The present project has several objectives. Our main goal is to evaluate the hemodynamic characteristics in particular the mean pulmonary artery wedge pressure (mPAWP) of patients with versus without bendopnea and those with high (supramedian) vers...

Klinische Forschung - 01.07.2024 - 30.06.2026

Laufend

Projektleitung: Maeder Micha
Mitarbeiter/innen: Schneider Irene

To evaluate the continued safety and performance of the Reva Fantom Sirolismus-Eluting Bioresorbable Coronary Scaffold in nativ coronary arteries that includes incorporation of a deformable expansion technologgy and an enhanced scaffold material (Tyr...

Klinische Forschung - 06.05.2024 - 30.06.2030

Laufend

Projektleitung: Rigger Johannes
Mitarbeiter/innen: Fink Karin, Schneider Irene

A prospective, randomized, multicenter, international, open, clinical study in which the SELUTION DEB strategy was compared with the DES strategy. Study objectives: 1) At 1 year, to demonstrate non-inferiority for TVF of a treatment strategy wi...

Klinische Forschung - 28.09.2023 - 28.09.2028

Laufend

Projektleitung: Rigger Johannes
Mitarbeiter/innen: Meier Jessica, Schneider Irene

The aim of the Swiss-CARE registry is a comprehensive collection of clinical data and a follow-up of patients diagnosed with cardiac amyloidosis. Patients with and without therapy will be included in the registry. This will allow us to better under...

Register - 01.07.2023 - 01.07.2033

Laufend

Projektleitung: Ehl Niklas
Mitarbeiter/innen: Schneider Irene

The rationale of this prospective longitudinal cohort study is to determine the short and long-term effects of an ambulatory cardiac rehabilitation program on key cardiovascular benchmark performance measures and its effects on major adverse cardiova...

Register - 01.07.2023 - 31.12.2040

Laufend

Projektleitung: Buser Marc
Mitarbeiter/innen: Schneider Irene

A longitudinal observational study of patients treated with the MitraClip system in Switzerland

Register - 01.04.2022 - 31.12.2030

Laufend

Projektleitung: Haager Philipp
Mitarbeiter/innen: Schneider Irene

This study is a multinational, multicentre, non-interventional, cohort study of assessment and treatment guideline recommendations in HF patient care in a real-world setting.

Klinische Forschung - 30.09.2021 - 31.12.2025

Abgeschlossen

Projektleitung: Maeder Micha
Mitarbeiter/innen: Vetsch Susanne, Schneider Irene

Atrial fibrillation before and after patent foramen ovale closure study This is a prospective, multicenter, single-arm, observational study assessing the incidence, predictors and prognostic impact of AF occurring before (monitoring phase A) or af...

Klinische Forschung - 23.06.2021 - 23.06.2027

Laufend

Projektleitung: Chronis Joannis
Mitarbeiter/innen: Schneider Irene, Vetsch Susanne

We aim to: 1. Assess preclinical cardiac dysfunction longitudinally using 2-dimensional (2D) and 3-dimensional (3D) conventional and 2D speckle tracking echocardiography. 2. Assess cardiopulmonary fitness using cardiopulmonary exercise testing. 3....

Klinische Forschung - 01.03.2021 - 31.12.2030

Laufend

Projektleitung: Scheler Eva
Mitarbeiter/innen: Schneider Irene

To test in a multicenter open-label randomized controlled trial across Switzerland whether a cascade screening programme for FH, in comparison with usual care, will increase the detection rate of FH within families. The primary outcome will be the...

Klinische Forschung - 15.12.2020 - 31.03.2024

Abgeschlossen

Projektleitung: Rickli Hans
Mitarbeiter/innen: Vetsch Susanne, Schneider Irene

Incidence of Silent Atrial Fibrillation in Patients With Clinically Silent Brain Ischemic Lesions Arterial Fibrillation (AF) is well-recognized as a cause for cryptogenic Acute Ischemic Stroke (AIS) and is associated with Silent Brain Infarction...

