosis with polyangiitis (GPA) and microscopic polyangitis (MPA)
Klinische Forschung - 01.11.2020 - 01.11.2021
Abgeschlossen
Projektleitung: Neumann Thomas
Mitarbeiter/innen: Peischl Riana, Rubbert-Roth Andrea
BMS CA209-914 (Checkmate 914)A Phase 3 Randomized, Double-Blind Study of Nivolumab Monotherapy
29.10.2020The current standard treatment for early stage (l-lll) renal cell cancer (RCC) is surgery. While the prognosis of stage I tumors is excellent, stage II and particularly stage III have a high risk of relapse and represent a high unmet medical need. Th...
Klinische Forschung - 29.10.2020 - 30.09.2030
Laufend
Projektleitung: Rothermundt Christian