Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial.

Publikation

Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial.

Wissenschaftlicher Artikel/Review - 23.05.2022

Darie Andrei M, Khanna Nina, Jahn Kathleen, Osthoff Michael, Bassetti Stefano, Osthoff Mirjam, Schumann Desiree M, Albrich Werner, Hirsch Hans, Brutsche Martin, Grize Leticia, Tamm Michael, Stolz Daiana

Zitation

Darie A, Khanna N, Jahn K, Osthoff M, Bassetti S, Osthoff M, Schumann D, Albrich W, Hirsch H, Brutsche M, Grize L, Tamm M, Stolz D. Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial. Lancet Respir Med 2022; 10:877-887.

Art

Wissenschaftlicher Artikel/Review (Englisch)

Zeitschrift

Lancet Respir Med 2022; 10

Veröffentlichungsdatum

23.05.2022

eISSN (Online)

2213-2619

Seiten

877-887

Kurzbeschreibung/Zielsetzung

PCR-based testing has transformed the management of suspected respiratory viral infections. We aimed to determine whether multiplex bacterial PCR of bronchoalveolar lavage fluid aids antibiotic stewardship in patients with pneumonia.