Prof. Dr. med. Wolfram Jochum
Chefarzt/Chefärztin
Pathologie · Dept. IV
Reproducible Tissue Homogenization and Protein Extraction for Quantitative Proteomics Using MicroPestle-Assisted Pressure-Cycling Technology
Shao S, Guo T, Gross V, Lazarev A, Koh C, Gillessen Sommer S, Jörger M, Jochum W, Aebersold R. Reproducible Tissue Homogenization and Protein Extraction for Quantitative Proteomics Using MicroPestle-Assisted Pressure-Cycling Technology. J Proteome Res 2016; 15:1821-9.
10.05.2016Reproducible Tissue Homogenization and Protein Extraction for Quantitative Proteomics Using MicroPestle-Assisted Pressure-Cycling Technology
10.05.2016J Proteome Res 2016; 15:1821-9
Shao Shiying, Guo Tiannan, Gross Vera, Lazarev Alexander, Koh Ching Chiek, Gillessen Sommer Silke, Jörger Markus, Jochum Wolfram, Aebersold Ruedi
Image-based computational quantification and visualization of genetic alterations and tumour heterogeneity
Zhong Q, Poyet C, Blattner M, Soldini D, Moch H, Rubin M, Noske A, Rüschoff J, Haffner M, Jochum W, Perner S, Buhmann J, Rüschoff J, Guo T, Gabrani M, Schüffler P, Rechsteiner M, Liu Y, Fuchs T, Rupp N, Fankhauser C, Wild P. Image-based computational quantification and visualization of genetic alterations and tumour heterogeneity. Sci Rep 2016; 6:24146.
07.04.2016Image-based computational quantification and visualization of genetic alterations and tumour heterogeneity
07.04.2016Sci Rep 2016; 6:24146
Zhong Qing, Poyet Cédric, Blattner Miriam, Soldini Davide, Moch Holger, Rubin Mark A, Noske Aurelia, Rüschoff Josef, Haffner Michael C, Jochum Wolfram, Perner Sven, Buhmann Joachim M, Rüschoff Jan H, Guo Tiannan, Gabrani Maria, Schüffler Peter J, Rechsteiner Markus, Liu Yansheng, Fuchs Thomas J, Rupp Niels J, Fankhauser Christian, Wild Peter J
NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusions of the first international round robin trial
Endris V, Weichert W, Dietel M, Höfler G, Jochum W, Büttner R, Kirchner T, Kreipe H, Lehmann U, Jung A, Sabine-Merkelbach-Bruse, Hummel M, Darb-Esfahani S, Lenze D, Möbs M, Penzel R, Pfarr N, Stenzinger A, Schirmacher P. NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusions of the first international round robin trial. Virchows Arch 2016; 468:697-705.
22.03.2016NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusions of the first international round robin trial
22.03.2016Virchows Arch 2016; 468:697-705
Endris Volker, Weichert Wilko, Dietel Manfred, Höfler Gerald, Jochum Wolfram, Büttner Reinhard, Kirchner Thomas, Kreipe Hans, Lehmann Ulrich, Jung Andreas, Sabine-Merkelbach-Bruse, Hummel Michael, Darb-Esfahani Silvia, Lenze Dido, Möbs Markus, Penzel Roland, Pfarr Nicole, Stenzinger Albrecht, Schirmacher Peter
Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy
Schmid P, Weber R, Opravil M, Vernazza P, Mullhaupt B, Jochum W, Rauch A, Huber M, Bregenzer A, Swiss HIV Cohort Study. Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy. PloS one 2015; 10:e0138838.
29.09.2015Progression of Liver Fibrosis in HIV/HCV Co-Infection: A Comparison between Non-Invasive Assessment Methods and Liver Biopsy
29.09.2015PloS one 2015; 10:e0138838
Schmid Patrick, Weber Rainer, Opravil Milos, Vernazza Pietro, Mullhaupt Beat, Jochum Wolfram, Rauch Andri, Huber Milo, Bregenzer Andrea, Swiss HIV Cohort Study
Minimal sample requirement for highly multiplexed protein quantification in cell lines and tissues by PCT-SWATH mass spectrometry
Shao S, Guo T, Koh C, Gillessen Sommer S, Jörger M, Jochum W, Aebersold R. Minimal sample requirement for highly multiplexed protein quantification in cell lines and tissues by PCT-SWATH mass spectrometry. Proteomics 2015; 15:3711-21.
