Prof. Dr. Astrid Weyerbrock
Mesoscopic imaging of glioblastomas: Are diffusion, perfusion and spectroscopic measures influenced by the radiogenetic phenotype?
Demerath T, Weyerbrock A, Urbach H, Egger K, Kiselev V, Mast H, Staszewski O, Reinacher P, Heiland D, Lange T, Schwarzwald R, Kellner E, Simon-Gabriel C, Mader I. Mesoscopic imaging of glioblastomas: Are diffusion, perfusion and spectroscopic measures influenced by the radiogenetic phenotype?. Neuroradiol J 2016; 30:36-47.
19.11.2016Mesoscopic imaging of glioblastomas: Are diffusion, perfusion and spectroscopic measures influenced by the radiogenetic phenotype?
19.11.2016Neuroradiol J 2016; 30:36-47
Demerath Theo, Weyerbrock Astrid, Urbach Horst, Egger Karl, Kiselev Valerij G, Mast Hansjörg, Staszewski Ori, Reinacher Peter, Heiland Dieter Henrik, Lange Thomas, Schwarzwald Ralf, Kellner Elias, Simon-Gabriel Carl Philipp, Mader Irina
Amino-acid PET versus MRI guided re-irradiation in patients with recurrent glioblastoma multiforme (GLIAA) - protocol of a randomized phase II trial (NOA 10/ARO 2013-1)
Oehlke O, Weber W, Meyer P, Short S, Baumert B, Mader I, Weyerbrock A, Schneider-Fuchs S, Götz I, Nestle U, Schimek-Jasch T, Graf E, Mix M, Grosu A. Amino-acid PET versus MRI guided re-irradiation in patients with recurrent glioblastoma multiforme (GLIAA) - protocol of a randomized phase II trial (NOA 10/ARO 2013-1). BMC cancer 2016; 16:769.
05.10.2016Amino-acid PET versus MRI guided re-irradiation in patients with recurrent glioblastoma multiforme (GLIAA) - protocol of a randomized phase II trial (NOA 10/ARO 2013-1)
05.10.2016BMC cancer 2016; 16:769
Oehlke Oliver, Weber Wolfgang A, Meyer Philipp T, Short Susan C, Baumert Brigitta G, Mader Irina, Weyerbrock Astrid, Schneider-Fuchs Sabine, Götz Irina, Nestle Ursula, Schimek-Jasch Tanja, Graf Erika, Mix Michael, Grosu Anca-Ligia
Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma
Kling T, Carro M, Jörnsten R, Weyerbrock A, Vasilikos I, Dai F, Heiland D, Johansson P, Ó hAilín D, Ferrarese R, Nelander S. Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma. EBioMedicine 2016; 12:72-85.
18.09.2016Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma
18.09.2016EBioMedicine 2016; 12:72-85
Kling Teresia, Carro Maria Stella, Jörnsten Rebecka, Weyerbrock Astrid, Vasilikos Ioannis, Dai Fangping, Heiland Dieter Henrik, Johansson Patrik, Ó hAilín Darren, Ferrarese Roberto, Nelander Sven
Nitric oxide released from JS-K induces cell death by mitotic catastrophe as part of necrosis in glioblastoma multiforme
Günzle J, Osterberg N, Saavedra J, Weyerbrock A. Nitric oxide released from JS-K induces cell death by mitotic catastrophe as part of necrosis in glioblastoma multiforme. Cell Death Dis 2016; 7:e2349.
01.09.2016Nitric oxide released from JS-K induces cell death by mitotic catastrophe as part of necrosis in glioblastoma multiforme
01.09.2016Cell Death Dis 2016; 7:e2349
Günzle Jessica, Osterberg Nadja, Saavedra Joseph E, Weyerbrock Astrid
Residual Tumor Volume as Best Outcome Predictor in Low Grade Glioma - A Nine-Years Near-Randomized Survey of Surgery vs. Biopsy
Roelz R, Strohmaier D, Jabbarli R, Kraeutle R, Egger K, Coenen V, Weyerbrock A, Reinacher P. Residual Tumor Volume as Best Outcome Predictor in Low Grade Glioma - A Nine-Years Near-Randomized Survey of Surgery vs. Biopsy. Sci Rep 2016; 6:32286.
