Publication
Current status and future outlooks on therapeutic drug monitoring of fluorouracil.
Journal Paper/Review - Jan 24, 2022
Schmulenson Eduard, Zimmermann Nigina, Mikus Gerd, Jörger Markus, Jaehde Ulrich
Units
PubMed
Doi
Contact
Citation
Schmulenson E, Zimmermann N, Mikus G, Jörger M, Jaehde U. Current status and future outlooks on therapeutic drug monitoring of fluorouracil. Expert Opin Drug Metab Toxicol 2022; 17:1407-1422.
Type
Journal Paper/Review (English)
Journal
Expert Opin Drug Metab Toxicol 2022; 17
Publication Date
Jan 24, 2022
Issn Electronic
1744-7607
Pages
1407-1422
Brief description/objective
Therapeutic drug monitoring (TDM) of the anticancer drug fluorouracil (5FU) as a method to support dose adjustments has been researched and discussed extensively. Despite manifold evidence of the advantages of 5FU-TDM, traditional body surface area (BSA)-guided dosing is still widely applied.