Glucocorticoids versus glucocorticoids plus cyclophosphamide in eosinophilic granulomatosis with polyangiitis with poor-prognosis factors.

Publikation

Glucocorticoids versus glucocorticoids plus cyclophosphamide in eosinophilic granulomatosis with polyangiitis with poor-prognosis factors.

Wissenschaftlicher Artikel/Review - 16.11.2024

Sorin Boris, Papo Matthias, Sinico Renato Alberto, Teixeira Vítor Silvestre, Venhoff Nils, Urban Maria Letizia, Iudici Michele, Mahrhold Juliane, Locatelli Francesco, Cassone Giulia, Schiavon Franco, Seeliger Benjamin, Neumann Thomas, Feder Claudia, Kroegel Claus, Groh Matthieu, Marvisi Chiara, Samson Maxime, Barba Thomas, Jayne David R.W., Troilo Arianna, Thiel Jens, Hellmich Bernhard, Monti Sara, Montecucco Carlomaurizio, Salvarani Carlo, Kahn Jean-Emmanuel, Bonnotte Bernard, Durel Cécile-Audrey, Puéchal Xavier, Mouthon Luc, Guillevin Loic, Emmi Giacomo, Vaglio Augusto, Porcher Raphael, Terrier Benjamin

Zitation

Sorin B, Papo M, Sinico R, Teixeira V, Venhoff N, Urban M, Iudici M, Mahrhold J, Locatelli F, Cassone G, Schiavon F, Seeliger B, Neumann T, Feder C, Kroegel C, Groh M, Marvisi C, Samson M, Barba T, Jayne D, Troilo A, Thiel J, Hellmich B, Monti S, Montecucco C, Salvarani C, Kahn J, Bonnotte B, Durel C, Puéchal X, Mouthon L, Guillevin L, Emmi G, Vaglio A, Porcher R, Terrier B. Glucocorticoids versus glucocorticoids plus cyclophosphamide in eosinophilic granulomatosis with polyangiitis with poor-prognosis factors. J Autoimmun 2024; 149:103338.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

J Autoimmun 2024; 149

Veröffentlichungsdatum

16.11.2024

eISSN (Online)

1095-9157

Seiten

103338

Kurzbeschreibung/Zielsetzung

Current guidelines suggest treating poor-prognosis eosinophilic granulomatosis with polyangiitis (EGPA) with a combination of glucocorticoids (GCs) plus cyclophosphamide (CYC). However, there is little data to support the need for the addition of CYC. The objective of this study was to compare GCs plus CYC to GCs alone as induction therapy in poor-prognosis EGPA.