30.08.2016Residual Tumor Volume as Best Outcome Predictor in Low Grade Glioma - A Nine-Years Near-Randomized Survey of Surgery vs. Biopsy
30.08.2016Sci Rep 2016; 6:32286
Roelz Roland, Strohmaier David, Jabbarli Ramazan, Kraeutle Rainer, Egger Karl, Coenen Volker A, Weyerbrock Astrid, Reinacher Peter C
Molecular differences between cerebral blood volume and vessel size in glioblastoma multiforme
Heiland D, Weyerbrock A, Urbach H, Staszewski O, Schnell O, Pfeifer D, Kiselev V, Kellner E, Demerath T, Mader I. Molecular differences between cerebral blood volume and vessel size in glioblastoma multiforme. Oncotarget 2016
23.08.2016Molecular differences between cerebral blood volume and vessel size in glioblastoma multiforme
23.08.2016Oncotarget 2016
Heiland Dieter Henrik, Weyerbrock Astrid, Urbach Horst, Staszewski Ori, Schnell Oliver, Pfeifer Dietmar, Kiselev Valerij G, Kellner Elias, Demerath Theo, Mader Irina
Integrative Network-based Analysis of Magnetic Resonance Spectroscopy and Genome Wide Expression in Glioblastoma multiforme
Heiland D, Urbach H, Vasilikos I, Schwarzwald R, Lange T, Carro M, Pfeifer D, Schlosser P, Mader I, Weyerbrock A. Integrative Network-based Analysis of Magnetic Resonance Spectroscopy and Genome Wide Expression in Glioblastoma multiforme. Sci Rep 2016; 6:29052.
28.06.2016Integrative Network-based Analysis of Magnetic Resonance Spectroscopy and Genome Wide Expression in Glioblastoma multiforme
28.06.2016Sci Rep 2016; 6:29052
Heiland Dieter Henrik, Urbach Horst, Vasilikos Ioannis, Schwarzwald Ralf, Lange Thomas, Carro Maria Stella, Pfeifer Dietmar, Schlosser Pascal, Mader Irina, Weyerbrock Astrid
Intracerebral Hematoma Due to Aneurysm Rupture: Are There Risk Factors Beyond Aneurysm Location?
Jabbarli R, Reinhard M, Roelz R, Shah M, Niesen W, Kaier K, Taschner C, Weyerbrock A, Van Velthoven V. Intracerebral Hematoma Due to Aneurysm Rupture: Are There Risk Factors Beyond Aneurysm Location?. Neurosurgery 2016; 78:813-20.
01.06.2016Intracerebral Hematoma Due to Aneurysm Rupture: Are There Risk Factors Beyond Aneurysm Location?
01.06.2016Neurosurgery 2016; 78:813-20
Jabbarli Ramazan, Reinhard Matthias, Roelz Roland, Shah Mukesch, Niesen Wolf-Dirk, Kaier Klaus, Taschner Christian, Weyerbrock Astrid, Van Velthoven Vera
Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082)
Wick W, Golfinopoulos V, Frenel J, Campone M, Ricard D, Marosi C, Villa S, Weyerbrock A, Hopkins K, Homicsko K, Lhermitte B, Pesce G, Roth P, Stupp R, Gorlia T, Bady P, Platten M, van den Bent M, Taphoorn M, Steuve J, Brandes A, Hamou M, Wick A, Kosch M, Weller M, Hegi M. Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082). Clin Cancer Res 2016; 22:4797-4806.
