Projects
Search from 1157 projects:
1157 Project(s)
Intratumoral injection of IP-001 following thermal ablation in patients with advanced solid tumors. A multicenter phase Ib/IIa trial with expansion cohorts in melanoma and soft tissue sarcoma patients
Oct 7, 2020Diese Studie untersucht die Sicherheit und erste Wirksamkeit einer immunstimulierenden intratumoralen Laser-Wärmetherapie in Kombination mit dem Studienmedikament IP-001, welches in den Tumor injiziert wird. Alle Patienten in dieser Studie erhalten d...
Clinical Studies - Oct 7, 2020 - Dec 31, 2024
Ongoing
Project leader: Jörger Markus
Members: Wittwer Yvonne, Quinter Janine
A phase II, open label, randomized, parallel arm study of
Oct 2, 2020Study of efficacy and safety of NIS793 (anti-TGFbeta antibody) with and without spartalizumab (anti-PD-1 antibody) in combination with SOC chemotherapy in first-line metastatic pancreatic ductal adenocarcinoma (mPDAC)
Clinical Studies - Oct 2, 2020 - Aug 29, 2021
Automatically Closed
Project leader: Horber Daniel
Members: Bickel Angelika, Weisshaupt Christian
Evaluation of InterStim Micro System Performance and Safety (ELITE) to Confirm Long-Term Outcomes
Oct 1, 2020The indications under investigation are overactive bladder, fecal incontinence, and non-obstructive urinary retention. Refer to geography-specific labeling for additional details on indications. There are no investigational devices used in this s...
Clinical Studies - Oct 1, 2020 - Apr 30, 2024
Completed
Project leader: Marti Lukas
Members: Beutner Ulrich, Bischofberger Stephan, Widmann Bernhard
APD334-206 Etrasimod
Oct 1, 2020A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Etrasimod in Adult Subjects with Eosinophilic Esophagitis
Clinical Studies - Oct 1, 2020 - Dec 1, 2022
Completed
Project leader: Brand Stephan, Smolders Jolijn
SwissSCAD
Oct 1, 2020The primary aim is to gather observational data from consecutive SCAD patients in Switzerland, in order to establish a National Swiss Registry (SwissSCAD). SCAD is a poorly understood condition, affecting young patients and is associated with major...
Clinical Studies - Oct 1, 2020 - Dec 31, 2030
Ongoing
Project leader: Rickli Hans
Members: Schneider Irene
Komplikationsrate von peripher verabreichtem Noradrenalin in der Anästhesie
Oct 1, 2020Hintergrund: Während einer Anästhesie wird aufgrund der durch die Anästhetika verursachten Vasodilatation zur Aufrechterhaltung eines adäquaten Blutdrucks oft eine Therapie mit Vasopressoren notwendig. Dafür eignet sich die kontinuierliche Gabe von N...
Clinical Studies - Oct 1, 2020 - Sep 30, 2021
Automatically Closed
Project leader: Filipovic Miodrag
Members: Schmucki Renate
COugh During and after acute EXacerbation of chronic obstructive pulmonary disease (CODEX) study
Sep 8, 2020
Clinical Studies - Sep 8, 2020 - Jul 1, 2021
Automatically Closed
Project leader: Rassouli Frank
Members: Brutsche Martin, Barata Filipe, Cleres David
PIONEER REAL
Sep 1, 2020The primary objective is to investigate the glycaemic control in adult patients with type 2 diabetes (T2D) who have not previously been treated with injectable glucose-lowering medication and who initiate treatment with oral semaglutide according to...
Clinical Studies - Sep 1, 2020 - Sep 1, 2022
Automatically Closed
Project leader: Bilz Stefan
Members: Drescher Tilman, Grillmayr Victoria, Räss Andrea
TRIAGE
Sep 1, 2020A randomised, Double-Blind, Placebo-Controlled, Dose-Finding Phase IIb Study to assess the efficacy and safety of orally administered Epeleuton in Patients with Hypertriglyceridemia and Typ 2 Diabetes. Short Title: TRIglyceride And Glucose contro...
Clinical Studies - Sep 1, 2020 - Aug 31, 2021
Automatically Closed
Project leader: Bilz Stefan
Members: Veraguth Katja, Quarella Marino, Räss Andrea, Grillmayr Victoria
Biogen c9ORF 245AS102
Sep 1, 2020Eine Verlängerungsstudie zur Beurteilung von Langzeitsicherheit, Verträglichkeit, Pharmakokinetik und Wirkung auf das Fortschreiten der Erkrankung von BIIB078 bei zuvor behandelten Erwachsenen mit C9ORF72-assoziierter amyotropher Lateralsklerose
Clinical Studies - Sep 1, 2020 - Dec 31, 2024
Completed
Project leader: Weber Markus
SURPRISE+: SURveillance of infectious diseases among health PRofessionals In SwitzErland – a longitudinal, multicentre cohort
Sep 1, 2020In this multicentre healthcare worker cohort, we are studying risk factors, humoral immunity and long COVID symptoms in healthcare workers from 9 healthcare systems from Eastern and Northern Switzerland.
