Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression.

Publikation

Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression.

Wissenschaftlicher Artikel/Review - 13.01.2022

Stallhofer Johannes, Veith Lisa, Diegelmann Julia, Probst Philipp, Brand Stephan, Schnitzler Fabian, Olszak Torsten, Török Helga P, Mayerle Julia, Stallmach Andreas, Beigel Florian

Zitation

Stallhofer J, Veith L, Diegelmann J, Probst P, Brand S, Schnitzler F, Olszak T, Török H, Mayerle J, Stallmach A, Beigel F. Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression. Clin Transl Gastroenterol 2022; 13:e00450.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Clin Transl Gastroenterol 2022; 13

Veröffentlichungsdatum

13.01.2022

eISSN (Online)

2155-384X

Seiten

e00450

Kurzbeschreibung/Zielsetzung

Iron deficiency and vitamin D deficiency are common comorbidities in inflammatory bowel disease (IBD). Accumulating evidence indicates that active 1,25-dihydroxyvitamin D (1,25(OH)D) may enhance iron absorption by suppressing hepcidin. We investigated the influence of vitamin D on iron metabolism in patients with IBD and on the expression of genes facilitating intestinal epithelial iron absorption.