Intracranial hemorrhage, outcome, and mortality after intra-arterial therapy for acute ischemic stroke in patients under oral anticoagulants.

Publikation

Intracranial hemorrhage, outcome, and mortality after intra-arterial therapy for acute ischemic stroke in patients under oral anticoagulants.

Wissenschaftlicher Artikel/Review - 06.10.2011

De Marchis Gian Marco, Jung Simon, Colucci Giuseppe, Meier Niklaus, Fischer Urs, Weck Anja, Mono Marie-Luise, Galimanis Aekaterini, Mattle Heinrich Paul, Schroth Gerhard, Gralla Jan, Arnold Marcel, Brekenfeld Caspar

Zitation

De Marchis G, Jung S, Colucci G, Meier N, Fischer U, Weck A, Mono M, Galimanis A, Mattle H, Schroth G, Gralla J, Arnold M, Brekenfeld C. Intracranial hemorrhage, outcome, and mortality after intra-arterial therapy for acute ischemic stroke in patients under oral anticoagulants. Stroke 2011; 42:3061-6.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Stroke 2011; 42

Veröffentlichungsdatum

06.10.2011

eISSN (Online)

1524-4628

Seiten

3061-6

Kurzbeschreibung/Zielsetzung

Use of intravenous tissue-type plasminogen activator (IV tPA) for acute ischemic stroke is restricted to patients with an international normalized ratio (INR) less than 1.7. However, a recent study showed increased risk of symptomatic intracranial hemorrhage after IV tPA use in patients with oral anticoagulants (OAC) even with an INR less than 1.7. The present study assessed the risk of symptomatic intracranial hemorrhage, clinical outcome, and mortality after intra-arterial therapy (IAT) in patients with and without previous use of OAC.