Publikation

Receptor-mediated targeting of cathepsins in professional antigen presenting cells

Wissenschaftlicher Artikel/Review - 01.01.2009

Bereiche
PubMed
DOI

Zitation
Hillaert U, Driessen C, van der Marel G, Ossendorp F, Van Calenbergh S, Kuiper J, Habets K, Saragliadis A, Saragliadis A, Florea B, Verdoes M, Overkleeft H. Receptor-mediated targeting of cathepsins in professional antigen presenting cells. Angewandte Chemie (International ed. in English) 2009; 48:1629-32.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Angewandte Chemie (International ed. in English) 2009; 48
Veröffentlichungsdatum
01.01.2009
eISSN (Online)
1521-3773
Seiten
1629-32
Kurzbeschreibung/Zielsetzung

Tag for professionals: A fluorescently tagged clustered mannoside DCG-04 analogue (see structure) is designed and synthesized using a modular approach. Uptake of the probe in professional antigen presenting cells and subsequent labeling of cathepsins proceeded in a mannose-receptor dependent manner.