Bereich
Institut für Immunbiologie
IMMBIO · Dept. Direktion
Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8 T cells
Cupovic J, Klenerman P, Engeler D, Krebs P, Scandella E, Oxenius A, Flatz L, Provine N, De Martin A, Cheng H, Lütge M, Colston J, Onder L, Ring S, Ludewig B. Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8 T cells. Nat Immunol 2021; 22:1042-1051.
15.07.2021Adenovirus vector vaccination reprograms pulmonary fibroblastic niches to support protective inflating memory CD8 T cells
15.07.2021Nat Immunol 2021; 22:1042-1051
Cupovic Jovana, Klenerman Paul, Engeler Daniel, Krebs Philippe, Scandella Elke, Oxenius Annette, Flatz Lukas, Provine Nicholas M, De Martin Angelina, Cheng Hung-Wei, Lütge Mechthild, Colston Julia M, Onder Lucas, Ring Sandra, Ludewig Burkhard
Anti-SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis
Rubbert-Roth A, Vuilleumier N, Ludewig B, Schmiedeberg K, Haller C, von Kempis J. Anti-SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis. Lancet Rheumatol 2021; 3:e470-e472.
08.06.2021Anti-SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis
08.06.2021Lancet Rheumatol 2021; 3:e470-e472
Rubbert-Roth Andrea, Vuilleumier Nicolas, Ludewig Burkhard, Schmiedeberg Kristin, Haller Christoph, von Kempis Johannes
Differentiation and activation of fibroblastic reticular cells
Lütge M, Pikor N, Ludewig B. Differentiation and activation of fibroblastic reticular cells. Immunol Rev 2021; 302:32-46.
27.05.2021Differentiation and activation of fibroblastic reticular cells
27.05.2021Immunol Rev 2021; 302:32-46
Lütge Mechthild, Pikor Natalia, Ludewig Burkhard
Preexisting and Post-COVID-19 Immune Responses to SARS-CoV-2 in Patients with Cancer
Bilich T, Flatz L, Held S, Brossart P, Märklin M, Wagner P, Erne E, Klein R, Rammensee H, Salih H, Berner F, Wacker M, Roerden M, Maringer Y, Nelde A, Heitmann J, Dubbelaar M, Peter A, Hörber S, Bauer J, Rieth J, Walz J. Preexisting and Post-COVID-19 Immune Responses to SARS-CoV-2 in Patients with Cancer. Cancer Discov 2021; 11:1982-1995.
19.05.2021Preexisting and Post-COVID-19 Immune Responses to SARS-CoV-2 in Patients with Cancer
19.05.2021Cancer Discov 2021; 11:1982-1995
Bilich Tatjana, Flatz Lukas, Held Stefanie, Brossart Peter, Märklin Melanie, Wagner Philipp, Erne Eva, Klein Reinhild, Rammensee Hans-Georg, Salih Helmut R, Berner Fiamma, Wacker Marcel, Roerden Malte, Maringer Yacine, Nelde Annika, Heitmann Jonas S, Dubbelaar Marissa L, Peter Andreas, Hörber Sebastian, Bauer Jens, Rieth Jonas, Walz Juliane S
Fibroblasts as immune regulators in infection, inflammation and cancer
Davidson S, Coles M, Thomas T, Kollias G, Ludewig B, Turley S, Brenner M, Buckley C. Fibroblasts as immune regulators in infection, inflammation and cancer. Nat Rev Immunol 2021; 21:704-717.
28.04.2021Fibroblasts as immune regulators in infection, inflammation and cancer
28.04.2021Nat Rev Immunol 2021; 21:704-717
Davidson Sarah, Coles Mark, Thomas Tom, Kollias George, Ludewig Burkhard, Turley Shannon, Brenner Michael, Buckley Christopher D
Insights into coronavirus immunity taught by the murine coronavirus
Grabherr S, Ludewig B, Pikor N. Insights into coronavirus immunity taught by the murine coronavirus. Eur J Immunol 2021; 51:1062-1070.
22.03.2021Insights into coronavirus immunity taught by the murine coronavirus
22.03.2021Eur J Immunol 2021; 51:1062-1070
Grabherr Sarah, Ludewig Burkhard, Pikor Natalia
Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity
Prados A, Ludewig B, Koliaraki V, Pérez Shibayama C, Gil Cruz C, Lütge M, Mörbe U, Cheng H, Onder L, Kollias G. Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity. Nat Immunol 2021; 22:510-519.
