Publikation
[HIV infection, fever and cholestasis]
Wissenschaftlicher Artikel/Review - 14.06.1994
Giezendanner S, Zala G, Jost J, Greminger Peter, Meyenberger Christa
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PubMed
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Kurzbeschreibung/Zielsetzung
A 35-year-old Swiss woman with AIDS experienced fever, jaundice and cough. Laboratory evaluation revealed signs of an infection and cholestasis. The examination by ultrasound showed thickening of the intra- and extrahepatic bile ducts and gallbladder wall, without dilatation or stones. Endoscopic retrograde cholangiography demonstrated diffuse sclerosing cholangitis like lesions in the biliary tract and confirmed the diagnosis of a HIV related cholangiopathy. The cause was a cytomegalovirus infection as shown by liver biopsy with detection of cytomegalovirus early antigen. The treatment with ganciclovir was of some efficacy with improvement of jaundice.