Prof. Dr. med. Wolfram Jochum
Chefarzt/Chefärztin
Pathologie · Dept. IV
Status quo of ALK testing in lung cancer: results of an EQA scheme based on in-situ hybridization, immunohistochemistry, and RNA/DNA sequencing
Jurmeister P, Büttner R, Merkelbach-Bruse S, Kreipe H, Jonigk D, Jochum W, Rodriguez R, Dietel M, Horst D, Hummel M, Kirchner T, Neumann J, Vollbrecht C, Jöhrens K, Aust D, Behnke A, Stenzinger A, Penzel R, Endris V, Schirmacher P, Fisseler-Eckhoff A, von Laffert M. Status quo of ALK testing in lung cancer: results of an EQA scheme based on in-situ hybridization, immunohistochemistry, and RNA/DNA sequencing. Virchows Arch 2021; 479:247-255.
25.06.2021Status quo of ALK testing in lung cancer: results of an EQA scheme based on in-situ hybridization, immunohistochemistry, and RNA/DNA sequencing
25.06.2021Virchows Arch 2021; 479:247-255
Jurmeister Philipp, Büttner Reinhard, Merkelbach-Bruse Sabine, Kreipe Hans, Jonigk Danny, Jochum Wolfram, Rodriguez Regulo, Dietel Manfred, Horst David, Hummel Michael, Kirchner Thomas, Neumann Jens, Vollbrecht Claudia, Jöhrens Korinna, Aust Daniela, Behnke Anke, Stenzinger Albrecht, Penzel Roland, Endris Volker, Schirmacher Peter, Fisseler-Eckhoff Annette, von Laffert Maximilian
Differential Diagnosis of Central Neurocytoma: Two Cases
Steinsiepe V, Frick H, Jochum W, Fournier J. Differential Diagnosis of Central Neurocytoma: Two Cases. J Neurol Surg A Cent Eur Neurosurg 2020
22.12.2020Differential Diagnosis of Central Neurocytoma: Two Cases
22.12.2020J Neurol Surg A Cent Eur Neurosurg 2020
Steinsiepe V K, Frick H, Jochum Wolfram, Fournier J Y
Genomic profiling of late-onset basal cell carcinomas from two brothers with nevoid basal cell carcinoma syndrome
Hasan Ali O, Navarini A, Kim A, French L, Dermitzakis E, Christiano A, Hohl D, Bickers D, Nikolaev S, Jochum W, Fritzsche F, Yurchenko A, Pavlova O, Sartori A, Bomze D, Higgins R, Ring S, Hartmann F, Bühler D, Flatz L. Genomic profiling of late-onset basal cell carcinomas from two brothers with nevoid basal cell carcinoma syndrome. J Eur Acad Dermatol Venereol 2020
21.06.2020Genomic profiling of late-onset basal cell carcinomas from two brothers with nevoid basal cell carcinoma syndrome
21.06.2020J Eur Acad Dermatol Venereol 2020
Hasan Ali O, Navarini A A, Kim A, French L E, Dermitzakis E, Christiano A M, Hohl D, Bickers D R, Nikolaev S I, Jochum Wolfram, Fritzsche F R, Yurchenko A A, Pavlova O, Sartori A, Bomze D, Higgins R, Ring Sandra, Hartmann F, Bühler D, Flatz Lukas
Outcomes with immune checkpoint inhibitors for relapsed small-cell lung cancer in a Swiss cohort
Schmid S, Jochum W, Addeo A, Demmer I, Schär S, Janthur W, Wannesson L, König D, Britschgi C, Frösch P, Bouchaab H, Rothschild S, Blum V, Friedlaender A, Mauti L, Früh M. Outcomes with immune checkpoint inhibitors for relapsed small-cell lung cancer in a Swiss cohort. Cancer Immunol Immunother 2020; 69:1605-1613.