11.03.2021Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity
11.03.2021Nat Immunol 2021; 22:510-519
Prados Alejandro, Ludewig Burkhard, Koliaraki Vasiliki, Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Lütge Mechthild, Mörbe Urs, Cheng Hung-Wei, Onder Lucas, Kollias George
The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis
Seidenberg J, Stellato M, Hukara A, Ludewig B, Klingel K, Distler O, Błyszczuk P, Kania G. The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis. Int J Mol Sci 2021; 22
13.02.2021The AP-1 Transcription Factor Fosl-2 Regulates Autophagy in Cardiac Fibroblasts during Myocardial Fibrogenesis
13.02.2021Int J Mol Sci 2021; 22
Seidenberg Jemima, Stellato Mara, Hukara Amela, Ludewig Burkhard, Klingel Karin, Distler Oliver, Błyszczuk Przemysław, Kania Gabriela
Recombinant lymphocytic choriomeningitis virus-based vaccine vector protects type I interferon receptor deficient mice from viral challenge
Królik M, Csepregi L, Hartmann F, Engetschwiler C, Flatz L. Recombinant lymphocytic choriomeningitis virus-based vaccine vector protects type I interferon receptor deficient mice from viral challenge. Vaccine 2021; 39:1257-1264.
29.01.2021Recombinant lymphocytic choriomeningitis virus-based vaccine vector protects type I interferon receptor deficient mice from viral challenge
29.01.2021Vaccine 2021; 39:1257-1264
Królik Michał Wojciech, Csepregi Lucia, Hartmann Fabienne, Engetschwiler Céline, Flatz Lukas
Development and Immunological Function of Lymph Node Stromal Cells
Pikor N, Cheng H, Onder L, Ludewig B. Development and Immunological Function of Lymph Node Stromal Cells. J Immunol 2021; 206:257-263.
15.01.2021Development and Immunological Function of Lymph Node Stromal Cells
15.01.2021J Immunol 2021; 206:257-263
Pikor Natalia, Cheng Hung-Wei, Onder Lucas, Ludewig Burkhard
PPARγ is essential for the development of bone marrow erythroblastic island macrophages and splenic red pulp macrophages
Okreglicka K, Schneider C, Nielsen P, Ludewig B, Kurrer M, Feng Q, Onder L, Pohlmeier L, Iten I, Kopf M. PPARγ is essential for the development of bone marrow erythroblastic island macrophages and splenic red pulp macrophages. J Exp Med 2021; 218
03.01.2021PPARγ is essential for the development of bone marrow erythroblastic island macrophages and splenic red pulp macrophages
03.01.2021J Exp Med 2021; 218
Okreglicka Katarzyna, Schneider Christoph, Nielsen Peter, Ludewig Burkhard, Kurrer Michael, Feng Qian, Onder Lucas, Pohlmeier Lea, Iten Irina, Kopf Manfred
Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy
Bochem J, Meier F, Terheyden P, Königsrainer A, Garbe C, Flatz L, Pawelec G, Eigentler T, Löffler M, Weide B, Niessner H, Sinnberg T, Zelba H, Spreuer J, Amaral T, Gaissler A, Pop O, Thiel K, Yurttas C, Soffel D, Forchhammer S, Wistuba-Hamprecht K. Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy. J Immunother Cancer 2021; 9
01.01.2021Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy
01.01.2021J Immunother Cancer 2021; 9
Bochem Jonas, Meier Friedegund, Terheyden Patrick, Königsrainer Alfred, Garbe Claus, Flatz Lukas, Pawelec Graham, Eigentler Thomas K, Löffler Markus W, Weide Benjamin, Niessner Heike, Sinnberg Tobias, Zelba Henning, Spreuer Janine, Amaral Teresa, Gaissler Andrea, Pop Oltin, Thiel Karolin, Yurttas Can, Soffel Daniel, Forchhammer Stephan, Wistuba-Hamprecht Kilian
Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues
Guendel F, Hehlgans T, Waisman A, Becher B, Giannou A, Brachs S, Ebert K, Tanriver Y, Ludewig B, Mashreghi M, Kruglov A, Pfeffer K, Herold S, Ruedl C, Kofoed-Branzk M, Gronke K, Tizian C, Witkowski M, Cheng H, Heinz G, Heinrich F, Durek P, Norris P, Ware C, Diefenbach A. Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues. Immunity 2020; 53:1015-1032.e8.
