Project
Evaluation of Controlled Attenuated Parameter (CAP) for Assessment of Liver Steatosis in an Unselected Population: a Single Center Real Life Experience
Completed · 2015 until 2017
Baumeler Stephan, Semela David, Bergamin Irina, Jochum Wolfram, Neuweiler Jörg
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Brief description/objective
Background & Aims: Controlled attenuated parameter (CAP) is a new parameter to assess steatosis of the liver, which is obtained together with elastography. Our aim was to assess the performance of CAP in an unselected population with different liver diseases.
Methods: Between March 2015 and August 2016, all patients who underwent liver biopsy for any reason were screened to meet the inclusion criteria. The CAP measurement had to be done within the same week as the biopsy and quality standards for CAP measurement
were defined. Liver biopsies were classified according to the following degrees of steatosis: S0 <5%; S1 5-33%; S2 34-66%; S3 > 66%. In addition data about fibrosis, inflammatory activity, body mass index (BMI) and liver disease were recorded.
Results: 290 patients were screened and 224 (77.2%) were included. 146 (65.2%) were male.
Conclusions: CAP shows strong association to steatosis grading. Especially the groups NAFLD/NASH vs other liver diseases.