19.04.2020Outcomes with immune checkpoint inhibitors for relapsed small-cell lung cancer in a Swiss cohort
19.04.2020Cancer Immunol Immunother 2020; 69:1605-1613
Schmid Sabine, Jochum Wolfram, Addeo Alfredo, Demmer Izadora, Schär Sämi, Janthur Wolf-Dieter, Wannesson Luciano, König David, Britschgi Christian, Frösch Patrizia, Bouchaab Hasna, Rothschild Sacha I, Blum Veronika, Friedlaender Alex, Mauti Laetitia A, Früh Martin
Do YOU know the Ki-67 index of your breast cancer patients? Knowledge of your institution's Ki-67 index distribution and its robustness is essential for decision-making in early breast cancer
Maranta A, Broder S, Fritzsche C, Knauer M, Thürlimann B, Jochum W, Ruhstaller T. Do YOU know the Ki-67 index of your breast cancer patients? Knowledge of your institution's Ki-67 index distribution and its robustness is essential for decision-making in early breast cancer. Breast 2020; 51:120-126.
23.03.2020Do YOU know the Ki-67 index of your breast cancer patients? Knowledge of your institution's Ki-67 index distribution and its robustness is essential for decision-making in early breast cancer
23.03.2020Breast 2020; 51:120-126
Maranta Angela Fischer, Broder Simon, Fritzsche Constanze, Knauer Michael, Thürlimann Beat, Jochum Wolfram, Ruhstaller Thomas
Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure
Anthis A, Chavatte-Palmer P, Jochum W, Wick P, Dommann A, Bürki-Turnherr T, Fischer T, Hornung R, Bertazzo S, Lehner S, Wildermuth S, Leschka S, Tsolaki E, Didierlaurent L, Staubli S, Zboray R, Neels A, Dietrich D, Manser P, Desbiolles L, Herrmann I. Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure. Analyst 2019; 144:6850-6857.
18.11.2019Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure
18.11.2019Analyst 2019; 144:6850-6857
Anthis Alexandre H C, Chavatte-Palmer Pascale, Jochum Wolfram, Wick Peter, Dommann Alex, Bürki-Turnherr Tina, Fischer Tina, Hornung René, Bertazzo Sergio, Lehner Sandro, Wildermuth Simon, Leschka Sebastian, Tsolaki Elena, Didierlaurent Louis, Staubli Samuel, Zboray Robert, Neels Antonia, Dietrich Dörthe, Manser Pius, Desbiolles Lotus May, Herrmann Inge K
Ki-67 assessment in early breast cancer: SAKK28/12 validation study on the IBCSG VIII and IBCSG IX cohort
Varga Z, Thürlimann B, Klingbiel D, Hawle H, Tille J, Rau T, Perriard U, Jochum W, Li Q, Ruhstaller T. Ki-67 assessment in early breast cancer: SAKK28/12 validation study on the IBCSG VIII and IBCSG IX cohort. Sci Rep 2019; 9:13534.
19.09.2019Ki-67 assessment in early breast cancer: SAKK28/12 validation study on the IBCSG VIII and IBCSG IX cohort
19.09.2019Sci Rep 2019; 9:13534
Varga Zsuzsanna, Thürlimann Beat, Klingbiel Dirk, Hawle Hanne, Tille Jean-Christoph, Rau Tilman, Perriard Ulrike, Jochum Wolfram, Li Qiyu, Ruhstaller Thomas
High-throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification
Zhu Y, Christiansen A, Fritz C, Rupp N, Poyet C, Rushing E, Weller M, Roth P, Haralambieva E, Hofer S, Chen C, Jochum W, Gao X, Teng X, Chen L, Zhong Q, Wild P, Aebersold R, Ljubicic J, Rutishauser D, Schmid M, Weiss T, Zhang Q, Sun R, Wang B, Yi X, Wu Z, Gao H, Cai X, Ruan G, Zhu T, Xu C, Lou S, Yu X, Gillet L, Blattmann P, Saba K, Fankhauser C, Guo T. High-throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification. Mol Oncol 2019; 13:2305-2328.
