Unit
Neurologie
NL · Dept. III
Clinical and MRI based predictors of prolonged dysphagia in ischemic stroke
Jan 1, 2013Background With an incidence of approximately 55% swallowing disorders after ischemic stroke are a regular issue and can lead to complications like pneumonia, malnutrition and dehydration. The presence of dysphagia in stroke patients may be associat...
Clinical Studies - Jan 1, 2013 - Jul 31, 2014
Completed
Project leader: Kägi Georg
Members: Galovic Marian, Weder Bruno, Stöckli Sandro, Leisi Natascha, Müller Marlise, Weber Johannes
Swiss Multiple Sclerosis Cohort-Study (SMSC-Study): A Prospective Swiss wide Investigation of Key Phases in Disease Evolution and new Treatment options
Jan 1, 2013The key aims of the Swiss Multiple Sclerosis Cohort-Study (SMSC) are (1) To maintain a long-term cohort (>10 years) representative of the MS population currently living in Switzerland. This requires effective measures to limit drop-outs and the conti...
Clinical Studies - Jan 1, 2013 - Nov 30, 2022
Automatically Closed
Project leader: Müller Stefanie
Romanian-Swiss-Cooperation Program: IZERZ0_142226: Integration of medical oncology and palliative care procedures in various institutional and economical settings
Jan 1, 2013Summary of the research plan Background: In the care of advanced incurable cancer patients medical oncologists play a sentinel role in not only providing tumour directed treatment, but also in identifying and treating palliative care needs. In busy o...
Clinical Studies - Jan 1, 2013 - Dec 31, 2015
Completed
Project leader: Strasser Florian
Members: Wilm Simone, Magayakalbermatten N
SMiLE-Lebenssinn, persönliche Werte und Spiritualität bei Patienten mit lebensbedrohlichen Erkrankungen (NFP 67)
Nov 1, 2012Zusammenfassung des Studienprotokolls Principal Investigator : Professor Gian Domenico Borasio, Universitätsspital Lausanne Co-Investigatoren : Mathieu Bernhard, Universitätsspital Lausanne; Dr. Claudia Gamondi Palmesino, Regionalspital Bellinzona...
Clinical Studies - Nov 1, 2012 - Oct 31, 2014
Completed
Project leader: Strasser Florian
Members: Wilm Simone, Magayakalbermatten N
pre-MENAC
Oct 28, 2012
Clinical Studies - Oct 28, 2012 - Sep 26, 2013
Completed
Project leader: Strasser Florian
Members: Wilm Simone, Magayakalbermatten N
Biomarkes Cancer Cachexia in Urin and Blood
Oct 14, 2012Urin
Fundamental Research - Oct 14, 2012 - Dec 15, 2012
Aborted
Project leader: Strasser Florian
Members: Demmer-Steingruber Ruth, Wilm Simone
Decision criteria guiding chemotherapy in palliative intention: prospective study comparing patients, doctors’, and nurses responses- KLS -02785-02-2011
Sep 1, 2012Die Wirksamkeit von Krebstherapien für Patienten mit fortgeschrittenen, unheilbaren Krebserkran-kungen wurde in klinischen Studien untersucht, hauptsächlich bezüglich der Beeinflussung des Tumorwachstums, des Ueberlebens, und der Verträglichkeit der...
Clinical Studies - Sep 1, 2012 - May 31, 2014
Automatically Closed
Project leader: Strasser Florian
Members: Wilm Simone, Magayakalbermatten N
Avastin plus Radiotherapy in Elderly Patients with Glioblastoma (ARTE) A phase II, randomized, parallel-group, explorative, open labeled multi-center study of bevacizumab (Avastin®) in elderly subjects with newly diagnosed glioblastoma
Aug 17, 2012Die Prognose von Patienten, die an einem Glioblastom erkranken, ist sehr schlecht, insbesondere bei älteren Patienten. Derzeit gilt die Strahlentherapie als Standardtherapie nach der Operation mit einer medianen Überlebenszeit von etwa 6 Monaten. Ein...
Clinical Studies - Aug 17, 2012 - May 30, 2015
Completed
Project leader: Plasswilm Ludwig
Members: Weder Patrik, Hundsberger Thomas
Long-term, prospective, observational, multinational, parallel-cohort study monitoring safety in patients with MS newly started with fingolimod once daily or treated with another approved disease-modifying therapy - FTY720
May 20, 2012Long-term, prospective, observational, multinational, parallel-cohort study monitoring safety in patients with MS newly started with fingolimod once daily or treated with another approved disease-modifying therapy Study: FTY720 - 2403
Clinical Studies - May 20, 2012 - Dec 31, 2018
Automatically Closed
Project leader: Müller Stefanie
An observational study to assess persistence, adherence, quality of life, and treatment satisfaction in patients beginning therapy with the Avonex® PEN™
Apr 1, 2012An observational study to assess persistence, adherence, quality of life, and treatment satisfaction in patients beginning therapy with the Avonex® PEN™
Clinical Studies - Apr 1, 2012 - Apr 1, 2013
Completed
Project leader: Müller Stefanie
A 32-week, patient- and rater-blinded, randomized, multicenter, parallel-group study to evaluate disease control and safety in patients with relapsing remitting multiple sclerosis transferred from previous treatment with natalizumab to fingolimod (FTY720)
Apr 1, 2012A 32-week, patient- and rater-blinded, randomized, multicenter, parallel-group study to evaluate disease control and safety in patients with relapsing remitting multiple sclerosis transferred from previous treatment with natalizumab to fingolimod (FT...