10.09.2015Minimal sample requirement for highly multiplexed protein quantification in cell lines and tissues by PCT-SWATH mass spectrometry
10.09.2015Proteomics 2015; 15:3711-21
Shao Shiying, Guo Tiannan, Koh Chiek Ching, Gillessen Sommer Silke, Jörger Markus, Jochum Wolfram, Aebersold Ruedi
Brush cytology for the detection of high-risk HPV infection in oropharyngeal squamous cell carcinoma
Broglie Däppen M, Jochum W, Förbs D, Schönegg R, Stöckli S. Brush cytology for the detection of high-risk HPV infection in oropharyngeal squamous cell carcinoma. Cancer Cytopathol 2015; 123:732-8.
08.09.2015Brush cytology for the detection of high-risk HPV infection in oropharyngeal squamous cell carcinoma
08.09.2015Cancer Cytopathol 2015; 123:732-8
Broglie Däppen Martina, Jochum Wolfram, Förbs Diana, Schönegg René, Stöckli Sandro
Brain metastases in gastro-oesophageal adenocarcinoma: insights into the role of the human epidermal growth factor receptor 2 (HER2)
Feilchenfeldt J, Jochum W, Shoji H, Kushima R, Wagner D, Shimada Y, Cats A, Knuth A, Moch H, Aebi S, Diebold J, Khanfir K, Varga Z, Siano M, Grabsch H, Held U, Schuknecht B, Trip A, Hamaguchi T, Gut P, Balague O, Hofer S. Brain metastases in gastro-oesophageal adenocarcinoma: insights into the role of the human epidermal growth factor receptor 2 (HER2). Br J Cancer 2015; 113:716-21.
27.08.2015Brain metastases in gastro-oesophageal adenocarcinoma: insights into the role of the human epidermal growth factor receptor 2 (HER2)
27.08.2015Br J Cancer 2015; 113:716-21
Feilchenfeldt J, Jochum Wolfram, Shoji H, Kushima R, Wagner D, Shimada Y, Cats A, Knuth A, Moch H, Aebi S, Diebold J, Khanfir K, Varga Z, Siano Marco, Grabsch H I, Held U, Schuknecht B, Trip A, Hamaguchi T, Gut P, Balague O, Hofer S
Screening for ALK in non-small cell lung carcinomas: 5A4 and D5F3 antibodies perform equally well, but combined use with FISH is recommended
Savic S, Kerr K, Bisig B, Tornillo L, Grieshaber S, Baschiera B, Jochum W, Zimmermann A, Diebold J, Bubendorf L. Screening for ALK in non-small cell lung carcinomas: 5A4 and D5F3 antibodies perform equally well, but combined use with FISH is recommended. Lung Cancer 2015; 89:104-9.
21.05.2015Screening for ALK in non-small cell lung carcinomas: 5A4 and D5F3 antibodies perform equally well, but combined use with FISH is recommended
21.05.2015Lung Cancer 2015; 89:104-9
Savic Spasenija, Kerr Keith, Bisig Bettina, Tornillo Luigi, Grieshaber Susanne, Baschiera Betty, Jochum Wolfram, Zimmermann Anne-Katrin, Diebold Joachim, Bubendorf Lukas
Bidirectional Transfer Study of Polystyrene Nanoparticles across the Placental Barrier in an ex Vivo Human Placental Perfusion Model
Grafmueller S, von Mandach U, Buerki-Thurnherr T, Krug H, Jochum W, Maurizi L, Maeder-Althaus X, Diener P, Diener L, Manser P, Wick P. Bidirectional Transfer Study of Polystyrene Nanoparticles across the Placental Barrier in an ex Vivo Human Placental Perfusion Model. Environ Health Perspect 2015; 123:1280-6.
08.05.2015Bidirectional Transfer Study of Polystyrene Nanoparticles across the Placental Barrier in an ex Vivo Human Placental Perfusion Model
08.05.2015Environ Health Perspect 2015; 123:1280-6
Grafmueller Stefanie, von Mandach Ursula, Buerki-Thurnherr Tina, Krug Harald F, Jochum Wolfram, Maurizi Lionel, Maeder-Althaus Xenia, Diener Pierre-André, Diener Liliane, Manser Pius, Wick Peter
In welchem Zusammenhang stehen quälende Beinschmerzen und eine intrauterine Spirale?
Jäckel K, Braschler T, Jochum W, Hülder T, Knechtle B. In welchem Zusammenhang stehen quälende Beinschmerzen und eine intrauterine Spirale?. Praxis Schweizerische Rundschau für Medizin 2015; 104:517-522.
06.05.2015In welchem Zusammenhang stehen quälende Beinschmerzen und eine intrauterine Spirale?