18.09.2019High-throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification
18.09.2019Mol Oncol 2019; 13:2305-2328
Zhu Yi, Christiansen Ailsa, Fritz Christine, Rupp Niels J, Poyet Cédric, Rushing Elisabeth, Weller Michael, Roth Patrick, Haralambieva Eugenia, Hofer Silvia, Chen Chen, Jochum Wolfram, Gao Xiaofei, Teng Xiaodong, Chen Lirong, Zhong Qing, Wild Peter J, Aebersold Ruedi, Ljubicic Jelena, Rutishauser Dorothea, Schmid Michael, Weiss Tobias, Zhang Qiushi, Sun Rui, Wang Bo, Yi Xiao, Wu Zhicheng, Gao Huanhuan, Cai Xue, Ruan Guan, Zhu Tiansheng, Xu Chao, Lou Sai, Yu Xiaoyan, Gillet Ludovic, Blattmann Peter, Saba Karim, Fankhauser Christian D, Guo Tiannan
BP180-specific IgG is associated with skin adverse events, therapy response, and overall survival in non-small cell lung cancer patients treated with checkpoint inhibitors
Hasan Ali O, Sadik C, Zillikens D, Schmidt E, Jochum W, Mani B, Cozzio A, Braun A, Emtenani S, Hammers C, Abdou M, Diem S, Fässler M, Berner F, Ring S, Bomze D, Flatz L. BP180-specific IgG is associated with skin adverse events, therapy response, and overall survival in non-small cell lung cancer patients treated with checkpoint inhibitors. J Am Acad Dermatol 2019; 82:854-861.
23.08.2019BP180-specific IgG is associated with skin adverse events, therapy response, and overall survival in non-small cell lung cancer patients treated with checkpoint inhibitors
23.08.2019J Am Acad Dermatol 2019; 82:854-861
Hasan Ali Omar, Sadik Christian D, Zillikens Detlef, Schmidt Enno, Jochum Wolfram, Mani Bernhard, Cozzio Antonio, Braun Anne, Emtenani Shirin, Hammers Christoph, Abdou Marie-Therese, Diem Stefan, Fässler Mirjam, Berner Fiamma, Ring Sandra S, Bomze David, Flatz Lukas
Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer
Berner F, Hartmann F, Cheng H, Hönger G, Recher M, Goldman J, Cozzio A, Früh M, Neefjes J, Driessen C, Ludewig B, Hegazy A, Jochum W, Speiser D, Zippelius A, Läubli H, Bomze D, Diem S, Ali O, Fässler M, Ring S, Niederer R, Ackermann C, Baumgaertner P, Pikor N, Cruz C, van de Veen W, Akdis M, Nikolaev S, Flatz L. Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer. JAMA Oncol 2019; 5:1043-1047.
01.07.2019Association of Checkpoint Inhibitor-Induced Toxic Effects With Shared Cancer and Tissue Antigens in Non-Small Cell Lung Cancer
01.07.2019JAMA Oncol 2019; 5:1043-1047
Berner Fiamma, Hartmann Fabienne, Cheng Hung-Wei, Hönger Gideon, Recher Mike, Goldman Jonathan, Cozzio Antonio, Früh Martin, Neefjes Jacques, Driessen Christoph, Ludewig Burkhard, Hegazy Ahmed N, Jochum Wolfram, Speiser Daniel E, Zippelius Alfred, Läubli Heinz, Bomze David, Diem Stefan, Ali Omar Hasan, Fässler Mirjam, Ring Sandra, Niederer Rebekka, Ackermann Christoph J, Baumgaertner Petra, Pikor Natalia, Cruz Cristina Gil, van de Veen Willem, Akdis Mübeccel, Nikolaev Sergey, Flatz Lukas
PD-L1 testing of non-small cell lung cancer using different antibodies and platforms: a Swiss cross-validation study
Savic S, Soltermann A, Zweifel R, Zettl A, von Gunten M, Singer G, Rössle M, Jasarevic Z, Letovanec I, McKee T, Komminoth P, Jochum W, Fleischmann A, Diebold J, Cathomas G, Eppenberger-Castori S, Berezowska S, Bubendorf L. PD-L1 testing of non-small cell lung cancer using different antibodies and platforms: a Swiss cross-validation study. Virchows Arch 2019; 475:67-76.
