Torsten Olszak
Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression.
Stallhofer J, Veith L, Diegelmann J, Probst P, Brand S, Schnitzler F, Olszak T, Török H, Mayerle J, Stallmach A, Beigel F. Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression. Clin Transl Gastroenterol 2022; 13:e00450.
13.01.2022Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression.
13.01.2022Clin Transl Gastroenterol 2022; 13:e00450
Stallhofer Johannes, Veith Lisa, Diegelmann Julia, Probst Philipp, Brand Stephan, Schnitzler Fabian, Olszak Torsten, Török Helga P, Mayerle Julia, Stallmach Andreas, Beigel Florian
Development of a uniform, very aggressive disease phenotype in all homozygous carriers of the NOD2 mutation p.Leu1007fsX1008 with Crohn's disease and active smoking status resulting in ileal stenosis requiring surgery.
Schnitzler F, Friedrich M, Angelberger M, Diegelmann J, Stallhofer J, Wolf C, Dütschler J, Truniger S, Olszak T, Beigel F, Tillack C, Lohse P, Brand S. Development of a uniform, very aggressive disease phenotype in all homozygous carriers of the NOD2 mutation p.Leu1007fsX1008 with Crohn's disease and active smoking status resulting in ileal stenosis requiring surgery. PloS one 2020; 15:e0236421.
27.07.2020Development of a uniform, very aggressive disease phenotype in all homozygous carriers of the NOD2 mutation p.Leu1007fsX1008 with Crohn's disease and active smoking status resulting in ileal stenosis requiring surgery.
27.07.2020PloS one 2020; 15:e0236421
Schnitzler Fabian, Friedrich Matthias, Angelberger Marianne, Diegelmann Julia, Stallhofer Johannes, Wolf Christiane, Dütschler Joel, Truniger Samuel, Olszak Torsten, Beigel Florian, Tillack Cornelia, Lohse Peter, Brand Stephan
Solid Organ Transplantation in Patients with Inflammatory Bowel Diseases (IBD): Analysis of Transplantation Outcome and IBD Activity in a Large Single Center Cohort
Schnitzler F, Grüner N, Rust C, Guba M, Denk G, Zachoval R, Göke B, Tillack C, Beigel F, Olszak T, Angelberger M, Wolf C, Karbalai N, Habicht A, Fischereder M, Schönermarck U, Stallhofer J, Friedrich M, Brand S. Solid Organ Transplantation in Patients with Inflammatory Bowel Diseases (IBD): Analysis of Transplantation Outcome and IBD Activity in a Large Single Center Cohort. PloS one 2015; 10:e0135807.
19.08.2015Solid Organ Transplantation in Patients with Inflammatory Bowel Diseases (IBD): Analysis of Transplantation Outcome and IBD Activity in a Large Single Center Cohort
19.08.2015PloS one 2015; 10:e0135807
Schnitzler Fabian, Grüner Norbert, Rust Christian, Guba Markus, Denk Gerald, Zachoval Reinhart, Göke Burkhard, Tillack Cornelia, Beigel Florian, Olszak Torsten, Angelberger Marianne, Wolf Christiane, Karbalai Nazanin, Habicht Antje, Fischereder Michael, Schönermarck Ulf, Stallhofer Johannes, Friedrich Matthias, Brand Stephan
The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations
Schnitzler F, Lohse P, Glas J, Göke B, Beigel F, Tillack C, Olszak T, Diegelmann J, Angelberger M, Stallhofer J, Wolf C, Friedrich M, Brand S. The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations. PloS one 2015; 10:e0116044.
06.07.2015The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations
06.07.2015PloS one 2015; 10:e0116044
Schnitzler Fabian, Lohse Peter, Glas Jürgen, Göke Burkhard, Beigel Florian, Tillack Cornelia, Olszak Torsten, Diegelmann Julia, Angelberger Marianne, Stallhofer Johannes, Wolf Christiane, Friedrich Matthias, Brand Stephan
The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067
Schnitzler F, Lohse P, Glas J, Göke B, Stallhofer J, Tillack C, Beigel F, Olszak T, Diegelmann J, Angelberger M, Wolf C, Friedrich M, Brand S. The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067. PloS one 2014; 9:e108503.
