Publikation

Parameters of the Lyman Model for Calculation of Normal-Tissue Complication Probability: A Systematic Literature Review.

Wissenschaftlicher Artikel/Review - 24.08.2022

Bereiche
PubMed
DOI
Kontakt

Zitation
Dennstädt F, Medová M, Putora P, Glatzer M. Parameters of the Lyman Model for Calculation of Normal-Tissue Complication Probability: A Systematic Literature Review. Int J Radiat Oncol Biol Phys 2022; 115:696-706.
Art
Wissenschaftlicher Artikel/Review (Englisch)
Zeitschrift
Int J Radiat Oncol Biol Phys 2022; 115
Veröffentlichungsdatum
24.08.2022
eISSN (Online)
1879-355X
Seiten
696-706
Kurzbeschreibung/Zielsetzung

The Lyman model is one of the most used radiobiological models for calculation of normal-tissue complication probability (NTCP). Since its introduction in 1985, many authors have published parameter values for the model based on clinical data of different radiotherapeutic situations. This study attempted to collect the entirety of radiobiological parameter sets published to date and provide an overview of the data basis for different variations of the model. Furthermore, it sought to compare the parameter values and calculated NTCPs for selected endpoints with sufficient data available.