24.05.2019PD-L1 testing of non-small cell lung cancer using different antibodies and platforms: a Swiss cross-validation study
24.05.2019Virchows Arch 2019; 475:67-76
Savic Spasenija, Soltermann Alex, Zweifel Roland, Zettl Andreas, von Gunten Michael, Singer Gad, Rössle Matthias, Jasarevic Zerina, Letovanec Igor, McKee Thomas, Komminoth Paul, Jochum Wolfram, Fleischmann Achim, Diebold Joachim, Cathomas Gieri, Eppenberger-Castori Serenella, Berezowska Sabina, Bubendorf Lukas
Controlled attenuation parameter for the assessment of liver steatosis in comparison with liver histology: a single-centre real life experience
Baumeler S, Jochum W, Neuweiler J, Bergamin I, Semela D. Controlled attenuation parameter for the assessment of liver steatosis in comparison with liver histology: a single-centre real life experience. Swiss Med Wkly 2019; 149:w20077.
26.04.2019Controlled attenuation parameter for the assessment of liver steatosis in comparison with liver histology: a single-centre real life experience
26.04.2019Swiss Med Wkly 2019; 149:w20077
Baumeler Stephan, Jochum Wolfram, Neuweiler Jörg, Bergamin Irina, Semela David
Patterns of progression on osimertinib in EGFR T790M positive NSCLC: A Swiss cohort study
Schmid S, Jochum W, Demmer I, Foerbs D, Janthur W, Wannesson L, Rothschild S, Pless M, Gautschi O, Britschgi C, Aeppli S, Klingbiel D, Früh M. Patterns of progression on osimertinib in EGFR T790M positive NSCLC: A Swiss cohort study. Lung Cancer 2019; 130:149-155.
19.02.2019Patterns of progression on osimertinib in EGFR T790M positive NSCLC: A Swiss cohort study
19.02.2019Lung Cancer 2019; 130:149-155
Schmid Sabine, Jochum Wolfram, Demmer I, Foerbs D, Janthur W, Wannesson L, Rothschild S, Pless M, Gautschi O, Britschgi C, Aeppli Stefanie, Klingbiel D, Früh Martin
Cost-Efficient and Easy to Perform PCR-Based Assay to Identify Met Exon 14 Skipping in Formalin-Fixed Paraffin-Embedded (FFPE) Non-Small Cell Lung Cancer (NSCLC) Samples
O'Brien O, Gray S, Jörger M, Jochum W, Fabre A, Cuffe S, Nicholson S, Leonard N, Geoghegan O, O'Brien C, Wright M, Finn S. Cost-Efficient and Easy to Perform PCR-Based Assay to Identify Met Exon 14 Skipping in Formalin-Fixed Paraffin-Embedded (FFPE) Non-Small Cell Lung Cancer (NSCLC) Samples. Diagnostics (Basel) 2019; 9
18.01.2019Cost-Efficient and Easy to Perform PCR-Based Assay to Identify Met Exon 14 Skipping in Formalin-Fixed Paraffin-Embedded (FFPE) Non-Small Cell Lung Cancer (NSCLC) Samples
18.01.2019Diagnostics (Basel) 2019; 9
O'Brien Odharnaith, Gray Steven G, Jörger Markus, Jochum Wolfram, Fabre Aurelie, Cuffe Sinead, Nicholson Siobhan, Leonard Niamh, Geoghegan Orla, O'Brien Cathal, Wright Mark C, Finn Stephen P
Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma.
Plath M, Broglie M, Förbs D, Stoeckli S, Jochum W. Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma. J Otolaryngol Head Neck Surg 2018; 47:53.
06.09.2018Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma.
06.09.2018J Otolaryngol Head Neck Surg 2018; 47:53
Plath Michaela, Broglie Martina A, Förbs Diana, Stoeckli Sandro J, Jochum Wolfram
Endoscopic Treatment of Early Barrett's Adenocarcinoma and Dysplasia: Focus on Submucosal Cancer
Frei N, Frei R, Semadeni G, Jochum W, Brand S, Borovicka J. Endoscopic Treatment of Early Barrett's Adenocarcinoma and Dysplasia: Focus on Submucosal Cancer. Digestion 2018; 99:293-300.