Healthcare Research - Sep 1, 2020 - Dec 31, 2023
Automatically Closed
Project leader: Kohler Philipp
Outcome von Patienten mit Kopf-Hals-Malignomen in der Hals-Nasen-Ohrenklinik am Kantonsspital St.Gallen
Sep 1, 2020
Register - Sep 1, 2020 - Feb 28, 2023
Automatically Closed
Project leader: Kiessling Si-Young, Stöckli Sandro
Members: Stanossek Yves
I4V-MC-JAIM
Aug 12, 2020a phase 3, double-blind, multicenter study of evaluate the long-term safety and efficacy of baricitinib in patients with SLE.
Clinical Studies - Aug 12, 2020 - Aug 12, 2022
Completed
Project leader: Rubbert-Roth Andrea
Members: Peischl Riana, Bartz-Batliner Mira
SAKK 23/18 Vision I
Aug 11, 2020Neoadjuvant chemotherapy (NAC), initially indicated to downstage tumors to achieve the option of breast conserv-ing surgery, has lately become common practice in the primary treatment of breast cancer. The use of modern NAC regimens lead to a complet...
Clinical Studies - Aug 11, 2020 - Dec 18, 2024
Ongoing
SAKK 23/18 Vision I
Aug 11, 2020Neoadjuvant chemotherapy (NAC), initially indicated to downstage tumors to achieve the option of breast conserv-ing surgery, has lately become common practice in the primary treatment of breast cancer. The use of modern NAC regimens lead to a complet...
Clinical Studies - Aug 11, 2020 - Dec 18, 2024
Ongoing
Vacuum assisted biopsy Immediately before Surgery as an Intra- or pre-Operative surrogate for patient response to Neoadjuvant chemotherapy for breast cancer (VISION I) A multicenter prospective feasibility trial
Aug 11, 2020Manche Patientinnen und Patienten mit Brustkrebs erhalten vor der Tumoroperation eine Chemotherapie, um den Tumor zu verkleinern. Manchmal wirkt diese Chemotherapie so gut, dass der Tumor nach der Chemotherapie mit bildgebenden Verfahren nicht mehr n...
Clinical Studies - Aug 11, 2020 - Dec 31, 2024
Ongoing
Project leader: Strub Christine
Members: Sennhauser Andrina, Quinter Janine
PH-L19IL2TNFNMSC-04/19 A phase II study of intratumoral administration of L19IL2/L19TNF in non-melanoma skin cancer patients with presence of injectable lesions
Aug 2, 2020
Clinical Studies - Aug 2, 2020 - Jan 25, 2030
Ongoing
Project leader: Flatz Lukas
CRiPSI/CRiPSI-X: Covid-19 Risk Prediction in Swiss ICUs-Trial/Extension
Aug 1, 2020Outcome of patients with critical Covid-19 varies. We study risk of and predictors for poor outcome in adult patients with Covid-19 admitted to ICU in a multicenter study. In addition, we assess the prevalence of, risk factors for and mechanisms invo...
Clinical Studies - Aug 1, 2020 - Aug 31, 2022
Automatically Closed
Project leader: Albrich Werner
Members: Von Mering Christian, O'Mahony Liam, Cerny Andreas, Suh Noémie, El Baz Yassir, Dietrich Tobias, Fischer Tim, Felbecker Ansgar, Göhl-Freyn Kristina, Germann Nicolas, Schmid Dagmar, Kahlert Christian, Frischknecht Manuel, Filipovic Miodrag, Brutsche Martin, Pietsch Urs, Kleger Gian-Reto, Bochud Pierre-Yves
Abbvie UPHOLD P20-095 SLEERA
Aug 1, 2020Upadacitinib treatment patterns, achievement of treatment targets and maintenance of response in moderate to severe Rheumatoid Arthritis patients in real-world practice
Clinical Studies - Aug 1, 2020 - Oct 31, 2023
Automatically Closed
Project leader: Rubbert-Roth Andrea
Members: Bartz-Batliner Mira, Hutz Carina Liane, Peischl Riana, Peischl Shirin, Schmiedeberg Kristin
ESSENCE Study
Aug 1, 2020
Clinical Studies - Aug 1, 2020 - Dec 31, 2029
Ongoing
Project leader: Bilz Stefan
Members: Semela David, Räss Andrea, Stillhard Roman