Publikation
Reactive macrophage activation syndrome: a simple screening strategy and its potential in early treatment initiation
Wissenschaftlicher Artikel/Review - 04.05.2002
Emmenegger U, Spaeth P J, Cerny A, Cottagnoud P, Semela David, Bihl F, Fux Ch, Frey U, Reimers A, Neftel Klaus A
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starting treatment of reactive macrophage activation syndromes as early as possible (rMAS, haemophagocytic lymphohistiocytosis), e.g., with intravenous immunoglobulins (IVIG), seems to be essential for optimal outcome. However, there is no diagnostic gold standard which reliably indicates need for early treatment. We used a simple screening strategy consisting of serum ferritin measurements and/or morphological assessment of haemophagocytosis and compared the studied patient population with published series.