06.05.2015Praxis Schweizerische Rundschau für Medizin 2015; 104:517-522
Jäckel Kristian, Braschler Thomas, Jochum Wolfram, Hülder Tanja, Knechtle Beat
Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps
Guo T, Jochum W, Jörger M, Gillessen Sommer S, Blum L, Collins B, Rosenberger G, Röst H, Wolski W, Gillet L, Koh C, Kouvonen P, Aebersold R. Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps. Nat Med 2015; 21:407-13.
02.03.2015Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps
02.03.2015Nat Med 2015; 21:407-13
Guo Tiannan, Jochum Wolfram, Jörger Markus, Gillessen Sommer Silke, Blum Lorenz C, Collins Ben C, Rosenberger George, Röst Hannes L, Wolski Witold E, Gillet Ludovic C, Koh Ching Chiek, Kouvonen Petri, Aebersold Ruedi
Impact of clinical risk scores and BRAF V600E mutation status on outcome in papillary thyroid cancer
Niederer-Wuest S, Stöckli S, ess s, Haile S, Müller J, Oettli R, Clerici T, Bilz S, Brändle M, Förbs D, Jochum W, Broglie Däppen M. Impact of clinical risk scores and BRAF V600E mutation status on outcome in papillary thyroid cancer. Surgery 2015; 157:119-25.
01.01.2015Impact of clinical risk scores and BRAF V600E mutation status on outcome in papillary thyroid cancer
01.01.2015Surgery 2015; 157:119-25
Niederer-Wuest Severine, Stöckli Sandro, ess silvia, Haile Sarah, Müller Joachim, Oettli Rene, Clerici Thomas, Bilz Stefan, Brändle Michael, Förbs Diana, Jochum Wolfram, Broglie Däppen Martina
Histopathological mapping of metastatic tumor cells in sentinel lymph nodes of oral and oropharyngeal squamous cell carcinomas
Denoth S, Broglie Däppen M, Haerle S, Huber G, Haile S, Soltermann A, Jochum W, Stöckli S. Histopathological mapping of metastatic tumor cells in sentinel lymph nodes of oral and oropharyngeal squamous cell carcinomas. Head & neck 2014
02.06.2014Histopathological mapping of metastatic tumor cells in sentinel lymph nodes of oral and oropharyngeal squamous cell carcinomas
02.06.2014Head & neck 2014
Denoth Seraina, Broglie Däppen Martina, Haerle Stephan K, Huber Gerhard F, Haile Sarah, Soltermann Alex, Jochum Wolfram, Stöckli Sandro
EGFR expression and copy number changes in low T-stage oral squamous cell carcinomas
Rössle M, Weber C, Züllig L, Jochum W, Stöckli S, Moch H, Huber G. EGFR expression and copy number changes in low T-stage oral squamous cell carcinomas. Histopathology 2013; 63:271-8.
13.06.2013EGFR expression and copy number changes in low T-stage oral squamous cell carcinomas
13.06.2013Histopathology 2013; 63:271-8
Rössle Matthias, Weber Claudia S, Züllig Lena, Jochum Wolfram, Stöckli Sandro, Moch Holger, Huber Gerhard F
Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): results of a multi-centre ALK-testing
V Laffert M, Wölfel C, Petersen I, Rodriguez R, Jochum W, Bartsch H, Fisseler-Eckhoff A, Berg E, Lenze D, Dietel M, Kirchner T, Jung A, Kerler R, Warth A, Penzel R, Schirmacher P, Jonigk D, Kreipe H, Schildhaus H, Merkelbach-Bruse S, Büttner R, Reu S, Hummel M. Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): results of a multi-centre ALK-testing. Lung Cancer 2013; 81:200-6.
10.05.2013Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): results of a multi-centre ALK-testing
10.05.2013Lung Cancer 2013; 81:200-6
V Laffert Maximilian, Wölfel Cornelius, Petersen Iver, Rodriguez Regulo, Jochum Wolfram, Bartsch Holger, Fisseler-Eckhoff Annette, Berg Erika, Lenze Dido, Dietel Manfred, Kirchner Thomas, Jung Andreas, Kerler Rosi, Warth Arne, Penzel Roland, Schirmacher Peter, Jonigk Danny, Kreipe Hans, Schildhaus Hans-Ulrich, Merkelbach-Bruse Sabine, Büttner Reinhard, Reu Simone, Hummel Michael
Comparison of automated and manual FISH for evaluation of HER2 gene status on breast carcinoma core biopsies
Öhlschlegel C, Kradolfer D, Hell M, Jochum W. Comparison of automated and manual FISH for evaluation of HER2 gene status on breast carcinoma core biopsies. BMC Clin Pathol 2013; 13:13.