03.05.2016Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082)
03.05.2016Clin Cancer Res 2016; 22:4797-4806
Wick Wolfgang, Golfinopoulos Vassilis, Frenel Jean-Sebastien, Campone Mario, Ricard Damien, Marosi Christine, Villa Salvador, Weyerbrock Astrid, Hopkins Kirsten, Homicsko Krisztian, Lhermitte Benoit, Pesce Gianfranco, Roth Patrick, Stupp Roger, Gorlia Thierry, Bady Pierre, Platten Michael, van den Bent Martin J, Taphoorn Martin J B, Steuve Jonathan, Brandes Alba A, Hamou Marie-France, Wick Antje, Kosch Markus, Weller Michael, Hegi Monika E
Glioma vessel abnormality quantification using time-of-flight MR angiography
Strumia M, Reichardt W, Staszewski O, Heiland D, Weyerbrock A, Mader I, Bock M. Glioma vessel abnormality quantification using time-of-flight MR angiography. MAGMA 2016; 29:765-75.
20.04.2016Glioma vessel abnormality quantification using time-of-flight MR angiography
20.04.2016MAGMA 2016; 29:765-75
Strumia Maddalena, Reichardt Wilfried, Staszewski Ori, Heiland Dieter Henrik, Weyerbrock Astrid, Mader Irina, Bock Michael
Bevacizumab Plus Irinotecan Versus Temozolomide in Newly Diagnosed O6-Methylguanine-DNA Methyltransferase Nonmethylated Glioblastoma: The Randomized GLARIUS Trial
Herrlinger U, Kortmann R, Mehdorn M, Tüttenberg J, Mayer-Steinacker R, Fietkau R, Brehmer S, Mack F, Stuplich M, Kebir S, Kohnen R, Dunkl E, Leutgeb B, Proescholdt M, Pietsch T, Urbach H, Belka C, Stummer W, Gerlach R, Vajkoczy P, Schäfer N, Steinbach J, Weyerbrock A, Hau P, Goldbrunner R, Friedrich F, Rohde V, Ringel F, Schlegel U, Sabel M, Ronellenfitsch M, Uhl M, Maciaczyk J, Grau S, Schnell O, Hänel M, Krex D, Glas M. Bevacizumab Plus Irinotecan Versus Temozolomide in Newly Diagnosed O6-Methylguanine-DNA Methyltransferase Nonmethylated Glioblastoma: The Randomized GLARIUS Trial. J Clin Oncol 2016; 34:1611-9.
14.03.2016Bevacizumab Plus Irinotecan Versus Temozolomide in Newly Diagnosed O6-Methylguanine-DNA Methyltransferase Nonmethylated Glioblastoma: The Randomized GLARIUS Trial
14.03.2016J Clin Oncol 2016; 34:1611-9
Herrlinger Ulrich, Kortmann Rolf-Dieter, Mehdorn Maximilian, Tüttenberg Jochen, Mayer-Steinacker Regine, Fietkau Rainer, Brehmer Stefanie, Mack Frederic, Stuplich Moritz, Kebir Sied, Kohnen Ralf, Dunkl Elmar, Leutgeb Barbara, Proescholdt Martin, Pietsch Torsten, Urbach Horst, Belka Claus, Stummer Walter, Gerlach Rüdiger, Vajkoczy Peter, Schäfer Niklas, Steinbach Joachim P, Weyerbrock Astrid, Hau Peter, Goldbrunner Roland, Friedrich Franziska, Rohde Veit, Ringel Florian, Schlegel Uwe, Sabel Michael, Ronellenfitsch Michael W, Uhl Martin, Maciaczyk Jaroslaw, Grau Stefan, Schnell Oliver, Hänel Mathias, Krex Dietmar, Glas Martin
Decrease of VEGF-A in myeloid cells attenuates glioma progression and prolongs survival in an experimental glioma model
Osterberg N, Plate K, Schaefer H, Doostkam S, Weyerbrock A, Niedermann G, Gaedicke S, Vacher J, Ferrara N, Machein M. Decrease of VEGF-A in myeloid cells attenuates glioma progression and prolongs survival in an experimental glioma model. Neuro-oncology 2016; 18:939-49.
