Publication
[HIV infection, fever and cholestasis]
Journal Paper/Review - Jun 14, 1994
Giezendanner S, Zala G, Jost J, Greminger Peter, Meyenberger Christa
Units
PubMed
Citation
Type
Journal
Publication Date
Issn Print
Pages
Brief description/objective
A 35-year-old Swiss woman with AIDS experienced fever, jaundice and cough. Laboratory evaluation revealed signs of an infection and cholestasis. The examination by ultrasound showed thickening of the intra- and extrahepatic bile ducts and gallbladder wall, without dilatation or stones. Endoscopic retrograde cholangiography demonstrated diffuse sclerosing cholangitis like lesions in the biliary tract and confirmed the diagnosis of a HIV related cholangiopathy. The cause was a cytomegalovirus infection as shown by liver biopsy with detection of cytomegalovirus early antigen. The treatment with ganciclovir was of some efficacy with improvement of jaundice.