Klinische Forschung - 04.12.2020 - 04.12.2024

Automatisch geschlossen

Projektleitung: Ammann Peter, Kägi Georg
Mitarbeiter/innen: Brenner Roman, Vetsch Susanne, Schneider Irene

The primary aim is to gather observational data from consecutive SCAD patients in Switzerland, in order to establish a National Swiss Registry (SwissSCAD). SCAD is a poorly understood condition, affecting young patients and is associated with major...

Klinische Forschung - 01.10.2020 - 31.12.2030

Laufend

Projektleitung: Rickli Hans
Mitarbeiter/innen: Schneider Irene

Post-market registry to evaluate the safety and efficacy of the Supraflex Cruz™ sirolimus-eluting coronary stent system in the treatment of all-comer patients with coronary artery disease

Klinische Forschung - 13.07.2020 - 31.12.2022

Abgeschlossen

Projektleitung: Weilenmann Daniel
Mitarbeiter/innen: Schneider Irene, Fink Karin

This study is a post-market clinical follow-up (PMCF) study to identify and evaluate residual risks associated with the use of the BIOMONITOR III that are discovered or remain even after risk analysis, risk mitigation and successful conformity assess...

Klinische Forschung - 10.02.2020 - 21.01.2022

Abgeschlossen

Projektleitung: Ammann Peter
Mitarbeiter/innen: Schneider Irene

Ziele: Aus den klinischen Daten (Anamnese, körperliche Untersuchung und einem der Ischämietests [Ergometrie, Stress-Echo, Stress MRI) wird mit einer logistischen Regression eine Wahrscheinlichkeits-funktion abgeleitet. Als Referenzuntersuchung gelten...

Klinische Forschung - 01.02.2019 - 31.03.2022

Abgeschlossen

Projektleitung: Rickli Hans
Mitarbeiter/innen: Schneider Irene

Titel: instantaneous wave-free ratio guided Multivessel revascularizatiOn During percutaneous coronary intervEntion for acute myocaRdial iNfarction Objective: To compare an iFR-guided intervention of noninfarct lesions during the acute interventi...

Klinische Forschung - 20.01.2019 - 31.12.2024

Laufend

Projektleitung: Rigger Johannes
Mitarbeiter/innen: Schneider Irene

The aim of the BIOSOLVE - IV Swiss Satellite Registry is to investigate the clinical performance and long-term safety of Magmaris in a real world setting and extend clinical practice using the technology in a monitored nationwide registry. Primary En...

Klinische Forschung - 01.11.2018 - 31.03.2022

Abgebrochen

Projektleitung: Jörg Lucas
Mitarbeiter/innen: Schneider Irene

Takotsubo Cardiomyopathy, or broken heart syndrome, is a recently described acquired form of cardiomyopathy whose pathophysiology is not well understood and particularly affects postmenopausal women. The exact mechanism is still unclear and large p...

Klinische Forschung - 01.04.2018 - 31.12.2030

Laufend

Projektleitung: Jörg Lucas
Mitarbeiter/innen: Fink Karin, Schneider Irene

To assess the long term safety and efficacy of the XPOSITION S STENT in routine clinical practice. Inclusion of subjects with coronary artery disease, including patients with chronic stable angina, silent ischemia and acute coronary syndrome, who qua...

Klinische Forschung - 27.01.2017 - 31.01.2020

Abgeschlossen

Projektleitung: Weilenmann Daniel
Mitarbeiter/innen: Schneider Irene

Mit dieser Studie wird die Sicherheit und Effektivität von zwei medikamentenbeschichteten Stents bei Patienten, die einen STEMI erlitten haben verglichen. Es wird geprüft, ob der Stent mit einer selbst auflösenden Beschichtung bei Patienten mit einem...

Klinische Forschung - 12.10.2016 - 30.12.2023

Abgeschlossen

Projektleitung: Weilenmann Daniel
Mitarbeiter/innen: Schneider Irene