Art

Reichweite

Bereiche

Status

Start

Ende

Finanzierungsart

Studiendesign

Schlagwörter (Tags)

Kurzbeschreibung/Zielsetzung

Background & Aims: Controlled attenuated parameter (CAP) is a new parameter to assess steatosis of the liver, which is obtained together with elastography. Our aim was to assess the performance of CAP in an unselected population with different liver diseases.
Methods: Between March 2015 and August 2016, all patients who underwent liver biopsy for any reason were screened to meet the inclusion criteria. The CAP measurement had to be done within the same week as the biopsy and quality standards for CAP measurement
were defined. Liver biopsies were classified according to the following degrees of steatosis: S0 <5%; S1 5-33%; S2 34-66%; S3 > 66%. In addition data about fibrosis, inflammatory activity, body mass index (BMI) and liver disease were recorded.
Results: 290 patients were screened and 224 (77.2%) were included. 146 (65.2%) were male.
Conclusions: CAP shows strong association to steatosis grading. Especially the groups NAFLD/NASH vs other liver diseases.