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Current status and future outlooks on therapeutic drug monitoring of fluorouracil.
Wissenschaftlicher Artikel/Review - 24.01.2022
Schmulenson Eduard, Zimmermann Nigina, Mikus Gerd, Jörger Markus, Jaehde Ulrich
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Therapeutic drug monitoring (TDM) of the anticancer drug fluorouracil (5FU) as a method to support dose adjustments has been researched and discussed extensively. Despite manifold evidence of the advantages of 5FU-TDM, traditional body surface area (BSA)-guided dosing is still widely applied.