Microporous ß-Tricalcium Phosphate (TCP) - A Delivery Vehicle of Growth Factors and Drugs - Publikation

Publikation

Microporous ß-Tricalcium Phosphate (TCP) - A Delivery Vehicle of Growth Factors and Drugs

Wissenschaftlicher Artikel/Review - 01.11.2013

Bernstein Anke, Suedkamp Norbert P, Mayr Hermann O, Kissling Steffen, Seidenstuecker Michael

Bereiche

Rechtsmedizin

Kontakt

Steffen Kissling

Zitation

Bernstein A, Suedkamp N, Mayr H, Kissling S, Seidenstuecker M. Microporous ß-Tricalcium Phosphate (TCP) - A Delivery Vehicle of Growth Factors and Drugs. Key Engineering Materials 2013:93-96.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Key Engineering Materials 2013

Veröffentlichungsdatum

01.11.2013

Seiten

93-96

Kurzbeschreibung/Zielsetzung

In this present work we could show that a microporous β-TCP ceramic with interconnected porosity and 5 μm median pore diameter is a useful delivery vehicle for drugs and growth factors. However, it is necessary to combine the ceramics with degradable biopolymers, like hydrogels for retarded release. So the drug release could be increased by the factor 7 from 3 up to 21 days with concentrations having an antimicrobial activity. Concerning the growth factor, the release period was prolonged significantly.