03.11.2014The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067
03.11.2014PloS one 2014; 9:e108503
Schnitzler Fabian, Lohse Peter, Glas Jürgen, Göke Burkhard, Stallhofer Johannes, Tillack Cornelia, Beigel Florian, Olszak Torsten, Diegelmann Julia, Angelberger Marianne, Wolf Christiane, Friedrich Matthias, Brand Stephan
Protective mucosal immunity mediated by epithelial CD1d and IL-10
Olszak T, Nakajima A, Mizuguchi H, Kawasaki K, Nagata K, Müller W, Snapper S, Schreiber S, Kaser A, Zeissig S, Katayama K, Wada K, Neves J, Dowds C, Baker K, Glickman J, Davidson N, Lin C, Jobin C, Brand S, Sotlar K, Blumberg R. Protective mucosal immunity mediated by epithelial CD1d and IL-10. Nature 2014; 509:497-502.
06.04.2014Protective mucosal immunity mediated by epithelial CD1d and IL-10
06.04.2014Nature 2014; 509:497-502
Olszak Torsten, Nakajima Atsushi, Mizuguchi Hiroyuki, Kawasaki Kunito, Nagata Kazuhiro, Müller Werner, Snapper Scott B, Schreiber Stefan, Kaser Arthur, Zeissig Sebastian, Katayama Kazufumi, Wada Koichiro, Neves Joana F, Dowds C Marie, Baker Kristi, Glickman Jonathan, Davidson Nicholas O, Lin Chyuan-Sheng, Jobin Christian, Brand Stephan, Sotlar Karl, Blumberg Richard S
Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2
Diegelmann J, Glas J, Franke A, Göke B, Bedynek A, Olszak T, Zimmermann E, Le Bras E, Czamara D, Brand S. Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2. PloS one 2013; 8:e77773.
05.11.2013Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2
05.11.2013PloS one 2013; 8:e77773
Diegelmann Julia, Glas Jürgen, Franke Andre, Göke Burkhard, Bedynek Andrea, Olszak Torsten, Zimmermann Eva, Le Bras Emmanuelle, Czamara Darina, Brand Stephan
IRGM variants and susceptibility to inflammatory bowel disease in the German population
Glas J, Czamara D, Diegelmann J, Göke B, Friedrich M, Steib C, Beigel F, Wetzke M, Tsekeri E, Olszak T, Fries C, Stallhofer J, Bues S, Seiderer J, Brand S. IRGM variants and susceptibility to inflammatory bowel disease in the German population. PloS one 2013; 8:e54338.
24.01.2013IRGM variants and susceptibility to inflammatory bowel disease in the German population
24.01.2013PloS one 2013; 8:e54338
Glas Jürgen, Czamara Darina, Diegelmann Julia, Göke Burkhard, Friedrich Matthias, Steib Christian, Beigel Florian, Wetzke Martin, Tsekeri Eleni, Olszak Torsten, Fries Christoph, Stallhofer Johannes, Bues Stephanie, Seiderer Julia, Brand Stephan
PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites
Glas J, Duerr R, Franke A, Kamboh M, Achkar J, Balschun T, Müller-Myhsok B, Wolf C, Olszak T, Wetzke M, Diegelmann J, Pasciuto G, Czamara D, Seiderer J, Brand S. PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites. PloS one 2012; 7:e52873.
27.12.2012PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites
27.12.2012PloS one 2012; 7:e52873
Glas Jürgen, Duerr Richard H, Franke Andre, Kamboh M Ilyas, Achkar Jean-Paul, Balschun Tobias, Müller-Myhsok Bertram, Wolf Christiane, Olszak Torsten, Wetzke Martin, Diegelmann Julia, Pasciuto Giulia, Czamara Darina, Seiderer Julia, Brand Stephan
Analysis of IL12B gene variants in inflammatory bowel disease
Glas J, Czamara D, Diegelmann J, Ochsenkühn T, Göke B, Wetzke M, Steib C, Stallhofer J, Beigel F, Friedrich M, Tillack C, Fries C, Olszak T, Wagner J, Seiderer J, Brand S. Analysis of IL12B gene variants in inflammatory bowel disease. PloS one 2012; 7:e34349.