Clinical Studies - Apr 1, 2012 - Dec 1, 2012
Aborted
Project leader: Müller Stefanie
A randomized, double-blind, placebo-controlled multi-center study of BYM338 for treatment of cachexia in patients with stage IV non-small cell lung cancer or stage III/IV adenocarcinoma of the pancreas - EKSG 11/084
Jan 9, 2012Ein ungewollter Gewichtsverlust (Kachexie) ist bei vielen Krebsformen ein unabhängiges Anzeichen für ein kürzeres Gesamtüberleben, selbst vor Beginn einer Chemotherapie. Patienten mit Gewichtsverlust entwickeln zudem häufig stärkere Nebenwirkungen wä...
Clinical Studies - Jan 9, 2012 - Jul 31, 2012
Completed
Project leader: Strasser Florian
Members: Jörger Markus, Gueller Ulrich, Wilm Simone
Prospektives durch Langzeitbeobachtung erstelltes Sicherheitsregister von Patienten mit Multipler Sklerose, die an klinischen Versuchen mit Cladribine teilgenommen haben
Dec 20, 2011
Clinical Studies - Dec 20, 2011 - Dec 31, 2015
Completed
Project leader: Hundsberger Thomas
Pilotstudie: Die Bedeutung der supplementär-motorischen Area bei der Pathophysiologie des Freezing of Gait beim Morbus Parkinson
Dec 1, 2011Das Freezing of Gait (FOG) stellt ein schwerwiegendes und invalidisierendes Symptom beim fortgeschrittenen Morbus Parkinson dar, da es aufgrund seines paroxysmalen Auftretens den Patienten in seiner Mobilität einschränkt. FOG führt ausserdem vermehrt...
Clinical Studies - Dec 1, 2011 - Jun 30, 2013
Completed
Project leader: Kägi Georg, Brugger Florian
Members: Bohlhalter Stephan, Wegener Regina, Hägele-Link Stefan, Abela Eugenio
Development of a module to supplement the EORTC Core instruments for assessment of Health Related Quality of Life in patients with Cancer Cachexia - EKSG 12/091; CTU 12-11
Dec 1, 2011Aims 1. To develop a module to supplement the EORTC QLQ core module, for the assessment of QoL in patients with cancer cachexia. 2. To explore the possible need for parallel development of separate modules for cachexia syndrome, refractory cachexia...
Clinical Studies - Dec 1, 2011 - Dec 31, 2016
Automatically Closed
Project leader: Strasser Florian
Members: Wilm Simone
Systematic Literature Review Population and Outcomes of Clinical Trials in Cachexia
Sep 26, 2011
Clinical Studies - Sep 26, 2011 - Sep 26, 2014
Completed
Project leader: Strasser Florian
Members: Wilm Simone
multicenter, double-blind, placebo-controlled, parallel-group, phase IV study to assess the effect of Rotigotine on non-motor symptoms in patients with idiopathic parkinson's disease
Sep 1, 2011Multizentrische, doppelblinde, placebokontrollierte Parallelgruppenstudie der Phase IV zur Bestimmung der Wirkung von Rotigotin auf die nichtmotorischen Symptome bei Patienten mit idiopathischem Parkinson-Syndrom Studie SP0976
Clinical Studies - Sep 1, 2011 - Dec 31, 2012
Automatically Closed
Project leader: Tettenborn Barbara
Members: Kägi Georg, Brugger Florian, Hägele-Link Stefan
Pilot study on the effect of escitalopram on cortical plasticity and glutamate transmission in healthy subjects: A neurophysiological and Magnet Resonance Spectroscopy study
Jul 1, 2011After ischemic stroke dynamic behavioral changes take place associated with different levels of recovery. Understanding the biological mechanisms that drive post-stroke recovery is of paramount clinical importance, since such knowledge could provide...
Clinical Studies - Jul 1, 2011 - May 31, 2015
Automatically Closed
Project leader: Kägi Georg
Members: Weder Bruno, Wiest Roland, Slotboom Johannes
Tenere Extension: A multi-center, randomized, parallel-group, rater-blinded study comparing the effectiveness and safety of teriflunomide and interferon beta-1a in patients with relapsing multiple sclerosis
May 1, 2011
Clinical Studies - May 1, 2011 - Dec 31, 2013
Completed
Project leader: Müller Stefanie
Members: Vehoff Jochen, Siebel Philip
A single arm, open-label, multicenter study evaluating the long-term safety and tolerability of 0.5 mg fingolimod (FTY720) administered orally once daily in patients with relapsing forms of multiple sclerosis
Apr 1, 2011A single arm, open-label, multicenter study evaluating the long-term safety and tolerability of 0.5 mg fingolimod (FTY720) administered orally once daily in patients with relapsing forms of multiple sclerosis Study: FTY720 - 2399
Clinical Studies - Apr 1, 2011 - Feb 28, 2012
Completed
Project leader: Müller Stefanie