Renal Function and Body Mass Index Contribute to Serum Neurofilament Light Chain Levels in Elderly Patients With Atrial Fibrillation.

Publikation

Renal Function and Body Mass Index Contribute to Serum Neurofilament Light Chain Levels in Elderly Patients With Atrial Fibrillation.

Wissenschaftlicher Artikel/Review - 14.04.2022

Polymeris Alexandros A, Helfenstein Fabrice, Benkert Pascal, Aeschbacher Stefanie, Leppert David, Coslovsky Michael, Willemse Eline, Schaedelin Sabine A, Blum Manuel R, Rodondi Nicolas, Reichlin Tobias, Moschovitis Giorgio, Wuerfel Jens, De Marchis Gian Marco, Engelter Stefan T, Lyrer Philippe A, Conen David, Kühne Michael, Osswald Stefan, Bonati Leo H, Kuhle Jens, Swiss-AF investigators

Zitation

Polymeris A, Helfenstein F, Benkert P, Aeschbacher S, Leppert D, Coslovsky M, Willemse E, Schaedelin S, Blum M, Rodondi N, Reichlin T, Moschovitis G, Wuerfel J, De Marchis G, Engelter S, Lyrer P, Conen D, Kühne M, Osswald S, Bonati L, Kuhle J, Swiss-AF investigators. Renal Function and Body Mass Index Contribute to Serum Neurofilament Light Chain Levels in Elderly Patients With Atrial Fibrillation. Front Neurosci 2022; 16:819010.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Front Neurosci 2022; 16

Veröffentlichungsdatum

14.04.2022

ISSN (Druck)

1662-4548

Seiten

819010

Kurzbeschreibung/Zielsetzung

Serum neurofilament light chain (sNfL) is increasingly used as a neuroaxonal injury biomarker in the elderly. Besides age, little is known about how other physiological factors like renal function and body mass index (BMI) alter its levels. Here, we investigated the association of estimated glomerular filtration rate (eGFR) and BMI with sNfL in a large sample of elderly patients with atrial fibrillation (AF).