30.03.2012Analysis of IL12B gene variants in inflammatory bowel disease
30.03.2012PloS one 2012; 7:e34349
Glas Jürgen, Czamara Darina, Diegelmann Julia, Ochsenkühn Thomas, Göke Burkhard, Wetzke Martin, Steib Christian, Stallhofer Johannes, Beigel Florian, Friedrich Matthias, Tillack Cornelia, Fries Christoph, Olszak Torsten, Wagner Johanna, Seiderer Julia, Brand Stephan
PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background
Glas J, Czamara D, Diegelmann J, Karbalai N, Ochsenkühn T, Göke B, Steib C, Friedrich M, Stallhofer J, Tillack C, Beigel F, Wetzke M, Olszak T, Seiderer J, Wagner J, Brand S. PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background. PloS one 2012; 7:e33682.
21.03.2012PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background
21.03.2012PloS one 2012; 7:e33682
Glas Jürgen, Czamara Darina, Diegelmann Julia, Karbalai Nazanin, Ochsenkühn Thomas, Göke Burkhard, Steib Christian, Friedrich Matthias, Stallhofer Johannes, Tillack Cornelia, Beigel Florian, Wetzke Martin, Olszak Torsten, Seiderer Julia, Wagner Johanna, Brand Stephan
The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease
Glas J, Czamara D, Diegelmann J, Friedrich M, Steib C, Beigel F, Olszak T, Tillack C, Fries C, Wetzke M, Bayrle C, Seiderer J, Brand S. The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease. PloS one 2011; 6:e29309.
29.12.2011The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease
29.12.2011PloS one 2011; 6:e29309
Glas Jürgen, Czamara Darina, Diegelmann Julia, Friedrich Matthias, Steib Christian, Beigel Florian, Olszak Torsten, Tillack Cornelia, Fries Christoph, Wetzke Martin, Bayrle Corinna, Seiderer Julia, Brand Stephan
A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory proteins
Diegelmann J, Olszak T, Göke B, Blumberg R, Brand S. A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory proteins. J Biol Chem 2011; 287:286-98.
08.11.2011A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory proteins
08.11.2011J Biol Chem 2011; 287:286-98
Diegelmann Julia, Olszak Torsten, Göke Burkhard, Blumberg Richard S, Brand Stephan
CEACAM6 gene variants in inflammatory bowel disease
Glas J, Czamara D, Diegelmann J, Müller-Myhsok B, Lohse P, Wolf C, Ochsenkühn T, Göke B, Lass U, Olszak T, Beigel F, Weidinger M, Pfennig S, Tillack C, Fries C, Seiderer J, Brand S. CEACAM6 gene variants in inflammatory bowel disease. PloS one 2011; 6:e19319.
29.04.2011CEACAM6 gene variants in inflammatory bowel disease
29.04.2011PloS one 2011; 6:e19319
Glas Jürgen, Czamara Darina, Diegelmann Julia, Müller-Myhsok Bertram, Lohse Peter, Wolf Christiane, Ochsenkühn Thomas, Göke Burkhard, Lass Ulrich, Olszak Torsten, Beigel Florian, Weidinger Maria, Pfennig Simone, Tillack Cornelia, Fries Christoph, Seiderer Julia, Brand Stephan
The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants
Glas J, Czamara D, Diegelmann J, Lohse P, Ochsenkühn T, Göke B, Müller-Myhsok B, Weidinger M, Laubender R, Olszak T, Jürgens M, Beigel F, Pfennig S, Tillack C, Seiderer J, Brand S. The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants. PloS one 2010; 5:e14466.
