Cell-Free Oxyhemoglobin in Cerebrospinal Fluid After Aneurysmal Subarachnoid Hemorrhage: Biomarker and Potential Therapeutic Target.

Publikation

Cell-Free Oxyhemoglobin in Cerebrospinal Fluid After Aneurysmal Subarachnoid Hemorrhage: Biomarker and Potential Therapeutic Target.

Wissenschaftlicher Artikel/Review - 27.08.2018

Hugelshofer Michael, Sikorski Christopher M, Seule Martin, Deuel Jeremy, Muroi Carl I, Seboek Martina, Akeret Kevin, Buzzi Raphael, Regli Luca, Schaer Dominik J, Keller Emanuela

Zitation

Hugelshofer M, Sikorski C, Seule M, Deuel J, Muroi C, Seboek M, Akeret K, Buzzi R, Regli L, Schaer D, Keller E. Cell-Free Oxyhemoglobin in Cerebrospinal Fluid After Aneurysmal Subarachnoid Hemorrhage: Biomarker and Potential Therapeutic Target. World Neurosurg 2018; 120:e660-e666.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

World Neurosurg 2018; 120

Veröffentlichungsdatum

27.08.2018

eISSN (Online)

1878-8769

Seiten

e660-e666

Kurzbeschreibung/Zielsetzung

Aneurysmal subarachnoid hemorrhage (aSAH) is often complicated by the occurrence of delayed ischemic neurologic deficits (DIND), which impairs the clinical outcome of patients. The release of oxyhemoglobin (oxyHb) from lysing erythrocytes into cerebrospinal fluid (CSF) may critically contribute to the development of DIND.