Publikation
Parameters of the Lyman Model for Calculation of Normal-Tissue Complication Probability: A Systematic Literature Review.
Wissenschaftlicher Artikel/Review - 24.08.2022
Dennstädt Fabio, Medová Michaela, Putora Paul Martin, Glatzer Markus
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The Lyman model is one of the most used radiobiological models for calculation of normal-tissue complication probability (NTCP). Since its introduction in 1985, many authors have published parameter values for the model based on clinical data of different radiotherapeutic situations. This study attempted to collect the entirety of radiobiological parameter sets published to date and provide an overview of the data basis for different variations of the model. Furthermore, it sought to compare the parameter values and calculated NTCPs for selected endpoints with sufficient data available.