03.09.2018Endoscopic Treatment of Early Barrett's Adenocarcinoma and Dysplasia: Focus on Submucosal Cancer
03.09.2018Digestion 2018; 99:293-300
Frei Nicola Fabian, Frei Remus, Semadeni Gian-Marco, Jochum Wolfram, Brand Stephan, Borovicka Jan
[Treatment of Advanced Prostate Carcinoma - an Interdisciplinary Recommendation]
Omlin A, Zwahlen D, Wyler S, Wild D, Templeton A, Stenner F, Schmid H, Roggero E, Rentsch C, Nitzsche E, Kueng M, Jochum W, Gillessen Sommer S, Eberli D, Beyer J, Spahn M, Cathomas R. [Treatment of Advanced Prostate Carcinoma - an Interdisciplinary Recommendation]. Praxis (Bern 1994) 2018; 107:1043-1051.
01.09.2018[Treatment of Advanced Prostate Carcinoma - an Interdisciplinary Recommendation]
01.09.2018Praxis (Bern 1994) 2018; 107:1043-1051
Omlin Aurelius, Zwahlen Daniel, Wyler Stephen, Wild Damian, Templeton Arnoud J, Stenner Frank, Schmid Hans-Peter, Roggero Enrico, Rentsch Cyrill A, Nitzsche Egbert, Kueng Marc, Jochum Wolfram, Gillessen Sommer Silke, Eberli Daniel, Beyer Jörg, Spahn Martin, Cathomas Richard
Organ-specific response to nivolumab in patients with non-small cell lung cancer (NSCLC)
Schmid S, Jochum W, Klingbiel D, Desbiolles L, Leschka S, Flatz L, Krapf M, Li Q, Diem S, Früh M. Organ-specific response to nivolumab in patients with non-small cell lung cancer (NSCLC). Cancer Immunol Immunother 2018
31.08.2018Organ-specific response to nivolumab in patients with non-small cell lung cancer (NSCLC)
31.08.2018Cancer Immunol Immunother 2018
Schmid Sabine, Jochum Wolfram, Klingbiel Dirk, Desbiolles Lotus, Leschka Sebastian, Flatz Lukas, Krapf Mirjam, Li Qiyu, Diem Stefan, Früh Martin
The prognostic value of signet ring cell histology in stage I/II colon cancer-a population-based, propensity score-matched analysis
Ackermann C, Gueller U, Jochum W, Schmied B, Warschkow R. The prognostic value of signet ring cell histology in stage I/II colon cancer-a population-based, propensity score-matched analysis. Int J Colorectal Dis 2018
07.06.2018The prognostic value of signet ring cell histology in stage I/II colon cancer-a population-based, propensity score-matched analysis
07.06.2018Int J Colorectal Dis 2018
Ackermann Christoph Jakob, Gueller Ulrich, Jochum Wolfram, Schmied Bruno, Warschkow Rene
Multi-region proteome analysis quantifies spatial heterogeneity of prostate tissue biomarkers
Guo T, Aebersold R, Wild P, Poyet C, Saba K, Fankhauser C, Jochum W, Rueschoff J, Wagner U, Wong C, Charmpi K, Rupp N, Zhong Q, Li L, Beyer A. Multi-region proteome analysis quantifies spatial heterogeneity of prostate tissue biomarkers. Life Sci Alliance 2018; 1
29.05.2018Multi-region proteome analysis quantifies spatial heterogeneity of prostate tissue biomarkers
29.05.2018Life Sci Alliance 2018; 1
Guo Tiannan, Aebersold Ruedi, Wild Peter J, Poyet Cédric, Saba Karim, Fankhauser Christian Daniel, Jochum Wolfram, Rueschoff Jan H, Wagner Ulrich, Wong Christine E, Charmpi Konstantina, Rupp Niels J, Zhong Qing, Li Li, Beyer Andreas