Publikation
Receptor-mediated targeting of cathepsins in professional antigen presenting cells
Wissenschaftlicher Artikel/Review - 01.01.2009
Hillaert Ulrik, Driessen Christoph, van der Marel Gijsbert A, Ossendorp Ferry, Van Calenbergh Serge, Kuiper Johan, Habets Kim L L, Saragliadis Anastasios, Saragliadis Athanasios, Florea Bogdan I, Verdoes Martijn, Overkleeft Hermen S
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Tag for professionals: A fluorescently tagged clustered mannoside DCG-04 analogue (see structure) is designed and synthesized using a modular approach. Uptake of the probe in professional antigen presenting cells and subsequent labeling of cathepsins proceeded in a mannose-receptor dependent manner.