Microporous ß-Tricalcium Phosphate (TCP) - A Delivery Vehicle of Growth Factors and Drugs - Publication

Publication

Microporous ß-Tricalcium Phosphate (TCP) - A Delivery Vehicle of Growth Factors and Drugs

Journal Paper/Review - Nov 1, 2013

Bernstein Anke, Suedkamp Norbert P, Mayr Hermann O, Kissling Steffen, Seidenstuecker Michael

Units

Rechtsmedizin

Contact

Steffen Kissling

Citation

Bernstein A, Suedkamp N, Mayr H, Kissling S, Seidenstuecker M. Microporous ß-Tricalcium Phosphate (TCP) - A Delivery Vehicle of Growth Factors and Drugs. Key Engineering Materials 2013:93-96.

Type

Journal Paper/Review (English)

Journal

Key Engineering Materials 2013

Publication Date

Nov 1, 2013

Pages

93-96

Brief description/objective

In this present work we could show that a microporous β-TCP ceramic with interconnected porosity and 5 μm median pore diameter is a useful delivery vehicle for drugs and growth factors. However, it is necessary to combine the ceramics with degradable biopolymers, like hydrogels for retarded release. So the drug release could be increased by the factor 7 from 3 up to 21 days with concentrations having an antimicrobial activity. Concerning the growth factor, the release period was prolonged significantly.