30.12.2010The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants
30.12.2010PloS one 2010; 5:e14466
Glas Jürgen, Czamara Darina, Diegelmann Julia, Lohse Peter, Ochsenkühn Thomas, Göke Burkhard, Müller-Myhsok Bertram, Weidinger Maria, Laubender Rüdiger P, Olszak Torsten, Jürgens Matthias, Beigel Florian, Pfennig Simone, Tillack Cornelia, Seiderer Julia, Brand Stephan
Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease
Glas J, Czamara D, Diegelmann J, Müller-Myhsok B, Folwaczny M, Ochsenkühn T, Göke B, Weidinger M, Olszak T, Beigel F, Wetzke M, Pfennig S, Tengler B, Fischer D, Seiderer J, Brand S. Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease. Inflamm Bowel Dis 2010; 17:1917-24.
03.12.2010Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease
03.12.2010Inflamm Bowel Dis 2010; 17:1917-24
Glas Jürgen, Czamara Darina, Diegelmann Julia, Müller-Myhsok Bertram, Folwaczny Matthias, Ochsenkühn Thomas, Göke Burkhard, Weidinger Maria, Olszak Torsten, Beigel Florian, Wetzke Martin, Pfennig Simone, Tengler Barbara, Fischer Daniel, Seiderer Julia, Brand Stephan
IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro
Brand S, Thasler W, Bilzer M, Diepolder H, Göke B, Storr M, Steib C, Olszak T, Prüfer T, Weiss T, Heeg M, Zitzmann K, Beigel F, Dambacher J, Auernhammer C. IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro. Am J Physiol Gastrointest Liver Physiol 2007; 292:G1019-28.
04.01.2007IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro
04.01.2007Am J Physiol Gastrointest Liver Physiol 2007; 292:G1019-28
Brand Stephan, Thasler Wolfgang E, Bilzer Manfred, Diepolder Helmut, Göke Burkhard, Storr Martin, Steib Christian J, Olszak Torsten, Prüfer Thomas, Weiss Thomas S, Heeg Malte H J, Zitzmann Kathrin, Beigel Florian, Dambacher Julia, Auernhammer Christoph J
IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
Brand S, Auernhammer C, Göke B, Ochsenkühn T, Seiderer J, Herrmann K, Leclair S, Popp A, Jagla W, Marquardt A, Diepolder H, Otte J, Eichhorst S, Zitzmann K, Olszak T, Beigel F, Dambacher J. IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. Am J Physiol Gastrointest Liver Physiol 2006; 290:G827-38.
01.04.2006IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration
01.04.2006Am J Physiol Gastrointest Liver Physiol 2006; 290:G827-38
Brand Stephan, Auernhammer Christoph J, Göke Burkhard, Ochsenkühn Thomas, Seiderer Julia, Herrmann Karin, Leclair Stéphane, Popp Andreas, Jagla Wolfgang, Marquardt Andreas, Diepolder Helmut, Otte Jan-Michel, Eichhorst Sören T, Zitzmann Kathrin, Olszak Torsten, Beigel Florian, Dambacher Julia
Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells
Brand S, Olszak T, Beigel F, Diebold J, Otte J, Eichhorst S, Göke B, Dambacher J. Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells. J Cell Biochem 2006; 97:709-23.
01.03.2006Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells
01.03.2006J Cell Biochem 2006; 97:709-23
Brand Stephan, Olszak Torsten, Beigel Florian, Diebold Joachim, Otte Jan-Michel, Eichhorst Soeren T, Göke Burkhard, Dambacher Julia
CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation
Brand S, Dambacher J, Beigel F, Olszak T, Diebold J, Otte J, Göke B, Eichhorst S. CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation. Exp Cell Res 2005; 310:117-30.
15.10.2005CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation
15.10.2005Exp Cell Res 2005; 310:117-30
Brand Stephan, Dambacher Julia, Beigel Florian, Olszak Torsten, Diebold Joachim, Otte Jan-Michel, Göke Burkhard, Eichhorst Sören T