06.03.2016Decrease of VEGF-A in myeloid cells attenuates glioma progression and prolongs survival in an experimental glioma model
06.03.2016Neuro-oncology 2016; 18:939-49
Osterberg Nadja, Plate Karl H, Schaefer Hans-Eckart, Doostkam Soroush, Weyerbrock Astrid, Niedermann Gabriele, Gaedicke Simone, Vacher Jean, Ferrara Napoleone, Machein Marcia Regina
Malignant Transformation of a Dysembryoplastic Neuroepithelial Tumor (DNET) Characterized by Genome-Wide Methylation Analysis
Heiland D, Urbach H, Schrimpf D, Capper D, Grauvogel J, Franco P, Masalha W, Hirsch M, Staszewski O, Weyerbrock A. Malignant Transformation of a Dysembryoplastic Neuroepithelial Tumor (DNET) Characterized by Genome-Wide Methylation Analysis. J Neuropathol Exp Neurol 2016; 75:358-65.
27.02.2016Malignant Transformation of a Dysembryoplastic Neuroepithelial Tumor (DNET) Characterized by Genome-Wide Methylation Analysis
27.02.2016J Neuropathol Exp Neurol 2016; 75:358-65
Heiland Dieter Henrik, Urbach Horst, Schrimpf Daniel, Capper David, Grauvogel Jürgen, Franco Pamela, Masalha Waseem, Hirsch Martin, Staszewski Ori, Weyerbrock Astrid
Early Vasospasm after Aneurysmal Subarachnoid Hemorrhage Predicts the Occurrence and Severity of Symptomatic Vasospasm and Delayed Cerebral Ischemia
Jabbarli R, Reinhard M, Shah M, Roelz R, Niesen W, Kaier K, Taschner C, Weyerbrock A, Van Velthoven V. Early Vasospasm after Aneurysmal Subarachnoid Hemorrhage Predicts the Occurrence and Severity of Symptomatic Vasospasm and Delayed Cerebral Ischemia. Cerebrovasc Dis 2016; 41:265-72.
03.02.2016Early Vasospasm after Aneurysmal Subarachnoid Hemorrhage Predicts the Occurrence and Severity of Symptomatic Vasospasm and Delayed Cerebral Ischemia
03.02.2016Cerebrovasc Dis 2016; 41:265-72
Jabbarli Ramazan, Reinhard Matthias, Shah Mukesch, Roelz Roland, Niesen Wolf-Dirk, Kaier Klaus, Taschner Christian, Weyerbrock Astrid, Van Velthoven Vera
Whole Transcriptome Screening Reveals Myelination Deficits in Dysplastic Human Temporal Neocortex
Donkels C, Zentner J, Weyerbrock A, Schulze-Bonhage A, Prinz M, Nakagawa J, Huber S, Janz P, Pfeifer D, Haas C. Whole Transcriptome Screening Reveals Myelination Deficits in Dysplastic Human Temporal Neocortex. Cereb Cortex 2016
20.01.2016Whole Transcriptome Screening Reveals Myelination Deficits in Dysplastic Human Temporal Neocortex
20.01.2016Cereb Cortex 2016
Donkels Catharina, Zentner Josef, Weyerbrock Astrid, Schulze-Bonhage Andreas, Prinz Marco, Nakagawa Julia, Huber Susanne, Janz Philipp, Pfeifer Dietmar, Haas Carola A
Stereotactic fractionated radiotherapy of the resection cavity in patients with one to three brain metastases
Bilger A, Milanovic D, Lorenz H, Oehlke O, Urbach H, Schmucker M, Weyerbrock A, Nieder C, Grosu A. Stereotactic fractionated radiotherapy of the resection cavity in patients with one to three brain metastases. Clin Neurol Neurosurg 2016; 142:81-6.
14.01.2016Stereotactic fractionated radiotherapy of the resection cavity in patients with one to three brain metastases
14.01.2016Clin Neurol Neurosurg 2016; 142:81-6
Bilger Angelika, Milanovic Dusan, Lorenz Hannah, Oehlke Oliver, Urbach Horst, Schmucker Marianne, Weyerbrock Astrid, Nieder Carsten, Grosu Anca-Ligia
The predictors and clinical impact of intraventricular hemorrhage in patients with aneurysmal subarachnoid hemorrhage
Jabbarli R, Reinhard M, Roelz R, Shah M, Niesen W, Kaier K, Taschner C, Weyerbrock A, Velthoven V. The predictors and clinical impact of intraventricular hemorrhage in patients with aneurysmal subarachnoid hemorrhage. Int J Stroke 2016; 11:68-76.
