Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial.

Publication

Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial.

Journal Paper/Review - May 23, 2022

Darie Andrei M, Khanna Nina, Jahn Kathleen, Osthoff Michael, Bassetti Stefano, Osthoff Mirjam, Schumann Desiree M, Albrich Werner, Hirsch Hans, Brutsche Martin, Grize Leticia, Tamm Michael, Stolz Daiana

Citation

Darie A, Khanna N, Jahn K, Osthoff M, Bassetti S, Osthoff M, Schumann D, Albrich W, Hirsch H, Brutsche M, Grize L, Tamm M, Stolz D. Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial. Lancet Respir Med 2022; 10:877-887.

Type

Journal Paper/Review (English)

Journal

Lancet Respir Med 2022; 10

Publication Date

May 23, 2022

Issn Electronic

2213-2619

Pages

877-887

Brief description/objective

PCR-based testing has transformed the management of suspected respiratory viral infections. We aimed to determine whether multiplex bacterial PCR of bronchoalveolar lavage fluid aids antibiotic stewardship in patients with pneumonia.