Publikation

Reactive macrophage activation syndrome: a simple screening strategy and its potential in early treatment initiation

Wissenschaftlicher Artikel/Review - 04.05.2002

Bereiche
PubMed
DOI

Zitation
Emmenegger U, Spaeth P, Cerny A, Cottagnoud P, Semela D, Bihl F, Fux C, Frey U, Reimers A, Neftel K. Reactive macrophage activation syndrome: a simple screening strategy and its potential in early treatment initiation. Swiss Med Wkly 2002; 132:230-6.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Swiss Med Wkly 2002; 132
Veröffentlichungsdatum
04.05.2002
ISSN (Druck)
1424-7860
Seiten
230-6
Kurzbeschreibung/Zielsetzung

starting treatment of reactive macrophage activation syndromes as early as possible (rMAS, haemophagocytic lymphohistiocytosis), e.g., with intravenous immunoglobulins (IVIG), seems to be essential for optimal outcome. However, there is no diagnostic gold standard which reliably indicates need for early treatment. We used a simple screening strategy consisting of serum ferritin measurements and/or morphological assessment of haemophagocytosis and compared the studied patient population with published series.