01.01.2016The predictors and clinical impact of intraventricular hemorrhage in patients with aneurysmal subarachnoid hemorrhage
01.01.2016Int J Stroke 2016; 11:68-76
Jabbarli Ramazan, Reinhard Matthias, Roelz Roland, Shah Mukesch, Niesen Wolf-Dirk, Kaier Klaus, Taschner Christian, Weyerbrock Astrid, Velthoven Vera Van
Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma
Scholz A, Meinhardt M, Weyerbrock A, Timmer M, Goldbrunner R, Deckert M, Braun C, Schittenhelm J, Frueh J, Ullrich E, Mittelbronn M, Plate K, Krex D, Herrlinger U, Glas M, Harter P, Cremer S, Yalcin B, Gurnik S, Yamaji M, Di Tacchio M, Sommer K, Baumgarten P, Bähr O, Steinbach J, Trojan J, Reiss Y. Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma. EMBO Mol Med 2015; 8:39-57.
14.12.2015Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma
14.12.2015EMBO Mol Med 2015; 8:39-57
Scholz Alexander, Meinhardt Matthias, Weyerbrock Astrid, Timmer Marco, Goldbrunner Roland, Deckert Martina, Braun Christian, Schittenhelm Jens, Frueh Jochen T, Ullrich Evelyn, Mittelbronn Michel, Plate Karl H, Krex Dietmar, Herrlinger Ulrich, Glas Martin, Harter Patrick N, Cremer Sebastian, Yalcin Burak H, Gurnik Stefanie, Yamaji Maiko, Di Tacchio Mariangela, Sommer Kathleen, Baumgarten Peter, Bähr Oliver, Steinbach Joachim P, Trojan Jörg, Reiss Yvonne
Clinical benefit from resection of recurrent glioblastomas: results of a multicenter study including 503 patients with recurrent glioblastomas undergoing surgical resection
Ringel F, Simon M, Meyer B, Schucht P, Senft C, Westermaier T, Weyerbrock A, Misch M, Bock H, Krex D, Sabel M, Pape H. Clinical benefit from resection of recurrent glioblastomas: results of a multicenter study including 503 patients with recurrent glioblastomas undergoing surgical resection. Neuro-oncology 2015; 18:96-104.
04.08.2015Clinical benefit from resection of recurrent glioblastomas: results of a multicenter study including 503 patients with recurrent glioblastomas undergoing surgical resection
04.08.2015Neuro-oncology 2015; 18:96-104
Ringel Florian, Simon Matthias, Meyer Bernhard, Schucht Philippe, Senft Christian, Westermaier Thomas, Weyerbrock Astrid, Misch Martin, Bock Hans Christoph, Krex Dietmar, Sabel Michael, Pape Haiko
JS-K, a glutathione S-transferase-activated nitric oxide donor with antineoplastic activity in malignant gliomas
Weyerbrock A, Keefer L, Saavedra J, Bette S, Werres A, Kogias E, Baumer B, Psarras N, Osterberg N, Papazoglou A. JS-K, a glutathione S-transferase-activated nitric oxide donor with antineoplastic activity in malignant gliomas. Neurosurgery 2012; 70:497-510; discussion 510.
01.02.2012JS-K, a glutathione S-transferase-activated nitric oxide donor with antineoplastic activity in malignant gliomas
01.02.2012Neurosurgery 2012; 70:497-510; discussion 510
Weyerbrock Astrid, Keefer Larry K, Saavedra Joseph E, Bette Stefanie, Werres Anna, Kogias Evangelos, Baumer Brunhilde, Psarras Nikolaos, Osterberg Nadja, Papazoglou Anna