The present project has several objectives. Our main goal is to evaluate the hemodynamic characteristics in particular the mean pulmonary artery wedge pressure (mPAWP) of patients with versus without bendopnea and those with high (supramedian) vers...

Clinical Studies - Jul 1, 2024 - Jun 30, 2026

Ongoing

Project leader: Maeder Micha
Members: Schneider Irene

To evaluate the continued safety and performance of the Reva Fantom Sirolismus-Eluting Bioresorbable Coronary Scaffold in nativ coronary arteries that includes incorporation of a deformable expansion technologgy and an enhanced scaffold material (Tyr...

Clinical Studies - May 6, 2024 - Jun 30, 2030

Ongoing

Project leader: Rigger Johannes
Members: Fink Karin, Schneider Irene

A prospective, randomized, multicenter, international, open, clinical study in which the SELUTION DEB strategy was compared with the DES strategy. Study objectives: 1) At 1 year, to demonstrate non-inferiority for TVF of a treatment strategy wi...

Clinical Studies - Sep 28, 2023 - Sep 28, 2028

Ongoing

Project leader: Rigger Johannes
Members: Meier Jessica, Schneider Irene

The aim of the Swiss-CARE registry is a comprehensive collection of clinical data and a follow-up of patients diagnosed with cardiac amyloidosis. Patients with and without therapy will be included in the registry. This will allow us to better under...

Register - Jul 1, 2023 - Jul 1, 2033

Ongoing

Project leader: Ehl Niklas
Members: Schneider Irene

The rationale of this prospective longitudinal cohort study is to determine the short and long-term effects of an ambulatory cardiac rehabilitation program on key cardiovascular benchmark performance measures and its effects on major adverse cardiova...

Register - Jul 1, 2023 - Dec 31, 2040

Ongoing

Project leader: Buser Marc
Members: Schneider Irene

A longitudinal observational study of patients treated with the MitraClip system in Switzerland

Register - Apr 1, 2022 - Dec 31, 2030

Ongoing

Project leader: Haager Philipp
Members: Schneider Irene

This study is a multinational, multicentre, non-interventional, cohort study of assessment and treatment guideline recommendations in HF patient care in a real-world setting.

Clinical Studies - Sep 30, 2021 - Dec 31, 2025

Completed

Project leader: Maeder Micha
Members: Vetsch Susanne, Schneider Irene

Atrial fibrillation before and after patent foramen ovale closure study This is a prospective, multicenter, single-arm, observational study assessing the incidence, predictors and prognostic impact of AF occurring before (monitoring phase A) or af...

Clinical Studies - Jun 23, 2021 - Jun 23, 2027

Ongoing

Project leader: Chronis Joannis
Members: Schneider Irene, Vetsch Susanne

We aim to: 1. Assess preclinical cardiac dysfunction longitudinally using 2-dimensional (2D) and 3-dimensional (3D) conventional and 2D speckle tracking echocardiography. 2. Assess cardiopulmonary fitness using cardiopulmonary exercise testing. 3....

Clinical Studies - Mar 1, 2021 - Dec 31, 2030

Ongoing

Project leader: Scheler Eva
Members: Schneider Irene

To test in a multicenter open-label randomized controlled trial across Switzerland whether a cascade screening programme for FH, in comparison with usual care, will increase the detection rate of FH within families. The primary outcome will be the...

Clinical Studies - Dec 15, 2020 - Mar 31, 2024

Completed

Project leader: Rickli Hans
Members: Vetsch Susanne, Schneider Irene

Incidence of Silent Atrial Fibrillation in Patients With Clinically Silent Brain Ischemic Lesions Arterial Fibrillation (AF) is well-recognized as a cause for cryptogenic Acute Ischemic Stroke (AIS) and is associated with Silent Brain Infarction...

Clinical Studies - Dec 4, 2020 - Dec 4, 2024

Automatically Closed

Project leader: Ammann Peter, Kägi Georg
Members: Brenner Roman, Vetsch Susanne, Schneider Irene

The primary aim is to gather observational data from consecutive SCAD patients in Switzerland, in order to establish a National Swiss Registry (SwissSCAD). SCAD is a poorly understood condition, affecting young patients and is associated with major...

Clinical Studies - Oct 1, 2020 - Dec 31, 2030

Ongoing

Project leader: Rickli Hans
Members: Schneider Irene

Post-market registry to evaluate the safety and efficacy of the Supraflex Cruz™ sirolimus-eluting coronary stent system in the treatment of all-comer patients with coronary artery disease

Clinical Studies - Jul 13, 2020 - Dec 31, 2022

Completed

Project leader: Weilenmann Daniel
Members: Schneider Irene, Fink Karin

This study is a post-market clinical follow-up (PMCF) study to identify and evaluate residual risks associated with the use of the BIOMONITOR III that are discovered or remain even after risk analysis, risk mitigation and successful conformity assess...

Clinical Studies - Feb 10, 2020 - Jan 21, 2022

Completed

Project leader: Ammann Peter
Members: Schneider Irene

Ziele: Aus den klinischen Daten (Anamnese, körperliche Untersuchung und einem der Ischämietests [Ergometrie, Stress-Echo, Stress MRI) wird mit einer logistischen Regression eine Wahrscheinlichkeits-funktion abgeleitet. Als Referenzuntersuchung gelten...

Clinical Studies - Feb 1, 2019 - Mar 31, 2022

Completed

Project leader: Rickli Hans
Members: Schneider Irene

Titel: instantaneous wave-free ratio guided Multivessel revascularizatiOn During percutaneous coronary intervEntion for acute myocaRdial iNfarction Objective: To compare an iFR-guided intervention of noninfarct lesions during the acute interventi...

Clinical Studies - Jan 20, 2019 - Dec 31, 2024

Ongoing

Project leader: Rigger Johannes
Members: Schneider Irene

The aim of the BIOSOLVE - IV Swiss Satellite Registry is to investigate the clinical performance and long-term safety of Magmaris in a real world setting and extend clinical practice using the technology in a monitored nationwide registry. Primary En...

Clinical Studies - Nov 1, 2018 - Mar 31, 2022

Aborted

Project leader: Jörg Lucas
Members: Schneider Irene

Takotsubo Cardiomyopathy, or broken heart syndrome, is a recently described acquired form of cardiomyopathy whose pathophysiology is not well understood and particularly affects postmenopausal women. The exact mechanism is still unclear and large p...

Clinical Studies - Apr 1, 2018 - Dec 31, 2030

Ongoing

Project leader: Jörg Lucas
Members: Fink Karin, Schneider Irene

To assess the long term safety and efficacy of the XPOSITION S STENT in routine clinical practice. Inclusion of subjects with coronary artery disease, including patients with chronic stable angina, silent ischemia and acute coronary syndrome, who qua...

Clinical Studies - Jan 27, 2017 - Jan 31, 2020

Completed

Project leader: Weilenmann Daniel
Members: Schneider Irene

Mit dieser Studie wird die Sicherheit und Effektivität von zwei medikamentenbeschichteten Stents bei Patienten, die einen STEMI erlitten haben verglichen. Es wird geprüft, ob der Stent mit einer selbst auflösenden Beschichtung bei Patienten mit einem...

Clinical Studies - Oct 12, 2016 - Dec 30, 2023

Completed

Project leader: Weilenmann Daniel
Members: Schneider Irene