17.11.2020Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues
17.11.2020Immunity 2020; 53:1015-1032.e8
Guendel Fabian, Hehlgans Thomas, Waisman Ari, Becher Burkhard, Giannou Anastasios D, Brachs Sebastian, Ebert Karolina, Tanriver Yakup, Ludewig Burkhard, Mashreghi Mir-Farzin, Kruglov Andrey A, Pfeffer Klaus, Herold Susanne, Ruedl Christiane, Kofoed-Branzk Michael, Gronke Konrad, Tizian Caroline, Witkowski Mario, Cheng Hung-Wei, Heinz Gitta Anne, Heinrich Frederik, Durek Pawel, Norris Paula S, Ware Carl F, Diefenbach Andreas
Author Correction: In vitro virucidal activity of Echinaforce, an Echinacea purpurea preparation, against coronaviruses, including common cold coronavirus 229E and SARS-CoV-2
Signer J, Schoop R, Suter A, Siegrist D, Lenz N, Ackermann-Gäumann R, Ryter S, Züst R, Strasser M, Albrich W, Jonsdottir H, Engler O. Author Correction: In vitro virucidal activity of Echinaforce, an Echinacea purpurea preparation, against coronaviruses, including common cold coronavirus 229E and SARS-CoV-2. Virol J 2020; 17:172.
09.11.2020Author Correction: In vitro virucidal activity of Echinaforce, an Echinacea purpurea preparation, against coronaviruses, including common cold coronavirus 229E and SARS-CoV-2
09.11.2020Virol J 2020; 17:172
Signer Johanna, Schoop Roland, Suter Andreas, Siegrist Denise, Lenz Nicole, Ackermann-Gäumann Rahel, Ryter Sarah, Züst Roland, Strasser Marc, Albrich Werner, Jonsdottir Hulda R, Engler Olivier B
Numbers Game and Immune Geography as Determinants of Coronavirus Pathogenicity
Bocharov G, Casella V, Argilaguet J, Grebennikov D, Güerri-Fernandez R, Ludewig B, Meyerhans A. Numbers Game and Immune Geography as Determinants of Coronavirus Pathogenicity. Front Cell Infect Microbiol 2020; 10:559209.
23.10.2020Numbers Game and Immune Geography as Determinants of Coronavirus Pathogenicity
23.10.2020Front Cell Infect Microbiol 2020; 10:559209
Bocharov Gennady, Casella Valentina, Argilaguet Jordi, Grebennikov Dmitry, Güerri-Fernandez Roberto, Ludewig Burkhard, Meyerhans Andreas
CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8 T Cells
Bald T, Scolyer R, Long G, Wilmott J, Hughes B, Ahern E, Taheri T, Kristiansen G, Geyer M, Hölzel M, Seo E, Batstone M, Landsberg J, Smyth M, Martinet L, Johnston R, Möller A, Nicholson S, Veillette A, Dougall W, Flatz L, Pop O, Dietrich D, Nakamura K, Casey M, Koufariotis L, Li R, Li K, Meza Guzman L, Lima L, Das I, Krumeich S, Stannard K, Corvino D, Sundarrajan A, Aguilera A, Salim N, Jorge M, Quine B, Effern M, Jacquelin S, Madore J, Pearson S, Raghavendra A, Lepletier A, Vari F, Kelly G, Ham S, Braun M. CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8 T Cells. Immunity 2020; 53:805-823.e15.