20.04.2013Comparison of automated and manual FISH for evaluation of HER2 gene status on breast carcinoma core biopsies
20.04.2013BMC Clin Pathol 2013; 13:13
Öhlschlegel Christian, Kradolfer Doris, Hell Margreth, Jochum Wolfram
Reproducibility of Immunohistochemical Scoring for Epidermal Growth Factor Receptor Expression in Non-Small Cell Lung Cancer
Rüschoff J, López-Ríos F, Marx A, Molina T, Olszewski W, Rieker R, Volante M, Thunnissen E, Wrba F, Celik I, Lo A, Jochum W, Kerr K, Grote H, Middel P, von Heydebreck A, Alves V, Baldus S, Büttner R, Carvalho L, Fink L, Störkel S. Reproducibility of Immunohistochemical Scoring for Epidermal Growth Factor Receptor Expression in Non-Small Cell Lung Cancer. Arch Pathol Lab Med 2012
27.12.2012Reproducibility of Immunohistochemical Scoring for Epidermal Growth Factor Receptor Expression in Non-Small Cell Lung Cancer
27.12.2012Arch Pathol Lab Med 2012
Rüschoff Josef, López-Ríos Fernando, Marx Alexander, Molina Thierry J, Olszewski Włodzimierz T, Rieker Ralf J, Volante Marco, Thunnissen Erik, Wrba Fritz, Celik Ilhan, Lo Anthony W I, Jochum Wolfram, Kerr Keith M, Grote Hans J, Middel Peter, von Heydebreck Anja, Alves Venâncio A, Baldus Stephan E, Büttner Reinhard, Carvalho Lina, Fink Ludger, Störkel Stephan
Quantification of coronary artery stenosis with high-resolution CT in comparison with histopathology in an ex vivo study
Dettmer M, Wildermuth S, Alkadhi H, Jochum W, Feuchtner G, Fornaro J, Glaser-Gallion F, Stolzmann P, Glaser-Gallion N, Leschka S. Quantification of coronary artery stenosis with high-resolution CT in comparison with histopathology in an ex vivo study. Eur J Radiol 2012; 82:264-9.
29.10.2012Quantification of coronary artery stenosis with high-resolution CT in comparison with histopathology in an ex vivo study
29.10.2012Eur J Radiol 2012; 82:264-9
Dettmer Matthias, Wildermuth Simon, Alkadhi Hatem, Jochum Wolfram, Feuchtner Gudrun, Fornaro Jürgen, Glaser-Gallion Florian, Stolzmann Paul, Glaser-Gallion Nicola, Leschka Sebastian
Carcinoma of the collecting ducts of Bellini and renal medullary carcinoma: clinicopathologic analysis of 52 cases of rare aggressive subtypes of renal cell carcinoma with a focus on their interrelationship
Gupta R, Gown A, Cabrera R, Salles P, Vankalakunti M, Zhou M, Hansel D, de Castro M, Bacchi C, Hes O, Jochum W, Osunkoya A, Moch H, Shah R, Billis A, Amin M. Carcinoma of the collecting ducts of Bellini and renal medullary carcinoma: clinicopathologic analysis of 52 cases of rare aggressive subtypes of renal cell carcinoma with a focus on their interrelationship. Am J Surg Pathol 2012; 36:1265-78.
01.09.2012Carcinoma of the collecting ducts of Bellini and renal medullary carcinoma: clinicopathologic analysis of 52 cases of rare aggressive subtypes of renal cell carcinoma with a focus on their interrelationship
01.09.2012Am J Surg Pathol 2012; 36:1265-78
Gupta Ruta, Gown Allen M, Cabrera Rafael A, Salles Paulo G, Vankalakunti Mahesha, Zhou Ming, Hansel Donna E, de Castro Marilia G, Bacchi Carlos E, Hes Ondrej, Jochum Wolfram, Osunkoya Adeboye O, Moch Holger, Shah Rajal B, Billis Athanase, Amin Mahul B
Ribosomal protein l13a as a reference gene for human bone marrow-derived mesenchymal stromal cells during expansion, adipo-, chondro-, and osteogenesis
Studer D, Lischer S, Jochum W, Ehrbar M, Zenobi-Wong M, Maniura-Weber K. Ribosomal protein l13a as a reference gene for human bone marrow-derived mesenchymal stromal cells during expansion, adipo-, chondro-, and osteogenesis. Tissue Eng Part C Methods 2012; 18:761-71.
07.06.2012Ribosomal protein l13a as a reference gene for human bone marrow-derived mesenchymal stromal cells during expansion, adipo-, chondro-, and osteogenesis
07.06.2012Tissue Eng Part C Methods 2012; 18:761-71
Studer Deborah, Lischer Stefanie, Jochum Wolfram, Ehrbar Martin, Zenobi-Wong Marcy, Maniura-Weber Katharina