13.10.2020CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8 T Cells
13.10.2020Immunity 2020; 53:805-823.e15
Bald Tobias, Scolyer Richard A, Long Georgina V, Wilmott James S, Hughes Brett G M, Ahern Elizabeth, Taheri Touraj, Kristiansen Glen, Geyer Matthias, Hölzel Michael, Seo Eun Y, Batstone Martin D, Landsberg Jennifer, Smyth Mark J, Martinet Ludovic, Johnston Robert J, Möller Andreas, Nicholson Sandra E, Veillette André, Dougall William C, Flatz Lukas, Pop Oltin, Dietrich Dimo, Nakamura Kyohei, Casey Mika, Koufariotis Lambros T, Li Rui, Li Kunlun, Meza Guzman Lizeth G, Lima Luize G, Das Indrajit, Krumeich Sophie, Stannard Kimberley, Corvino Dillon, Sundarrajan Ashmitha, Aguilera Amelia Roman, Salim Nazhifah, Jorge Maria Villancanas, Quine Brodie, Effern Maike, Jacquelin Sebastien, Madore Jason, Pearson Sally, Raghavendra Ashwini, Lepletier Ailin, Vari Frank, Kelly Gabrielle, Ham Sunyoung, Braun Matthias
Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8 T Cell Responses
Ring S, Królik M, Hartmann F, Schmidt E, Ali O, Ludewig B, Kochanek S, Flatz L. Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8 T Cell Responses. Mol Ther Oncolytics 2020; 19:179-187.
10.10.2020Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8 T Cell Responses
10.10.2020Mol Ther Oncolytics 2020; 19:179-187
Ring Sandra, Królik Michał Wojciech, Hartmann Fabienne, Schmidt Erika, Ali Omar Hasan, Ludewig Burkhard, Kochanek Stefan, Flatz Lukas
Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells
Pérez Shibayama C, Gil Cruz C, Colston J, Novkovic M, De Martin A, Ring S, Onder L, Cheng H, Lütge M, Islander U, Ludewig B. Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells. Sci Immunol 2020; 5
11.09.2020Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 T cells
11.09.2020Sci Immunol 2020; 5
Pérez Shibayama Christian Ivan, Gil Cruz Cristina, Colston Julia, Novkovic Mario, De Martin Angelina, Ring Sandra, Onder Lucas, Cheng Hung-Wei, Lütge Mechthild, Islander Ulrika, Ludewig Burkhard
In vitro virucidal activity of Echinaforce®, an Echinacea purpurea preparation, against coronaviruses, including common cold coronavirus 229E and SARS-CoV-2
Signer J, Schoop R, Suter A, Siegrist D, Lenz N, Ackermann-Gäumann R, Ryter S, Züst R, Strasser M, Albrich W, Jonsdottir H, Engler O. In vitro virucidal activity of Echinaforce®, an Echinacea purpurea preparation, against coronaviruses, including common cold coronavirus 229E and SARS-CoV-2. Virol J 2020; 17:136.
09.09.2020In vitro virucidal activity of Echinaforce®, an Echinacea purpurea preparation, against coronaviruses, including common cold coronavirus 229E and SARS-CoV-2
09.09.2020Virol J 2020; 17:136
Signer Johanna, Schoop Roland, Suter Andreas, Siegrist Denise, Lenz Nicole, Ackermann-Gäumann Rahel, Ryter Sarah, Züst Roland, Strasser Marc, Albrich Werner, Jonsdottir Hulda R, Engler Olivier B
Molecular, clinicopathological, and immune correlates of LAG3 promoter DNA methylation in melanoma
Fröhlich A, Ring S, Golletz C, Pietsch T, Strieth S, Brossart P, Gielen G, Kristiansen G, Bootz F, Landsberg J, Flatz L, Hoffmann F, Sirokay J, Fietz S, Vogt T, Dietrich J, Zarbl R, Florin M, Kuster P, Saavedra G, Valladolid S, Dietrich D. Molecular, clinicopathological, and immune correlates of LAG3 promoter DNA methylation in melanoma. EBioMedicine 2020; 59:102962.
30.08.2020Molecular, clinicopathological, and immune correlates of LAG3 promoter DNA methylation in melanoma
30.08.2020EBioMedicine 2020; 59:102962
Fröhlich Anne, Ring Sandra, Golletz Carsten, Pietsch Torsten, Strieth Sebastian, Brossart Peter, Gielen Gerrit H, Kristiansen Glen, Bootz Friedrich, Landsberg Jennifer, Flatz Lukas, Hoffmann Friederike, Sirokay Judith, Fietz Simon, Vogt Timo J, Dietrich Jörn, Zarbl Romina, Florin Mike, Kuster Pia, Saavedra Gonzalo, Valladolid Susana Ramírez, Dietrich Dimo